about
Interactions of metals and Apolipoprotein E in Alzheimer's diseaseTowards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesThe role of iron-induced fibrin in the pathogenesis of Alzheimer's disease and the protective role of magnesiumMetal ionophore treatment restores dendritic spine density and synaptic protein levels in a mouse model of Alzheimer's diseaseIn vitro Pb exposure disturbs the balance between Aβ production and elimination: the role of AβPP and neprilysinIron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseasesThioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signalingBlood cadmium levels and Alzheimer's disease mortality risk in older US adultsA Bacterial Component to Alzheimer’s-Type Dementia Seen via a Systems Biology Approach that Links Iron Dysregulation and Inflammagen Shedding to DiseaseAutoimmune manifestations in the 3xTg-AD model of Alzheimer's disease.Copper promotes the trafficking of the amyloid precursor proteinMapping the interactome of overexpressed RAF kinase inhibitor protein in a gastric cancer cell lineAmyloid beta-protein assembly as a therapeutic target of Alzheimer's disease.Positron emission tomography for measurement of copper fluxes in live organisms.The native copper- and zinc-binding protein metallothionein blocks copper-mediated Abeta aggregation and toxicity in rat cortical neurons.Role of metal ions in the cognitive decline of Down syndrome.A prochelator activated by beta-secretase inhibits Abeta aggregation and suppresses copper-induced reactive oxygen species formation.Value in development of a TAPIR-like mouse monoclonal antibody to Abeta.Effects of dietary supplementation of carnosine on mitochondrial dysfunction, amyloid pathology, and cognitive deficits in 3xTg-AD mice.Evolutionary implications of metal binding features in different species' prion protein: an inorganic point of view.Metal imaging in neurodegenerative diseases.The amyloid-beta peptide of Alzheimer's disease binds Cu(I) in a linear bis-his coordination environment: insight into a possible neuroprotective mechanism for the amyloid-beta peptideRatiometric and intensity-based zinc sensors built on rhodol and rhodamine platforms.Metal chaperones: a holistic approach to the treatment of Alzheimer's diseaseIn vivo detection of amyloid-β deposits using heavy chain antibody fragments in a transgenic mouse model for Alzheimer's diseaseCurrent and future treatments for Alzheimer's diseaseDisease-modifying treatments for Alzheimer's disease.Different 8-hydroxyquinolines protect models of TDP-43 protein, α-synuclein, and polyglutamine proteotoxicity through distinct mechanisms.Change in the characteristics of ferritin induces iron imbalance in prion disease affected brains.Ocular manifestations of Alzheimer's disease in animal models.Serum trace element differences between Schizophrenia patients and controls in the Han Chinese population.Autonomous requirements of the Menkes disease protein in the nervous system.Alzheimer's disease-associated neurotoxic peptide amyloid-β impairs base excision repair in human neuroblastoma cellsIdentification of novel genes that modify phenotypes induced by Alzheimer's beta-amyloid overexpression in DrosophilaComparison of Metal Levels between Postmortem Brain and Ventricular Fluid in Alzheimer's Disease and Nondemented Elderly Controls.Copper ligation to soluble oligomers of the English mutant of the amyloid-β peptide yields a linear Cu(I) site that is resistant to O2 oxidation.Inhibition of human high-affinity copper importer Ctr1 orthologous in the nervous system of Drosophila ameliorates Aβ42-induced Alzheimer's disease-like symptomsNeuronal protein trafficking associated with Alzheimer disease: from APP and BACE1 to glutamate receptorsTherapeutics for Alzheimer's disease based on the metal hypothesisNeuroinflammation in Alzheimer's disease: mechanisms, pathologic consequences, and potential for therapeutic manipulation
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Metals and Alzheimer's disease.
@ast
Metals and Alzheimer's disease.
@en
type
label
Metals and Alzheimer's disease.
@ast
Metals and Alzheimer's disease.
@en
prefLabel
Metals and Alzheimer's disease.
@ast
Metals and Alzheimer's disease.
@en
P1476
Metals and Alzheimer's disease.
@en
P2093
Ashley I Bush
Paul A Adlard
P304
P577
2006-11-01T00:00:00Z