A patient-derived stem cell model of hereditary spastic paraplegia with SPAST mutations
about
Bridging the gap between basic and applied biology: towards preclinical translationEmerging functional cross-talk between the Keap1-Nrf2 system and mitochondriaLow dose tubulin-binding drugs rescue peroxisome trafficking deficit in patient-derived stem cells in Hereditary Spastic Paraplegia.Pharmacologic rescue of axon growth defects in a human iPSC model of hereditary spastic paraplegia SPG3A.Patient-derived olfactory mucosa for study of the non-neuronal contribution to amyotrophic lateral sclerosis pathology.Patient-derived stem cells: pathways to drug discovery for brain diseases.Mechanism of impaired microtubule-dependent peroxisome trafficking and oxidative stress in SPAST-mutated cells from patients with Hereditary Spastic Paraplegia.Loss of spastin function results in disease-specific axonal defects in human pluripotent stem cell-based models of hereditary spastic paraplegia.Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons.Human-induced pluripotent stem cells pave the road for a better understanding of motor neuron disease.New splicing variants of mitochondrial Rho GTPase-1 (Miro1) transport peroxisomes.Mutant spastin proteins promote deficits in axonal transport through an isoform-specific mechanism involving casein kinase 2 activation.A Patient-Specific Stem Cell Model to Investigate the Neurological Phenotype Observed in Ataxia-Telangiectasia.Clinical spectrum and genetic landscape for hereditary spastic paraplegias in China.Patient-Derived Stem Cell Models in HSP: Disease Modelling and Drug Discovery
P2860
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P2860
A patient-derived stem cell model of hereditary spastic paraplegia with SPAST mutations
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
A patient-derived stem cell model of hereditary spastic paraplegia with SPAST mutations
@ast
A patient-derived stem cell model of hereditary spastic paraplegia with SPAST mutations
@en
type
label
A patient-derived stem cell model of hereditary spastic paraplegia with SPAST mutations
@ast
A patient-derived stem cell model of hereditary spastic paraplegia with SPAST mutations
@en
prefLabel
A patient-derived stem cell model of hereditary spastic paraplegia with SPAST mutations
@ast
A patient-derived stem cell model of hereditary spastic paraplegia with SPAST mutations
@en
P2093
P2860
P50
P356
P1476
A patient-derived stem cell model of hereditary spastic paraplegia with SPAST mutations
@en
P2093
Bernadette Bellette
Carolyn M Sue
David Veivers
Gautam Wali
Greger Abrahamsen
Jyothy Raju
Ratneswary Sutharsan
Yongjun Fan
P2860
P304
P356
10.1242/DMM.010884
P577
2012-12-20T00:00:00Z