DNA-binding-defective mutants of the Epstein-Barr virus lytic switch activator Zta transactivate with altered specificities
about
Methylation-dependent binding of the epstein-barr virus BZLF1 protein to viral promotersEpstein-Barr virus immediate-early proteins BZLF1 and BRLF1 activate the ATF2 transcription factor by increasing the levels of phosphorylated p38 and c-Jun N-terminal kinasesThe Epstein-Barr virus protein BRLF1 activates S phase entry through E2F1 induction.The Epstein-Barr virus BZLF1 protein interacts physically and functionally with the histone acetylase CREB-binding protein.Arsenic trioxide inhibits EBV reactivation and promotes cell death in EBV-positive lymphoma cells.Epstein-Barr virus immediate-early protein BRLF1 interacts with CBP, promoting enhanced BRLF1 transactivation.BZLF1 activation of the methylated form of the BRLF1 immediate-early promoter is regulated by BZLF1 residue 186.CCAAT/enhancer binding protein alpha interacts with ZTA and mediates ZTA-induced p21(CIP-1) accumulation and G(1) cell cycle arrest during the Epstein-Barr virus lytic cycle.Epstein-Barr virus Zta upregulates matrix metalloproteinases 3 and 9 that synergistically promote cell invasion in vitro.Physical and functional interaction of the Epstein-Barr virus BZLF1 transactivator with the retinoic acid receptors RAR alpha and RXR alpha.Amino acids in the basic domain of Epstein-Barr virus ZEBRA protein play distinct roles in DNA binding, activation of early lytic gene expression, and promotion of viral DNA replication.Epstein-Barr virus Zta-induced immunomodulators from nasopharyngeal carcinoma cells upregulate interleukin-10 production from monocytesThe Epstein-Barr virus latency BamHI-Q promoter is positively regulated by STATs and Zta interference with JAK/STAT activation leads to loss of BamHI-Q promoter activityIdentification of cellular target genes of the Epstein-Barr virus transactivator Zta: activation of transforming growth factor beta igh3 (TGF-beta igh3) and TGF-beta 1The Epstein-Barr virus bZIP transcription factor Zta causes G0/G1 cell cycle arrest through induction of cyclin-dependent kinase inhibitorsCharacterization of the ZI domains in the Epstein-Barr virus BZLF1 gene promoter: role in phorbol ester induction.Functional and physical interactions between the Epstein-Barr virus (EBV) proteins BZLF1 and BMRF1: Effects on EBV transcription and lytic replicationEpstein-Barr virus lytic transactivator Zta enhances chemotactic activity through induction of interleukin-8 in nasopharyngeal carcinoma cells.Host-cell-determined methylation of specific Epstein-Barr virus promoters regulates the choice between distinct viral latency programsCCAAT/enhancer binding protein alpha binds to the Epstein-Barr virus (EBV) ZTA protein through oligomeric interactions and contributes to cooperative transcriptional activation of the ZTA promoter through direct binding to the ZII and ZIIIB motifs dThe Epstein-Barr virus BamHI F promoter is an early lytic promoter: lack of correlation with EBNA 1 gene transcription in group 1 Burkitt's lymphoma cell linesReplication of Epstein-Barr virus oriLyt: lack of a dedicated virally encoded origin-binding protein and dependence on Zta in cotransfection assays.Stimulation of CREB binding protein nucleosomal histone acetyltransferase activity by a class of transcriptional activators.Biophysical analysis of natural variants of the multimerization region of Epstein-Barr virus lytic-switch protein BZLF1.Construction and expression of a spliced variant of Epstein-Barr virus bzlf1 and preparation of its polyclonal antibody.Comparing transcriptional activation and autostimulation by ZEBRA and ZEBRA/c-Fos chimeras.Constitutive activation of Epstein-Barr virus (EBV) nuclear antigen 1 gene transcription by IRF1 and IRF2 during restricted EBV latency.Repression of CIITA by the Epstein-Barr virus transcription factor Zta is independent of its dimerization and DNA binding.G0/G1 growth arrest mediated by a region encompassing the basic leucine zipper (bZIP) domain of the Epstein-Barr virus transactivator Zta.
P2860
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P2860
DNA-binding-defective mutants of the Epstein-Barr virus lytic switch activator Zta transactivate with altered specificities
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
DNA-binding-defective mutants ...... ate with altered specificities
@ast
DNA-binding-defective mutants ...... ate with altered specificities
@en
type
label
DNA-binding-defective mutants ...... ate with altered specificities
@ast
DNA-binding-defective mutants ...... ate with altered specificities
@en
prefLabel
DNA-binding-defective mutants ...... ate with altered specificities
@ast
DNA-binding-defective mutants ...... ate with altered specificities
@en
P2093
P2860
P356
P1476
DNA-binding-defective mutants ...... ate with altered specificities
@en
P2093
A M Borras
E K Flemington
P2860
P304
P356
10.1128/MCB.14.5.3041
P407
P577
1994-05-01T00:00:00Z