RNA interference targeting CUG repeats in a mouse model of myotonic dystrophy. - Wikidata - wikimedia - TriplyDB

RNA interference targeting CUG repeats in a mouse model of myotonic dystrophy.

RNA interference targeting CUG repeats in a mouse model of myotonic dystrophy.

http://www.wikidata.org/entity/Q36673701

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RNA-Binding Proteins: Splicing Factors and Disease Noncoding RNAs: emerging players in muscular dystrophies Oral administration of erythromycin decreases RNA toxicity in myotonic dystrophy Cell membrane integrity in myotonic dystrophy type 1: implications for therapy Studying a Drug-like, RNA-Focused Small Molecule Library Identifies Compounds That Inhibit RNA Toxicity in Myotonic Dystrophy MBNL proteins and their target RNAs, interaction and splicing regulation.Developing bivalent ligands to target CUG triplet repeats, the causative agent of myotonic dystrophy type 1.Short antisense-locked nucleic acids (all-LNAs) correct alternative splicing abnormalities in myotonic dystrophy.Meeting Report: New Directions in the Biology and Disease of Skeletal Muscle 2014 Therapeutic impact of systemic AAV-mediated RNA interference in a mouse model of myotonic dystrophy.Cooperation meets competition in microRNA-mediated DMPK transcript regulation.Engineering Duplex RNAs for Challenging Targets: Recognition of GGGGCC/CCCCGG Repeats at the ALS/FTD C9orf72 Locus A flow cytometry-based screen identifies MBNL1 modulators that rescue splicing defects in myotonic dystrophy type I.Tibialis anterior muscle needle biopsy and sensitive biomolecular methods: a useful tool in myotonic dystrophy type 1 Design and analysis of effects of triplet repeat oligonucleotides in cell models for myotonic dystrophy Targeting deregulated AMPK/mTORC1 pathways improves muscle function in myotonic dystrophy type I.Reduction of Huntington's Disease RNA Foci by CAG Repeat-Targeting Reagents.Gene-based therapies of neuromuscular disorders: an update and the pivotal role of patient organizations in their discovery and implementation.Developmental insights into the pathology of and therapeutic strategies for DM1: Back to the basics.Myotonic dystrophy: approach to therapy.Structures of RNA repeats associated with neurological diseases.Biomolecular diagnosis of myotonic dystrophy type 2: a challenging approach.RNA biology of disease-associated microsatellite repeat expansions.Small molecule kinase inhibitors alleviate different molecular features of myotonic dystrophy type 1.Hybrid splicing minigene and antisense oligonucleotides as efficient tools to determine functional protein/RNA interactions.MBNL expression in autoregulatory feedback loops.c9RAN translation: a potential therapeutic target for the treatment of amyotrophic lateral sclerosis and frontotemporal dementia.RNAi-mediated knockdown of IKK1 in transgenic mice using a transgenic construct containing the human H1 promoter.Cells of Matter-In Vitro Models for Myotonic Dystrophy.Small Molecules Which Improve Pathogenesis of Myotonic Dystrophy Type 1.

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P2860

RNA interference targeting CUG repeats in a mouse model of myotonic dystrophy.

http://www.wikidata.org/entity/Q36673701

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

RNA interference targeting CUG repeats in a mouse model of myotonic dystrophy.

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RNA interference targeting CUG repeats in a mouse model of myotonic dystrophy.

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type

label

RNA interference targeting CUG repeats in a mouse model of myotonic dystrophy.

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RNA interference targeting CUG repeats in a mouse model of myotonic dystrophy.

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prefLabel

RNA interference targeting CUG repeats in a mouse model of myotonic dystrophy.

@ast

RNA interference targeting CUG repeats in a mouse model of myotonic dystrophy.

@en

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Molecular Therapy

P1476

RNA interference targeting CUG repeats in a mouse model of myotonic dystrophy.

@en

P2093

Charles A Thornton

http://www.w3.org/2001/XMLSchema#string

Krzysztof Sobczak

http://www.w3.org/2001/XMLSchema#string

Thurman M Wheeler

http://www.w3.org/2001/XMLSchema#string

Wenli Wang

http://www.w3.org/2001/XMLSchema#string

P2860

Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy

Inactivation of hnRNP K by expanded intronic AUUCU repeat induces apoptosis via translocation of PKCdelta to mitochondria in spinocerebellar ataxia 10

Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS

Correction of ClC-1 splicing eliminates chloride channelopathy and myotonia in mouse models of myotonic dystrophy

Myotonic dystrophy type 2 caused by a CCTG expansion in intron 1 of ZNF9

MBNL1 is the primary determinant of focus formation and aberrant insulin receptor splicing in DM1

Trinucleotide Repeat Disorders

Molecular basis of myotonic dystrophy: expansion of a trinucleotide (CTG) repeat at the 3' end of a transcript encoding a protein kinase family member.

Expanded CUG repeats trigger aberrant splicing of ClC-1 chloride channel pre-mRNA and hyperexcitability of skeletal muscle in myotonic dystrophy.

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380-387

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scholarly article

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10.1038/MT.2012.222

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2

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21

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2012-11-27T00:00:00Z

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23183533

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3594017

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