Alpha1 soluble guanylyl cyclase (sGC) splice forms as potential regulators of human sGC activity
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RNA splicing in regulation of nitric oxide receptor soluble guanylyl cyclaseInterfacial residues promote an optimal alignment of the catalytic center in human soluble guanylate cyclase: heterodimerization is required but not sufficient for activity.The amino-terminus of nitric oxide sensitive guanylyl cyclase α₁ does not affect dimerization but influences subcellular localizationAlternative splicing of the guanylyl cyclase-A receptor modulates atrial natriuretic peptide signalingRole of soluble guanylyl cyclase-cyclic GMP signaling in tumor cell proliferation.Volume overload induces differential spatiotemporal regulation of myocardial soluble guanylyl cyclase in eccentric hypertrophy and heart failureThe fibrate gemfibrozil is a NO- and haem-independent activator of soluble guanylyl cyclase: in vitro studies.Nitric oxide and heat shock protein 90 activate soluble guanylate cyclase by driving rapid change in its subunit interactions and heme content.Hydrogen peroxide alters splicing of soluble guanylyl cyclase and selectively modulates expression of splicing regulators in human cancer cells.Alternative splicing impairs soluble guanylyl cyclase function in aortic aneurysmNitric oxide receptor soluble guanylyl cyclase undergoes splicing regulation in differentiating human embryonic cells.Restoring soluble guanylyl cyclase expression and function blocks the aggressive course of glioma.Nitric oxide-cyclic GMP signaling in stem cell differentiationYC-1 binding to the β subunit of soluble guanylyl cyclase overcomes allosteric inhibition by the α subunit.The G-protein regulator LGN modulates the activity of the NO receptor soluble guanylate cyclaseRole of sGC-dependent NO signalling and myocardial infarction risk.Structure and Activation of Soluble Guanylyl Cyclase, the Nitric Oxide Sensor.Truncated IRAG variants modulate cGMP-mediated inhibition of human colonic smooth muscle cell contraction.A diseasome cluster-based drug repurposing of soluble guanylate cyclase activators from smooth muscle relaxation to direct neuroprotection.Endothelial dysfunction promotes the transition from compensatory renal hypertrophy to kidney injury after unilateral nephrectomy in mice.
P2860
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P2860
Alpha1 soluble guanylyl cyclase (sGC) splice forms as potential regulators of human sGC activity
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Alpha1 soluble guanylyl cyclas ...... gulators of human sGC activity
@ast
Alpha1 soluble guanylyl cyclas ...... gulators of human sGC activity
@en
type
label
Alpha1 soluble guanylyl cyclas ...... gulators of human sGC activity
@ast
Alpha1 soluble guanylyl cyclas ...... gulators of human sGC activity
@en
prefLabel
Alpha1 soluble guanylyl cyclas ...... gulators of human sGC activity
@ast
Alpha1 soluble guanylyl cyclas ...... gulators of human sGC activity
@en
P2093
P2860
P356
P1476
Alpha1 soluble guanylyl cyclas ...... gulators of human sGC activity
@en
P2093
Anthony Thomas
Elena P Bogatenkova
Emil Martin
Filip Jelen
Iraida G Sharina
P2860
P304
15104-15113
P356
10.1074/JBC.M710269200
P407
P50
P577
2008-04-01T00:00:00Z