NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses. - Wikidata - wikimedia - TriplyDB

NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses.

NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses.

http://www.wikidata.org/entity/Q36670359

about

The CLRX.1/NOD24 (NLRP2P) pseudogene codes a functional negative regulator of NF-κB, pyrin-only protein 4 Innate immunity in the central nervous system Inflammasomes: mechanism of action, role in disease, and therapeutics An Update on PYRIN Domain-Containing Pattern Recognition Receptors: From Immunity to Pathology Control of innate and adaptive immunity by the inflammasome Beyond pattern recognition: NOD-like receptors in dendritic cells.The dendritic cell response to classic, emerging, and homeostatic danger signals. Implications for autoimmunity NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells NLRP3 Inflammasome in Neurological Diseases, from Functions to Therapies The inflammasome NLRs in immunity, inflammation, and associated diseases Inflammasome activation and IL-1β/IL-18 processing are influenced by distinct pathways in microglia NLRP3 inflammasome induces chemotactic immune cell migration to the CNS in experimental autoimmune encephalomyelitis.Chrysophanol inhibits NALP3 inflammasome activation and ameliorates cerebral ischemia/reperfusion in mice A role for cathepsin Z in neuroinflammation provides mechanistic support for an epigenetic risk factor in multiple sclerosis An interferon-β-resistant and NLRP3 inflammasome-independent subtype of EAE with neuronal damage Deregulated inflammasome signaling in disease.Inflammasomes in neuroinflammation and changes in brain function: a focused review.Activated human CD4+CD45RO+ memory T-cells indirectly inhibit NLRP3 inflammasome activation through downregulation of P2X7R signalling.Systemic inflammation and the brain: novel roles of genetic, molecular, and environmental cues as drivers of neurodegeneration.Inflammasomes and autoimmunity Inflammasome activation in obesity-related inflammatory diseases and autoimmunity.Inflammasomes.Inflammasome Activity in Non-Microbial Lung Inflammation.Serum amyloid A activates the NLRP3 inflammasome and promotes Th17 allergic asthma in mice.A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.Neurodegenerative and inflammatory pathway components linked to TNF-α/TNFR1 signaling in the glaucomatous human retina.NLRP3 inflammasome is associated with the response to IFN-β in patients with multiple sclerosis.The inflammasome: pathways linking psychological stress, depression, and systemic illnesses Expanding spectrum of neurologic manifestations in patients with NLRP3 low-penetrance mutations.Neuropathic Pain Phenotype Does Not Involve the NLRP3 Inflammasome and Its End Product Interleukin-1β in the Mice Spared Nerve Injury Model.Immune Complexes Indirectly Suppress the Generation of Th17 Responses In Vivo.NLRP3 deficiency protects from type 1 diabetes through the regulation of chemotaxis into the pancreatic islets.Toll-like receptor (TLR) and inflammasome actions in the central nervous system Regulation of TH17 cell differentiation by innate immune signals.The nod-like receptor, Nlrp12, plays an anti-inflammatory role in experimental autoimmune encephalomyelitis.IL-1 family cytokines trigger sterile inflammatory disease.Interferon-β therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome.NLRP3 Inflammasome and MS/EAE.Autophagy and autoimmunity crosstalks The inflammasome NLRP3 plays a protective role against a viral immunopathological lesion.

P2860

Q24298464-EC1E93CD-64D6-473A-B69F-2E6787AC5C38 Q26858882-AE465F2A-F226-4B56-A299-8E08CD5A507F Q27001186-4307E2F9-ED10-422F-A321-3106E1057D9C Q27004333-08EBCE42-F47A-42E2-833C-61A5DB820759 Q27026744-EB33AE5B-0A75-4DCE-8C81-3EE2A404E3E7 Q27687468-E7EF28D5-8704-440C-B70A-69A4CB8C74B7 Q28384138-4EB07F61-7B42-479F-AA1F-1A4CCE6A4FD7 Q28586719-A95C376F-B690-4833-85C0-D3A8F3FD14FF Q29248417-550F05D7-C516-4443-87E5-CE7FE0302FCA Q29616025-D2868F0F-A22D-4875-8B5A-78762E1056C6 Q30424313-8C116587-8B7B-404B-86FA-57C26BF19F7A Q30519470-DE5A67B5-24FA-495B-902B-4805EEE989DA Q33607932-456D917F-1FF1-4F49-9057-81612656641D Q33655029-1B03563F-D951-421E-87F8-FA4874836AA2 Q33828361-0562589F-B988-4249-9EA1-B87247D99B20 Q34212591-976E4C52-D3B6-4F23-9038-9AECF15290DB Q34299338-B7F12624-395B-4B1D-B16D-400ECBC75470 Q34328201-63B943E7-5078-4AE3-A441-A5ADFF5D477F Q34463760-37D34CA7-6EDE-485A-9B75-D10568A214C4 Q34670542-CFC682EA-FEE1-4AB2-8EE8-77B5F71C747B Q34701729-991DADCB-2A57-4CA5-AE29-92AE338AF215 Q34931052-D755A95F-6DE0-4387-B060-95707159513D Q35020676-9AC7535F-1795-42B0-B21D-9D16C3945A17 Q35058983-7A9ED985-D285-4E6A-9CF6-096092D94C88 Q35350543-A6F185C1-C00F-4843-9B56-7B2F800870CF Q35524470-6E3E3BC9-9A4C-46E5-A1CD-98DB4AA39477 Q35533948-DAEF9DFB-A34F-4C7D-8206-C346F63B152A Q35592049-4D95921F-A055-45E0-810E-A8EB55527634 Q35621217-AC52EE87-8B13-4EB5-B39E-696560780683 Q35720256-4803C7B9-6470-4B3C-B274-267E639BD532 Q35957760-F6B4BFCD-E656-41A3-8DFA-5627369E113E Q36056835-01450649-B9A7-4E9C-99F7-D326C1D9516B Q36058919-17A07FEB-1F32-4A47-9B5C-9A9123863F27 Q36178278-9FAF0C2E-78E8-4ECD-BF16-9D21623DED88 Q36234920-483C3D36-6193-4295-91EE-FA81BE102EFF Q36304279-4131D710-9AE0-4D0E-8386-C6840C77E545 Q36431053-93F1F427-C34E-411E-BFF3-0671A8163557 Q36566053-AB515210-13E2-4931-8477-D681D4E0851F Q36764500-4B7CF0DA-A89F-428E-8909-4D5FF25E9F55 Q36797699-69DF607C-4AD2-4A71-81CF-8E900FAEB174

P2860

NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses.

http://www.wikidata.org/entity/Q36670359

description

2010 nî lūn-bûn

@nan

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

2010年论文

@zh

2010年论文

@zh-cn

name

NLRP3 plays a critical role in ...... iating Th1 and Th17 responses.

@ast

NLRP3 plays a critical role in ...... iating Th1 and Th17 responses.

@en

type

label

NLRP3 plays a critical role in ...... iating Th1 and Th17 responses.

@ast

NLRP3 plays a critical role in ...... iating Th1 and Th17 responses.

@en

prefLabel

NLRP3 plays a critical role in ...... iating Th1 and Th17 responses.

@ast

NLRP3 plays a critical role in ...... iating Th1 and Th17 responses.

@en

P1433

Q36670359-88D33196-CEEC-4D59-9434-AA0ACEB420ED

P1476

Q36670359-A52BAFFC-4682-45A1-B0F7-BA9C68AC0DAC

P2093

Q36670359-279C2ECB-325C-43EE-873F-FD8BA60793D8

Q36670359-396FD652-16A0-4620-87C9-7EF885696313

Q36670359-5AE16B51-2123-4499-BC49-8C777715E735

Q36670359-710ED283-5244-478D-9314-FA9E25D28AF3

Q36670359-8FCCEF3D-513A-41E6-A7F9-8CE037EA6D79

Q36670359-A233CBA9-72B6-4748-931F-09E2F30F02C2

Q36670359-AF1C30DE-BAFD-4156-A39E-7E7953192D54

Q36670359-B9A92DE6-EA97-423B-96F4-B6DA0C97415D

Q36670359-C239AA5B-D8B0-4252-AE08-FB1DD5CB24D9

Q36670359-EFF76130-5889-4F92-B3B4-D2E9FD7C54E4

P2860

Q36670359-012C6F82-C9B4-41DF-8143-35ED82A9720F

Q36670359-07508F1E-8199-43F7-961F-2518F7BB3968

Q36670359-07F6CCE7-69F3-4BCD-A728-0766B4E2B28E

Q36670359-11977612-F4C1-46CC-B813-A8EA7ADADD84

Q36670359-15FD69F7-E7E7-43BD-A030-4C2C9CA3FE41

Q36670359-16ECCFD6-711C-422F-8A5B-11B4E1D52F6B

Q36670359-22F03FBF-564E-4554-80EF-ECA44F578B80

Q36670359-25EFEF3F-9EDC-484D-9FCC-43E9334357FE

Q36670359-2816EDB8-23EC-4D69-90A3-C500D0A13C2C

Q36670359-3314B5C4-2FC4-4161-AB91-27BAC5E3F8A4

P304

Q36670359-D7A76F86-BAD5-4B1D-BA5C-EBF5E064356E

P31

Q36670359-8E85DA45-553E-4D58-AFF4-538636A18577

P356

Q36670359-F3162F13-7E7C-4BAE-8CCB-1333A8F89DD9

P407

Q36670359-65C2EA65-34D7-444F-BAD3-CC8B52DB7C87

P433

Q36670359-398C77A0-D2CE-487B-8588-715A287B3FAC

P478

Q36670359-1E727E80-7C2D-4314-86BA-DD24DB2FF97E

P577

Q36670359-8378F4D8-F72D-4504-88D1-7DAB3A15E889

P5875

Q36670359-FCA1A6B9-39CB-4FA3-812F-BB1D2119959F

P698

Q36670359-46E88CE2-737A-4EA5-80CF-00AF353FC886

P921

Q36670359-0C4706D3-296C-46B9-B08A-1A544A478C1E

P932

Q36670359-5579D9FF-1264-4594-AE05-90DA1B6ADA17

P356

JIMMUNOL.0904145

P1433

Journal of Immunology

P1476

NLRP3 plays a critical role in ...... iating Th1 and Th17 responses.

@en

P2093

Denis Gris

http://www.w3.org/2001/XMLSchema#string

Haitao Wen

http://www.w3.org/2001/XMLSchema#string

Heather A Iocca

http://www.w3.org/2001/XMLSchema#string

Jenny P-Y Ting

http://www.w3.org/2001/XMLSchema#string

Max Huang

http://www.w3.org/2001/XMLSchema#string

Monika Schneider

http://www.w3.org/2001/XMLSchema#string

Pavel Gris

http://www.w3.org/2001/XMLSchema#string

Robin R Craven

http://www.w3.org/2001/XMLSchema#string

Stephen D Miller

http://www.w3.org/2001/XMLSchema#string

Zhengmao Ye

http://www.w3.org/2001/XMLSchema#string

P2860

The NLR gene family: a standard nomenclature

IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation

Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells

Analyzing real-time PCR data by the comparative C(T) method

Cryopyrin activates the inflammasome in response to toxins and ATP

Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA

T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

Abnormal T cell activation caused by the imbalance of the IL-1/IL-1R antagonist system is responsible for the development of experimental autoimmune encephalomyelitis

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1

P304

974-981

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.4049/JIMMUNOL.0904145

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

185

http://www.w3.org/2001/XMLSchema#string

P577

2010-06-23T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

44698321

http://www.w3.org/2001/XMLSchema#string

P698

20574004

http://www.w3.org/2001/XMLSchema#string

P921

experimental autoimmune encephalomyelitis

P932

3593010

http://www.w3.org/2001/XMLSchema#string