about
Functional significance of the interaction with Ku in DNA double-strand break recognition of XLFHuman RECQL5 participates in the removal of endogenous DNA damageAPLF promotes the assembly and activity of non-homologous end joining protein complexesATM-mediated phosphorylation of polynucleotide kinase/phosphatase is required for effective DNA double-strand break repairInteractome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathwayATM damage response and XLF repair factor are functionally redundant in joining DNA breaksThe dynamics of Ku70/80 and DNA-PKcs at DSBs induced by ionizing radiation is dependent on the complexity of damageDynamics of DNA damage response proteins at DNA breaks: a focus on protein modificationsFunctional redundancy between the XLF and DNA-PKcs DNA repair factors in V(D)J recombination and nonhomologous DNA end joiningA human XRCC4-XLF complex bridges DNAXRCC4's interaction with XLF is required for coding (but not signal) end joiningXLF-Cernunnos promotes DNA ligase IV-XRCC4 re-adenylation following ligationStructural and functional interaction between the human DNA repair proteins DNA ligase IV and XRCC4The role of RecQ helicases in non-homologous end-joiningDNA-PK: a dynamic enzyme in a versatile DSB repair pathwayGenotypic characteristics of resistant tumors to pre-operative ionizing radiation in rectal cancerXRCC4 Protein Interactions with XRCC4-like Factor (XLF) Create an Extended Grooved Scaffold for DNA Ligation and Double Strand Break RepairStructural Insights into the Role of Domain Flexibility in Human DNA Ligase IVYeast Nej1 is a key participant in the initial end binding and final ligation steps of nonhomologous end joining.Xbp1-mediated histone H4 deacetylation contributes to DNA double-strand break repair in yeast.Ubiquitylation, neddylation and the DNA damage responseTRF2 interaction with Ku heterotetramerization interface gives insight into c-NHEJ prevention at human telomeresRole of non-homologous end joining in V(D)J recombinationRegulation of pairing between broken DNA-containing chromatin regions by Ku80, DNA-PKcs, ATM, and 53BP1The involvement of human RECQL4 in DNA double-strand break repair.Ku and DNA-dependent protein kinase dynamic conformations and assembly regulate DNA binding and the initial non-homologous end joining complex.Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites.Dynamics of the PI3K-like protein kinase members ATM and DNA-PKcs at DNA double strand breaks.Werner syndrome protein positively regulates XRCC4-like factor transcriptionNon-homologous end joining: emerging themes and unanswered questions.Taking a Bad Turn: Compromised DNA Damage Response in LeukemiaRegulation of the DNA Damage Response to DSBs by Post-Translational Modifications.Structural insights into NHEJ: building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a timeRole of SUMO:SIM-mediated protein-protein interaction in non-homologous end joining.In vitro non-homologous DNA end joining assays--the 20th anniversary.MU2 and HP1a regulate the recognition of double strand breaks in Drosophila melanogaster.Delineation of the Xrcc4-interacting region in the globular head domain of cernunnos/XLF.Persistently bound Ku at DNA ends attenuates DNA end resection and homologous recombinationCernunnos influences human immunoglobulin class switch recombination and may be associated with B cell lymphomagenesisCharacterization of DDRI-18 (3,3'-(1H,3'H-5,5'-bibenzo[d]imidazole-2,2'-diyl)dianiline), a novel small molecule inhibitor modulating the DNA damage response.
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Ku recruits XLF to DNA double-strand breaks
@ast
Ku recruits XLF to DNA double-strand breaks
@en
Ku recruits XLF to DNA double-strand breaks
@en-gb
Ku recruits XLF to DNA double-strand breaks
@nl
type
label
Ku recruits XLF to DNA double-strand breaks
@ast
Ku recruits XLF to DNA double-strand breaks
@en
Ku recruits XLF to DNA double-strand breaks
@en-gb
Ku recruits XLF to DNA double-strand breaks
@nl
prefLabel
Ku recruits XLF to DNA double-strand breaks
@ast
Ku recruits XLF to DNA double-strand breaks
@en
Ku recruits XLF to DNA double-strand breaks
@en-gb
Ku recruits XLF to DNA double-strand breaks
@nl
P2093
P2860
P3181
P356
P1433
P1476
Ku recruits XLF to DNA double-strand breaks
@en
P2093
Aroumougame Asaithamby
David J Chen
Eric Weterings
Keiko Morotomi-Yano
Ken-ichi Yano
Kyung-Jong Lee
Naoya Uematsu
Shih-Ya Wang
P2860
P3181
P356
10.1038/SJ.EMBOR.7401137
P407
P577
2008-01-01T00:00:00Z