Tissue-specific regulation of mouse hepatocyte nuclear factor 4 expression
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Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genesHNF1beta/TCF2 mutations impair transactivation potential through altered co-regulator recruitmentThe winged helix transcription factor HFH-4 is expressed during choroid plexus epithelial development in the mouse embryoHepatic function in a family with a nonsense mutation (R154X) in the hepatocyte nuclear factor-4alpha/MODY1 geneRecruitment of hepatocyte nuclear factor 4 into specific intranuclear compartments depends on tyrosine phosphorylation that affects its DNA-binding and transactivation potentialSuppression of hepatitis B virus core promoter by the nuclear orphan receptor TR4Hepatocyte nuclear factor-4alpha mediates redox sensitivity of inducible nitric-oxide synthase gene transcriptionDissociation of the hepatic phenotype from HNF4 and HNF1alpha expressionPrenatal programming of hepatocyte nuclear factor 4alpha in the rat: A key mechanism in the 'foetal origins of hyperglycaemia'?Functions of HNF1 family members in differentiation of the visceral endoderm cell lineageAn alternative splice variant of the tissue specific transcription factor HNF4alpha predominates in undifferentiated murine cell typesProgenitor cell maintenance requires numb and numblike during mouse neurogenesisComparative analysis of the ATRX promoter and 5' regulatory region reveals conserved regulatory elements which are linked to roles in neurodevelopment, alpha-globin regulation and testicular functionIn vitro culture of embryonic mouse intestinal epithelium: cell differentiation and introduction of reporter genes.Dissecting the transcriptional network of pancreatic islets during development and differentiation.Inhibitor of the tissue-specific transcription factor HNF4, a potential regulator in early Xenopus development.HNF1α inhibition triggers epithelial-mesenchymal transition in human liver cancer cell lines.The HNF-4/HNF-1alpha transactivation cascade regulates gene activity and chromatin structure of the human serine protease inhibitor gene cluster at 14q32.1.A potent far-upstream enhancer in the mouse pro alpha 2(I) collagen gene regulates expression of reporter genes in transgenic micePositive regulation of the vHNF1 promoter by the orphan receptors COUP-TF1/Ear3 and COUP-TFII/Arp1.The activity of the highly inducible mouse phenylalanine hydroxylase gene promoter is dependent upon a tissue-specific, hormone-inducible enhancerThe transcriptional activator hepatocyte nuclear factor 6 regulates liver gene expression.HNF4beta, a new gene of the HNF4 family with distinct activation and expression profiles in oogenesis and embryogenesis of Xenopus laevisHepatocyte nuclear factor 4 expression overcomes repression of the hepatic phenotype in dedifferentiated hepatoma cellsProtein kinase A-dependent phosphorylation modulates DNA-binding activity of hepatocyte nuclear factor 4.Xenobiotic-sensing nuclear receptors involved in drug metabolism: a structural perspectiveComplex genetic control of HDL levels in mice in response to an atherogenic diet. Coordinate regulation of HDL levels and bile acid metabolism.Retinoic acid mediates down-regulation of the alpha-fetoprotein gene through decreased expression of hepatocyte nuclear factors.Characterization of transcriptional regulatory elements in the promoter region of the murine blood coagulation factor VII gene.An enhancer element 6 kb upstream of the mouse HNF4alpha1 promoter is activated by glucocorticoids and liver-enriched transcription factors.Regulatory mechanisms controlling human hepatocyte nuclear factor 4alpha gene expression.Naturally occurring mutations in the human HNF4alpha gene impair the function of the transcription factor to a varying degree.Hepatocyte nuclear factor-4 prevents silencing of hepatocyte nuclear factor-1 expression in hepatoma x fibroblast cell hybrids.TFIIB-directed transcriptional activation by the orphan nuclear receptor hepatocyte nuclear factor 4.Liver-enriched transcription factors uncoupled from expression of hepatic functions in hepatoma cell lines.Hepatocyte nuclear factor-4 mediates apolipoprotein A-IV transcriptional regulation by fatty acid in newborn swine enterocytes.Negative autoregulation of HNF-4alpha gene expression by HNF-4alpha1.Adenovirus-mediated increase of HNF-3 levels stimulates expression of transthyretin and sonic hedgehog, which is associated with F9 cell differentiation toward the visceral endoderm lineage.Three isoforms of a hepatocyte nuclear factor-4 transcription factor with tissue- and stage-specific expression in the adult mosquito.Selective loss of the hepatic phenotype due to the absence of a transcriptional activation pathway.
P2860
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P2860
Tissue-specific regulation of mouse hepatocyte nuclear factor 4 expression
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Tissue-specific regulation of mouse hepatocyte nuclear factor 4 expression
@ast
Tissue-specific regulation of mouse hepatocyte nuclear factor 4 expression
@en
type
label
Tissue-specific regulation of mouse hepatocyte nuclear factor 4 expression
@ast
Tissue-specific regulation of mouse hepatocyte nuclear factor 4 expression
@en
prefLabel
Tissue-specific regulation of mouse hepatocyte nuclear factor 4 expression
@ast
Tissue-specific regulation of mouse hepatocyte nuclear factor 4 expression
@en
P2093
P2860
P356
P1476
Tissue-specific regulation of mouse hepatocyte nuclear factor 4 expression
@en
P2093
J E Darnell
J Mirkovitch
P2860
P304
P356
10.1128/MCB.14.11.7276
P407
P577
1994-11-01T00:00:00Z