Dynamic modelling and analysis of biochemical networks: mechanism-based models and model-based experiments.
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The (Mathematical) Modeling Process in BiosciencesSobol Sensitivity Analysis: A Tool to Guide the Development and Evaluation of Systems Pharmacology ModelsNew types of experimental data shape the use of enzyme kinetics for dynamic network modelingComputational approaches for understanding energy metabolismComputationally Modeling Lipid Metabolism and Aging: A Mini-reviewBoolean network model predicts cell cycle sequence of fission yeastStimulus design for model selection and validation in cell signalingExtended kalman filter for estimation of parameters in nonlinear state-space models of biochemical networksMathematical modelling of polyamine metabolism in bloodstream-form Trypanosoma brucei: an application to drug target identificationParameter trajectory analysis to identify treatment effects of pharmacological interventionsk-OptForce: integrating kinetics with flux balance analysis for strain designDynamic analysis of integrated signaling, metabolic, and regulatory networks.Robust and efficient parameter estimation in dynamic models of biological systemsA dynamic analysis of IRS-PKR signaling in liver cells: a discrete modeling approach.Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic dataA systems biology framework for modeling metabolic enzyme inhibition of Mycobacterium tuberculosis.Cell cycle-related cyclin b1 quantificationDeveloping optimal input design strategies in cancer systems biology with applications to microfluidic device engineering.An iterative identification procedure for dynamic modeling of biochemical networksConstruction of a large scale integrated map of macrophage pathogen recognition and effector systems.Fathead minnow steroidogenesis: in silico analyses reveals tradeoffs between nominal target efficacy and robustness to cross-talk.A systems immunology approach to plasmacytoid dendritic cell function in cytopathic virus infections.Thermodynamic modeling of transcription: sensitivity analysis differentiates biological mechanism from mathematical model-induced effectsComputational modeling of mitochondrial energy transduction.A computational and experimental study of the regulatory mechanisms of the complement systemTime-resolved in silico modeling of fine-tuned cAMP signaling in platelets: feedback loops, titrated phosphorylations and pharmacological modulation.The impact of CDK inhibition in human malignancies associated with pronounced defects in apoptosis: advantages of multi-targeting small molecules.Inferring robust gene networks from expression data by a sensitivity-based incremental evolution method.A cooperative strategy for parameter estimation in large scale systems biology models.Nonparametric simulation of signal transduction networks with semi-synchronized updateKinetic and dynamic computational model-based characterization of new proteins in mice: application to interferon alpha linked to apolipoprotein A-I.Random parameter sampling of a generic three-tier MAPK cascade model reveals major factors affecting its versatile dynamics.Optimization and model reduction in the high dimensional parameter space of a budding yeast cell cycle model.Simultaneous model discrimination and parameter estimation in dynamic models of cellular systemsReverse-engineering post-transcriptional regulation of gap genes in Drosophila melanogasterNetwork topology and parameter estimation: from experimental design methods to gene regulatory network kinetics using a community based approachBioPreDyn-bench: a suite of benchmark problems for dynamic modelling in systems biology.Global sensitivity analysis of a dynamic model for gene expression in Drosophila embryos.Mathematical modeling of biomolecular network dynamicsComplementing ODE-Based System Analysis Using Boolean Networks Derived from an Euler-Like Transformation.
P2860
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P2860
Dynamic modelling and analysis of biochemical networks: mechanism-based models and model-based experiments.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Dynamic modelling and analysis ...... s and model-based experiments.
@ast
Dynamic modelling and analysis ...... s and model-based experiments.
@en
type
label
Dynamic modelling and analysis ...... s and model-based experiments.
@ast
Dynamic modelling and analysis ...... s and model-based experiments.
@en
prefLabel
Dynamic modelling and analysis ...... s and model-based experiments.
@ast
Dynamic modelling and analysis ...... s and model-based experiments.
@en
P356
P1476
Dynamic modelling and analysis ...... ls and model-based experiments
@en
P2093
Natal A W van Riel
P304
P356
10.1093/BIB/BBL040
P577
2006-11-14T00:00:00Z