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CSIG inhibits PTEN translation in replicative senescenceA clinical scoring system for selection of patients for PTEN mutation testing is proposed on the basis of a prospective study of 3042 probandsActivation of the PI3K pathway in cancer through inhibition of PTEN by exchange factor P-REX2aMolecular characterizations of glioblastoma, targeted therapy, and clinical results to dateFISH analysis of 107 prostate cancers shows that PTEN genomic deletion is associated with poor clinical outcome.Role of NMDA Receptor-Mediated Glutamatergic Signaling in Chronic and Acute NeuropathologiesA secreted PTEN phosphatase that enters cells to alter signaling and survivalHCV infection-associated hepatocellular carcinoma in humanized miceA novel PTEN/mutant p53/c-Myc/Bcl-XL axis mediates context-dependent oncogenic effects of PTEN with implications for cancer prognosis and therapyInteractions between PTEN and receptor tyrosine kinase pathways and their implications for glioma therapyEvidence of ultraviolet type mutations in xeroderma pigmentosum melanomas.A transcriptomic computational analysis of mastic oil-treated Lewis lung carcinomas reveals molecular mechanisms targeting tumor cell growth and survivalPlk1 protein phosphorylates phosphatase and tensin homolog (PTEN) and regulates its mitotic activity during the cell cycleSimvastatin induces derepression of PTEN expression via NFkappaB to inhibit breast cancer cell growth.Fish oil targets PTEN to regulate NFkappaB for downregulation of anti-apoptotic genes in breast tumor growth.A high-content screening (HCS) assay for the identification of chemical inducers of PML oncogenic domains (PODs).Engineering ePTEN, an enhanced PTEN with increased tumor suppressor activities.Different conformations of phosphatase and tensin homolog, deleted on chromosome 10 (PTEN) protein within the nucleus and cytoplasm of neuronsDifferential subcellular and extracellular localisations of proteins required for insulin-like growth factor- and extracellular matrix-induced signalling events in breast cancer progressionThe PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models.PTEN interacts with histone H1 and controls chromatin condensation.p34 is a novel regulator of the oncogenic behavior of NEDD4-1 and PTEN.Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair.Ubiquitin becomes ubiquitous in cancer: emerging roles of ubiquitin ligases and deubiquitinases in tumorigenesis and as therapeutic targets.Overexpression of 4EBP1, p70S6K, Akt1 or Akt2 differentially promotes Coxsackievirus B3-induced apoptosis in HeLa cells.CREB is a novel nuclear target of PTEN phosphatase.Mechanism of human PTEN localization revealed by heterologous expression in Dictyostelium.SIRT1 deficiency downregulates PTEN/JNK/FOXO1 pathway to block reactive oxygen species-induced apoptosis in mouse embryonic stem cells.PTEN: Multiple Functions in Human Malignant TumorsRelevance and therapeutic possibility of PTEN-long in renal cell carcinoma.MiR-486 regulates lactation and targets the PTEN gene in cow mammary glands.Protein tyrosine phosphatases PTP-1B, SHP-2, and PTEN facilitate Rb/E2F-associated apoptotic signaling.Catalysis by the tumor-suppressor enzymes PTEN and PTEN-L.Novel targeting of PEGylated liposomes for codelivery of TGF-β1 siRNA and four antitubercular drugs to human macrophages for the treatment of mycobacterial infection: a quantitative proteomic study.Genetic diversity in melanoma metastases from a patient with xeroderma pigmentosum.Sprouty2, PTEN, and PP2A interact to regulate prostate cancer progression.PTEN, more than the AKT pathway.The TORrid affairs of viruses: effects of mammalian DNA viruses on the PI3K-Akt-mTOR signalling pathway.Portrait of PTEN: messages from mutant mice.Protein tyrosine phosphatases: dual-specificity phosphatases in health and disease.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
PTEN enters the nuclear age.
@ast
PTEN enters the nuclear age.
@en
type
label
PTEN enters the nuclear age.
@ast
PTEN enters the nuclear age.
@en
prefLabel
PTEN enters the nuclear age.
@ast
PTEN enters the nuclear age.
@en
P1433
P1476
PTEN enters the nuclear age.
@en
P2093
Suzanne J Baker
P356
10.1016/J.CELL.2006.12.023
P407
P577
2007-01-01T00:00:00Z