A truncated P2X7 receptor variant (P2X7-j) endogenously expressed in cervical cancer cells antagonizes the full-length P2X7 receptor through hetero-oligomerization
about
Molecular and functional properties of P2X receptors--recent progress and persisting challengesPurinergic signalling and cancerConserved ectodomain cysteines are essential for rat P2X7 receptor traffickingPurinergic signalling in the reproductive system in health and diseaseThe two-hit hypothesis for neuroinflammation: role of exogenous ATP in modulating inflammation in the brainThe C-terminus of human nucleotide receptor P2X7 is critical for receptor oligomerization and N-linked glycosylationActivation of P2X(7)-mediated apoptosis Inhibits DMBA/TPA-induced formation of skin papillomas and cancer in mice.Corneal epithelium expresses a variant of P2X(7) receptor in health and diseaseTrophic activity of human P2X7 receptor isoforms A and B in osteosarcoma.Haplotypes of P2RX7 gene polymorphisms are associated with both cold pain sensitivity and analgesic effect of fentanyl.MicroRNAs miR-186 and miR-150 down-regulate expression of the pro-apoptotic purinergic P2X7 receptor by activation of instability sites at the 3'-untranslated region of the gene that decrease steady-state levels of the transcriptmiR-150 promotes human breast cancer growth and malignant behavior by targeting the pro-apoptotic purinergic P2X7 receptorExpression, assembly and function of novel C-terminal truncated variants of the mouse P2X7 receptor: re-evaluation of P2X7 knockoutsCo-Expression of Wild-Type P2X7R with Gln460Arg Variant Alters Receptor FunctionRhinovirus-induced IL-1β release from bronchial epithelial cells is independent of functional P2X7Reversible inhibition of Chlamydia trachomatis infection in epithelial cells due to stimulation of P2X(4) receptors.The P2X7 receptor: a novel biomarker of uterine epithelial cancers.Decreased expression of P2X7 in endometrial epithelial pre-cancerous and cancer cells.Regulation by P2X7: epithelial migration and stromal organization in the cornea.Assembly and trafficking of P2X purinergic receptors (Review).Cell signaling via the P2X(7) nucleotide receptor: linkage to ROS production, gene transcription, and receptor traffickingAttenuated, flow-induced ATP release contributes to absence of flow-sensitive, purinergic Cai2+ signaling in human ADPKD cyst epithelial cellsP2X(7) receptor expression is decreased in epithelial cancer cells of ectodermal, uro-genital sinus, and distal paramesonephric duct origin.Regulation of P2X(7) gene transcription.P2X7-mediated chemoprevention of epithelial cancers.Functional variant of the P2X7 receptor gene is associated with human papillomavirus-16 positive cervical squamous cell carcinoma.C terminus of the P2X7 receptor: treasure hunting.Insulin-degrading enzyme is exported via an unconventional protein secretion pathway.Fluorescent dyes as a reliable tool in P2X7 receptor-associated pore studies.P2X7 purinoceptor alterations in dystrophic mdx mouse muscles: relationship to pathology and potential target for treatmentIdentification and characterization of a novel variant of the human P2X(7) receptor resulting in gain of function.Diadenosine homodinucleotide products of ADP-ribosyl cyclases behave as modulators of the purinergic receptor P2X7.A functional P2X7 splice variant with an alternative transmembrane domain 1 escapes gene inactivation in P2X7 knock-out mice.Hyperthermia and associated changes in membrane fluidity potentiate P2X7 activation to promote tumor cell death.Characterisation of the R276A gain-of-function mutation in the ectodomain of murine P2X7Hyperosmotic stress induces ATP release and changes in P2X7 receptor levels in human corneal and conjunctival epithelial cells.Purinergic Signalling: Therapeutic Developments.Regulation of activity of P2X7 receptor by its splice variants in cultured mouse astrocytes.Lack of neuroprotection in the absence of P2X7 receptors in toxin-induced animal models of Parkinson's disease.A phase I clinical trial demonstrates that nfP2X7 -targeted antibodies provide a novel, safe and tolerable topical therapy for basal cell carcinoma.
P2860
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P2860
A truncated P2X7 receptor variant (P2X7-j) endogenously expressed in cervical cancer cells antagonizes the full-length P2X7 receptor through hetero-oligomerization
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
A truncated P2X7 receptor vari ...... through hetero-oligomerization
@ast
A truncated P2X7 receptor vari ...... through hetero-oligomerization
@en
type
label
A truncated P2X7 receptor vari ...... through hetero-oligomerization
@ast
A truncated P2X7 receptor vari ...... through hetero-oligomerization
@en
prefLabel
A truncated P2X7 receptor vari ...... through hetero-oligomerization
@ast
A truncated P2X7 receptor vari ...... through hetero-oligomerization
@en
P2093
P2860
P356
P1476
A truncated P2X7 receptor vari ...... through hetero-oligomerization
@en
P2093
George I Gorodeski
Lingying Zhou
Liqin Wang
Ying-Hong Feng
P2860
P304
17228-17237
P356
10.1074/JBC.M602999200
P407
P577
2006-04-18T00:00:00Z