Phosphorylation of splicing factor SF1 on Ser20 by cGMP-dependent protein kinase regulates spliceosome assembly
about
Nuclear relocalization of the pre-mRNA splicing factor PSF during apoptosis involves hyperphosphorylation, masking of antigenic epitopes, and changes in protein interactionsU2AF-homology motif interactions are required for alternative splicing regulation by SPF45Phosphorylation of septin 3 on Ser-91 by cGMP-dependent protein kinase-I in nerve terminalsThe FCP1 phosphatase interacts with RNA polymerase II and with MEP50 a component of the methylosome complex involved in the assembly of snRNPSAM68 regulates neuronal activity-dependent alternative splicing of neurexin-1Human branch point consensus sequence is yUnAySplicing factors SF1 and U2AF associate in extraspliceosomal complexesDimerization and protein binding specificity of the U2AF homology motif of the splicing factor Puf60Structure, phosphorylation and U2AF65 binding of the N-terminal domain of splicing factor 1 during 3'-splice site recognitionStructure of Phosphorylated SF1 Bound to U2AF65 in an Essential Splicing Factor ComplexCancer-relevant Splicing Factor CAPERĪ± Engages the Essential Splicing Factor SF3b155 in a Specific Ternary ComplexNO activation of fos promoter elements requires nuclear translocation of G-kinase I and CREB phosphorylation but is independent of MAP kinase activationcGMP-dependent protein kinase I beta physically and functionally interacts with the transcriptional regulator TFII-IThe protein phosphatase-1 regulator NIPP1 is also a splicing factor involved in a late step of spliceosome assemblyPhosphorylation-dependent interaction between the splicing factors SAP155 and NIPP1Alternative splicing regulation by interaction of phosphatase PP2Cgamma with nucleic acid-binding protein YB-1Phosphorylation of S776 and 14-3-3 binding modulate ataxin-1 interaction with splicing factorsThe Drosophila splicing factor PSI is phosphorylated by casein kinase II and tousled-like kinasePhosphorylation of a new brain-specific septin, G-septin, by cGMP-dependent protein kinaseFormation of nuclear bodies by the lncRNA Gomafu-associating proteins Celf3 and SF1Specific Ser-Pro phosphorylation by the RNA-recognition motif containing kinase KIS.Analysis of mutant phenotypes and splicing defects demonstrates functional collaboration between the large and small subunits of the essential splicing factor U2AF in vivo.Kinetic role for mammalian SF1/BBP in spliceosome assembly and function after polypyrimidine tract recognition by U2AF.GREBP, a cGMP-response element-binding protein repressing the transcription of natriuretic peptide receptor 1 (NPR1/GCA).cGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action.Splicing factor SF1 from Drosophila and Caenorhabditis: presence of an N-terminal RS domain and requirement for viabilityHtra2-beta 1 stimulates an exonic splicing enhancer and can restore full-length SMN expression to survival motor neuron 2 (SMN2)Structural basis for regulation of RNA-binding proteins by phosphorylation.Major phosphorylation of SF1 on adjacent Ser-Pro motifs enhances interaction with U2AF65.Multiple U2AF65 binding sites within SF3b155: thermodynamic and spectroscopic characterization of protein-protein interactions among pre-mRNA splicing factors.Alpha1 soluble guanylyl cyclase (sGC) splice forms as potential regulators of human sGC activityActivation of ETB receptors regulates the abundance of ET-1 mRNA in vascular endothelial cells.The Proteomic Profile of Deleted in Breast Cancer 1 (DBC1) Interactions Points to a Multifaceted Regulation of Gene ExpressioncGMP-dependent protein kinase anchoring by IRAG regulates its nuclear translocation and transcriptional activityPrediction of functional phosphorylation sites by incorporating evolutionary informationDifferent requirements of the kinase and UHM domains of KIS for its nuclear localization and binding to splicing factors.CD82 suppresses CD44 alternative splicing-dependent melanoma metastasis by mediating U2AF2 ubiquitination and degradationSplicing factor 1 modulates dietary restriction and TORC1 pathway longevity in C. elegans.Diverse regulation of 3' splice site usage.SF1 Phosphorylation Enhances Specific Binding to U2AF65 and Reduces Binding to 3'-Splice-Site RNA.
P2860
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P2860
Phosphorylation of splicing factor SF1 on Ser20 by cGMP-dependent protein kinase regulates spliceosome assembly
description
1999 nĆ® lÅ«n-bĆ»n
@nan
1999 Õ©ÕøÖÕ”ÕÆÕ”Õ¶Õ« ÕÕ£ÕøÕ½ÕæÕøÕ½Õ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕøÖÕ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ ÕµÖ
Õ¤ÕøÖÕ”Õ®
@hyw
1999 Õ©Õ¾Õ”ÕÆÕ”Õ¶Õ« Ö
Õ£ÕøÕ½ÕæÕøÕ½Õ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕ¾Õ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ Õ°ÕøÕ¤Õ¾Õ”Õ®
@hy
1999幓ć®č«ę
@ja
1999幓č«ę
@yue
1999幓č«ę
@zh-hant
1999幓č«ę
@zh-hk
1999幓č«ę
@zh-mo
1999幓č«ę
@zh-tw
1999幓č®ŗę
@wuu
name
Phosphorylation of splicing fa ...... regulates spliceosome assembly
@ast
Phosphorylation of splicing fa ...... regulates spliceosome assembly
@en
Phosphorylation of splicing fa ...... regulates spliceosome assembly
@nl
type
label
Phosphorylation of splicing fa ...... regulates spliceosome assembly
@ast
Phosphorylation of splicing fa ...... regulates spliceosome assembly
@en
Phosphorylation of splicing fa ...... regulates spliceosome assembly
@nl
prefLabel
Phosphorylation of splicing fa ...... regulates spliceosome assembly
@ast
Phosphorylation of splicing fa ...... regulates spliceosome assembly
@en
Phosphorylation of splicing fa ...... regulates spliceosome assembly
@nl
P2093
P3181
P356
P1433
P1476
Phosphorylation of splicing fa ...... regulates spliceosome assembly
@en
P2093
P J Milburn
P J Robinson
S Bruderer
P304
P3181
P356
10.1093/EMBOJ/18.16.4549
P407
P577
1999-08-16T00:00:00Z