Molecular determinants of macrophage tropism and viral persistence: importance of single amino acid changes in the polymerase and glycoprotein of lymphocytic choriomeningitis virus
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Viral quasispecies evolutionLymphocytic choriomeningitis virus infection in FVB mouse produces hemorrhagic diseaseInterleukin-10 plays an early role in generating virus-specific T cell anergy.Platelets support a protective immune response to LCMV by preventing splenic necrosis.A role for perforin in downregulating T-cell responses during chronic viral infection.Retroviral vectors pseudotyped with lymphocytic choriomeningitis virus.Differences in affinity of binding of lymphocytic choriomeningitis virus strains to the cellular receptor alpha-dystroglycan correlate with viral tropism and disease kinetics.Molecular determinants of infectious pancreatic necrosis virus virulence and cell culture adaptation.The pulmonary localization of virus-specific T lymphocytes is governed by the tissue tropism of infection.Molecular indetermination in the transition to error catastrophe: systematic elimination of lymphocytic choriomeningitis virus through mutagenesis does not correlate linearly with large increases in mutant spectrum complexity.Loss of anti-viral immunity by infection with a virus encoding a cross-reactive pathogenic epitope.Effects of promyelocytic leukemia protein on virus-host balance.Recombinant Listeria monocytogenes as a live vaccine vehicle for the induction of protective anti-viral cell-mediated immunityViral replicative capacity is the primary determinant of lymphocytic choriomeningitis virus persistence and immunosuppression.OX40 facilitates control of a persistent virus infection.Rescue from cloned cDNAs and in vivo characterization of recombinant pathogenic Romero and live-attenuated Candid #1 strains of Junin virus, the causative agent of Argentine hemorrhagic fever disease.Cell-intrinsic transforming growth factor-beta signaling mediates virus-specific CD8+ T cell deletion and viral persistence in vivoPoint mutation in the glycoprotein of lymphocytic choriomeningitis virus is necessary for receptor binding, dendritic cell infection, and long-term persistence.The role of dendritic cells in viral persistenceArenavirus variations due to host-specific adaptation.Hypomorphic mutation in the site-1 protease Mbtps1 endows resistance to persistent viral infection in a cell-specific manner.Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment.Early virus-host interactions dictate the course of a persistent infectionLymphocytic choriomeningitis virus persistence promotes effector-like memory differentiation and enhances mucosal T cell distributionTargeted deletion of FGL2 leads to increased early viral replication and enhanced adaptive immunity in a murine model of acute viral hepatitis caused by LCMV WEAntibody effector functions mediated by Fcγ-receptors are compromised during persistent viral infection.Infection of dendritic cells by lymphocytic choriomeningitis virus.Impaired responsiveness to gamma interferon of macrophages infected with lymphocytic choriomeningitis virus clone 13: susceptibility to histoplasmosis.Inflammatory monocytes recruited to the liver within 24 hours after virus-induced inflammation resemble Kupffer cells but are functionally distinct.Memory T cells from minor histocompatibility antigen-vaccinated and virus-immune donors improve GVL and immune reconstitution.Polymicrobial Sepsis Increases Susceptibility to Chronic Viral Infection and Exacerbates CD8+ T Cell Exhaustion.Specific history of heterologous virus infections determines anti-viral immunity and immunopathology in the lung.Virus-induced immunosuppression: immune system-mediated destruction of virus-infected dendritic cells results in generalized immune suppression.DNA vaccination against persistent viral infection.Ectromelia virus RING finger protein is localized in virus factories and is required for virus replication in macrophagesEmergence of virus escape mutants after immunization with epitope vaccine.Clearance of an immunosuppressive virus from the CNS coincides with immune reanimation and diversification.Competitive selection in vivo by a cell for one variant over another: implications for RNA virus quasispecies in vivo.Antibody prevents the establishment of persistent arenavirus infection in synergy with endogenous T cells.Immune function in mice lacking the perforin gene
P2860
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P2860
Molecular determinants of macrophage tropism and viral persistence: importance of single amino acid changes in the polymerase and glycoprotein of lymphocytic choriomeningitis virus
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Molecular determinants of macr ...... hocytic choriomeningitis virus
@ast
Molecular determinants of macr ...... hocytic choriomeningitis virus
@en
type
label
Molecular determinants of macr ...... hocytic choriomeningitis virus
@ast
Molecular determinants of macr ...... hocytic choriomeningitis virus
@en
prefLabel
Molecular determinants of macr ...... hocytic choriomeningitis virus
@ast
Molecular determinants of macr ...... hocytic choriomeningitis virus
@en
P2093
P2860
P921
P1433
P1476
Molecular determinants of macr ...... hocytic choriomeningitis virus
@en
P2093
M Matloubian
S R Kolhekar
T Somasundaram
P2860
P304
P407
P577
1993-12-01T00:00:00Z