NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses.
about
The CLRX.1/NOD24 (NLRP2P) pseudogene codes a functional negative regulator of NF-κB, pyrin-only protein 4Innate immunity in the central nervous systemInflammasomes: mechanism of action, role in disease, and therapeuticsAn Update on PYRIN Domain-Containing Pattern Recognition Receptors: From Immunity to PathologyControl of innate and adaptive immunity by the inflammasomeBeyond pattern recognition: NOD-like receptors in dendritic cells.The dendritic cell response to classic, emerging, and homeostatic danger signals. Implications for autoimmunityNLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cellsNLRP3 Inflammasome in Neurological Diseases, from Functions to TherapiesThe inflammasome NLRs in immunity, inflammation, and associated diseasesInflammasome activation and IL-1β/IL-18 processing are influenced by distinct pathways in microgliaNLRP3 inflammasome induces chemotactic immune cell migration to the CNS in experimental autoimmune encephalomyelitis.Chrysophanol inhibits NALP3 inflammasome activation and ameliorates cerebral ischemia/reperfusion in miceA role for cathepsin Z in neuroinflammation provides mechanistic support for an epigenetic risk factor in multiple sclerosisAn interferon-β-resistant and NLRP3 inflammasome-independent subtype of EAE with neuronal damageDeregulated inflammasome signaling in disease.Inflammasomes in neuroinflammation and changes in brain function: a focused review.Activated human CD4+CD45RO+ memory T-cells indirectly inhibit NLRP3 inflammasome activation through downregulation of P2X7R signalling.Systemic inflammation and the brain: novel roles of genetic, molecular, and environmental cues as drivers of neurodegeneration.Inflammasomes and autoimmunityInflammasome activation in obesity-related inflammatory diseases and autoimmunity.Inflammasomes.Inflammasome Activity in Non-Microbial Lung Inflammation.Serum amyloid A activates the NLRP3 inflammasome and promotes Th17 allergic asthma in mice.A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.Neurodegenerative and inflammatory pathway components linked to TNF-α/TNFR1 signaling in the glaucomatous human retina.NLRP3 inflammasome is associated with the response to IFN-β in patients with multiple sclerosis.The inflammasome: pathways linking psychological stress, depression, and systemic illnessesExpanding spectrum of neurologic manifestations in patients with NLRP3 low-penetrance mutations.Neuropathic Pain Phenotype Does Not Involve the NLRP3 Inflammasome and Its End Product Interleukin-1β in the Mice Spared Nerve Injury Model.Immune Complexes Indirectly Suppress the Generation of Th17 Responses In Vivo.NLRP3 deficiency protects from type 1 diabetes through the regulation of chemotaxis into the pancreatic islets.Toll-like receptor (TLR) and inflammasome actions in the central nervous systemRegulation of TH17 cell differentiation by innate immune signals.The nod-like receptor, Nlrp12, plays an anti-inflammatory role in experimental autoimmune encephalomyelitis.IL-1 family cytokines trigger sterile inflammatory disease.Interferon-β therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome.NLRP3 Inflammasome and MS/EAE.Autophagy and autoimmunity crosstalksThe inflammasome NLRP3 plays a protective role against a viral immunopathological lesion.
P2860
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P2860
NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
NLRP3 plays a critical role in ...... iating Th1 and Th17 responses.
@ast
NLRP3 plays a critical role in ...... iating Th1 and Th17 responses.
@en
type
label
NLRP3 plays a critical role in ...... iating Th1 and Th17 responses.
@ast
NLRP3 plays a critical role in ...... iating Th1 and Th17 responses.
@en
prefLabel
NLRP3 plays a critical role in ...... iating Th1 and Th17 responses.
@ast
NLRP3 plays a critical role in ...... iating Th1 and Th17 responses.
@en
P2093
P2860
P356
P1476
NLRP3 plays a critical role in ...... iating Th1 and Th17 responses.
@en
P2093
Denis Gris
Haitao Wen
Heather A Iocca
Jenny P-Y Ting
Monika Schneider
Pavel Gris
Robin R Craven
Stephen D Miller
Zhengmao Ye
P2860
P304
P356
10.4049/JIMMUNOL.0904145
P407
P577
2010-06-23T00:00:00Z