Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs.
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Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's diseaseInside out: the role of nucleocytoplasmic transport in ALS and FTLDMechanisms of FUS mutations in familial amyotrophic lateral sclerosisImmunoprecipitation and mass spectrometry defines an extensive RBM45 protein-protein interaction networkThe Use of Stem Cells to Model Amyotrophic Lateral Sclerosis and Frontotemporal Dementia: From Basic Research to Regenerative MedicineParkin Regulation and Neurodegenerative DisordersFUS-mediated regulation of alternative RNA processing in neurons: insights from global transcriptome analysisGolgi Fragmentation in ALS Motor Neurons. New Mechanisms Targeting Microtubules, Tethers, and Transport VesiclesAlterations in stress granule dynamics driven by TDP-43 and FUS: a link to pathological inclusions in ALS?Unveiling the hidden function of long non-coding RNA by identifying its major partner-proteinConverging mechanisms in ALS and FTD: disrupted RNA and protein homeostasisState of play in amyotrophic lateral sclerosis geneticsNeuronal RNA-binding proteins in health and diseaseThe function of RNA-binding proteins at the synapse: implications for neurodegenerationRNA-binding proteins in neurodegeneration: Seq and you shall receiveNxf1 natural variant E610G is a semi-dominant suppressor of IAP-induced RNA processing defectsRNA-processing protein TDP-43 regulates FOXO-dependent protein quality control in stress responseRecursive splicing in long vertebrate genes.A loss of FUS/TLS function leads to impaired cellular proliferationEarly lethality and neuronal proteinopathy in mice expressing cytoplasm-targeted FUS that lacks the RNA recognition motif.Pathogenesis of FUS-associated ALS and FTD: insights from rodent modelsDefective control of pre-messenger RNA splicing in human diseaseA Case for Microtubule Vulnerability in Amyotrophic Lateral Sclerosis: Altered Dynamics During DiseaseTDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets.Autophagosome dynamics in neurodegeneration at a glanceSMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control terminationContext-dependent control of alternative splicing by RNA-binding proteinsA majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulationOxr1 improves pathogenic cellular features of ALS-associated FUS and TDP-43 mutationsExploring new pathways of neurodegeneration in ALS: the role of mitochondria quality controlALS as a distal axonopathy: molecular mechanisms affecting neuromuscular junction stability in the presymptomatic stages of the diseaseMisregulation of Alternative Splicing in a Mouse Model of Rett SyndromeEWS and FUS bind a subset of transcribed genes encoding proteins enriched in RNA regulatory functionsWhat causes amyotrophic lateral sclerosis?FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2.RNA seeds higher-order assembly of FUS protein.FUS is sequestered in nuclear aggregates in ALS patient fibroblasts.Nucleic acid-binding specificity of human FUS protein.Drosophila TDP-43 dysfunction in glia and muscle cells cause cytological and behavioural phenotypes that characterize ALS and FTLDAxonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations.
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Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Divergent roles of ALS-linked ...... in processing long pre-mRNAs.
@ast
Divergent roles of ALS-linked ...... in processing long pre-mRNAs.
@en
type
label
Divergent roles of ALS-linked ...... in processing long pre-mRNAs.
@ast
Divergent roles of ALS-linked ...... in processing long pre-mRNAs.
@en
prefLabel
Divergent roles of ALS-linked ...... in processing long pre-mRNAs.
@ast
Divergent roles of ALS-linked ...... in processing long pre-mRNAs.
@en
P2093
P2860
P356
P1433
P1476
Divergent roles of ALS-linked ...... in processing long pre-mRNAs.
@en
P2093
Aneeza S Kim
Anthony Q Vu
C Frank Bennett
Curt Mazur
Don W Cleveland
Edward Wancewicz
Gene W Yeo
Geoffrey G Hicks
John Paul Donohue
P2860
P2888
P304
P356
10.1038/NN.3230
P407
P577
2012-09-30T00:00:00Z
P5875
P6179
1033473336