Triptolide induces cell death in pancreatic cancer cells by apoptotic and autophagic pathways.
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Minnelide: a novel therapeutic that promotes apoptosis in non-small cell lung carcinoma in vivoMinnelide, a novel drug for pancreatic and liver cancerTriptolide induces growth inhibition and apoptosis of human laryngocarcinoma cells by enhancing p53 activities and suppressing E6-mediated p53 degradationMinnelide/Triptolide Impairs Mitochondrial Function by Regulating SIRT3 in P53-Dependent Manner in Non-Small Cell Lung CancerROS-mediated autophagy induced by dysregulation of lipid metabolism plays a protective role in colorectal cancer cells treated with gambogic acid.Triptolide sensitizes pancreatic cancer cells to TRAIL-induced activation of the death receptor pathwayTriptolide activates unfolded protein response leading to chronic ER stress in pancreatic cancer cells.Monascuspiloin enhances the radiation sensitivity of human prostate cancer cells by stimulating endoplasmic reticulum stress and inducing autophagy.Autophagy in pancreatic cancer: an emerging mechanism of cell death.The Role of Nutraceuticals in Pancreatic Cancer Prevention and Therapy: Targeting Cellular Signaling, MicroRNAs, and Epigenome.Chloroquine enhances gefitinib cytotoxicity in gefitinib-resistant nonsmall cell lung cancer cells.Primary and liver metastasis-derived cell lines from KrasG12D; Trp53R172H; Pdx-1 Cre animals undergo apoptosis in response to triptolide.Suppression of the migration and invasion is mediated by triptolide in B16F10 mouse melanoma cells through the NF-kappaB-dependent pathway.Inhibition of tumor cellular proteasome activity by triptolide extracted from the Chinese medicinal plant 'thunder god vine'.Triptolide increases transcript and protein levels of survival motor neurons in human SMA fibroblasts and improves survival in SMA-like miceMinnelide Overcomes Oxaliplatin Resistance by Downregulating the DNA Repair Pathway in Pancreatic Cancer.Triptolide enhances the tumoricidal activity of TRAIL against renal cell carcinomaTriptolide inhibits MDM2 and induces apoptosis in acute lymphoblastic leukemia cells through a p53-independent pathway.Triptolide induces protective autophagy through activation of the CaMKKβ-AMPK signaling pathway in prostate cancer cellsTriptolide induces the expression of miR-142-3p: a negative regulator of heat shock protein 70 and pancreatic cancer cell proliferationTriptolide abrogates growth of colon cancer and induces cell cycle arrest by inhibiting transcriptional activation of E2F.Triptolide-induced cell death in pancreatic cancer is mediated by O-GlcNAc modification of transcription factor Sp1.Methamphetamine induces autophagy as a pro-survival response against apoptotic endothelial cell death through the Kappa opioid receptor.Triptolide: structural modifications, structure-activity relationships, bioactivities, clinical development and mechanisms.Triptolide with potential medicinal value for diseases of the central nervous system.Possible role of autophagy in the treatment of pancreatic cancer with histone deacetylase inhibitors.Role of autophagy and its significance in cellular homeostasis.Control of Apoptosis in Treatment and Biology of Pancreatic Cancer.Cell death mechanisms of plant-derived anticancer drugs: beyond apoptosis.Inhibiting heat shock protein 90 and the ubiquitin-proteasome pathway impairs metabolic homeostasis and leads to cell death in human pancreatic cancer cells.Autophagy in 5-Fluorouracil Therapy in Gastrointestinal Cancer: Trends and Challenges.Arsenic trioxide and triptolide synergistically induce apoptosis in the SKM‑1 human myelodysplastic syndrome cell line.Targeting Hsp70: A possible therapy for cancer.LB-1 Exerts Antitumor Activity in Pancreatic Cancer by Inhibiting HIF-1α and Stat3 Signaling.Role of autophagy in apoptotic regulation by Akt in pancreatic cancermiR-204 mediated loss of Myeloid cell leukemia-1 results in pancreatic cancer cell death.Natural Compounds As Modulators of Non-apoptotic Cell Death in Cancer Cells.Triptolide triggers the apoptosis of pancreatic cancer cells via the downregulation of Decoy receptor 3 expression.Antitumor effects of cytoplasmic delivery of an innate adjuvant receptor ligand, poly(I:C), on human breast cancer.Tripchlorolide induces cell death in lung cancer cells by autophagy.
P2860
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P2860
Triptolide induces cell death in pancreatic cancer cells by apoptotic and autophagic pathways.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Triptolide induces cell death ...... totic and autophagic pathways.
@ast
Triptolide induces cell death ...... totic and autophagic pathways.
@en
type
label
Triptolide induces cell death ...... totic and autophagic pathways.
@ast
Triptolide induces cell death ...... totic and autophagic pathways.
@en
prefLabel
Triptolide induces cell death ...... totic and autophagic pathways.
@ast
Triptolide induces cell death ...... totic and autophagic pathways.
@en
P2093
P2860
P1433
P1476
Triptolide induces cell death ...... totic and autophagic pathways.
@en
P2093
Ashok K Saluja
Daniel Borja-Cacho
Mara B Antonoff
Nameeta Mujumdar
Rajinder Dawra
Rohit Chugh
Selwyn M Vickers
Tiffany N Mackenzie
Veena Sangwan
Vikas Dudeja
P2860
P304
P356
10.1053/J.GASTRO.2010.04.046
P407
P577
2010-04-29T00:00:00Z