FOXO3 signalling links ATM to the p53 apoptotic pathway following DNA damage.
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Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexesAuranofin displays anticancer activity against ovarian cancer cells through FOXO3 activation independent of p53Mitochondria and FOXO3: breath or diePhase I/Ib study of olaparib and carboplatin in BRCA1 or BRCA2 mutation-associated breast or ovarian cancer with biomarker analyses.A novel synthetic compound 3-amino-3-(4-fluoro-phenyl)-1H-quinoline-2,4-dione (KR22332) exerts a radioprotective effect via the inhibition of mitochondrial dysfunction and generation of reactive oxygen species.Reprogramming ovarian and breast cancer cells into non-cancerous cells by low-dose metformin or SN-38 through FOXO3 activationDoxorubicin and 5-fluorouracil induced accumulation and transcriptional activity of p53 are independent of the phosphorylation at serine 15 in MCF-7 breast cancer cellsThe Novel Ribonucleotide Reductase Inhibitor COH29 Inhibits DNA Repair In VitroCell proliferation is a key determinant of the outcome of FOXO3a activation.miR-93 promotes cell proliferation in gliomas through activation of PI3K/Akt signaling pathway.Pretreatment with Lycopene Attenuates Oxidative Stress-Induced Apoptosis in Human Mesenchymal Stem Cells.BMCC1, which is an interacting partner of BCL2, attenuates AKT activity, accompanied by apoptosis.Effects of Low-Dose Bisphenol A on DNA Damage and Proliferation of Breast Cells: The Role of c-MycFunctional DNA demethylation is accompanied by chromatin accessibility.Increased sensitivity of BRCA defective triple negative breast tumors to plumbagin through induction of DNA Double Strand Breaks (DSB).Rationale-based therapeutic combinations with PI3K inhibitors in cancer treatmentNOTCH1 Inhibits Activation of ATM by Impairing the Formation of an ATM-FOXO3a-KAT5/Tip60 Complex.Antioxidant effects of Cirsium setidens extract on oxidative stress in human mesenchymal stem cells.Pharmacological activation of FOXO3 suppresses triple-negative breast cancer in vitro and in vivoOrganelle-specific initiation of cell death.The effect of Bacopa monnieri on gene expression levels in SH-SY5Y human neuroblastoma cells.The herbal compound geniposide rescues formaldehyde-induced apoptosis in N2a neuroblastoma cells.Histone H2AX Is Involved in FoxO3a-Mediated Transcriptional Responses to Ionizing Radiation to Maintain Genome Stability.Loss of foxo rescues stem cell aging in Drosophila germ line.Decreased FOXO3 within advanced human colon cancer: implications of tumour suppressor function.Ataxia telangiectasia syndrome: moonlighting ATM.FoxO transcription factors in cancer metabolism.
P2860
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P2860
FOXO3 signalling links ATM to the p53 apoptotic pathway following DNA damage.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
FOXO3 signalling links ATM to the p53 apoptotic pathway following DNA damage.
@ast
FOXO3 signalling links ATM to the p53 apoptotic pathway following DNA damage.
@en
type
label
FOXO3 signalling links ATM to the p53 apoptotic pathway following DNA damage.
@ast
FOXO3 signalling links ATM to the p53 apoptotic pathway following DNA damage.
@en
prefLabel
FOXO3 signalling links ATM to the p53 apoptotic pathway following DNA damage.
@ast
FOXO3 signalling links ATM to the p53 apoptotic pathway following DNA damage.
@en
P2093
P2860
P356
P1476
FOXO3 signalling links ATM to the p53 apoptotic pathway following DNA damage.
@en
P2093
David J Chen
Jonathan S Berek
Masa-Aki Ikeda
Mickey C-T Hu
See-Hyoung Park
Shih-Ya Wang
Wen-Bin Tsai
Young Min Chung
P2860
P2888
P356
10.1038/NCOMMS2008
P407
P577
2012-01-01T00:00:00Z