A secreted PTEN phosphatase that enters cells to alter signaling and survival - Wikidata - wikimedia - TriplyDB

A secreted PTEN phosphatase that enters cells to alter signaling and survival

A secreted PTEN phosphatase that enters cells to alter signaling and survival

http://www.wikidata.org/entity/Q28292188

about

Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function Focus on PTEN Regulation Balancing Proliferation and Connectivity in PTEN-associated Autism Spectrum Disorder Why is start codon selection so precise in eukaryotes?Wrecked regulation of intrinsically disordered proteins in diseases: pathogenicity of deregulated regulators Methodological aspects of the molecular and histological study of prostate cancer: focus on PTEN Subcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurological disorders Therapeutic targeting of cancers with loss of PTEN function.Warburg effect, hexokinase-II, and radioresistance of laryngeal carcinoma PTENα, a PTEN isoform translated through alternative initiation, regulates mitochondrial function and energy metabolism The intrinsically disordered tails of PTEN and PTEN-L have distinct roles in regulating substrate specificity and membrane activity The PTEN Long N-tail is intrinsically disordered: increased viability for PTEN therapy A functional dissection of PTEN N-terminus: implications in PTEN subcellular targeting and tumor suppressor activity Reference sequence (RefSeq) database at NCBI: current status, taxonomic expansion, and functional annotation Computational approach for calculating the probability of eukaryotic translation initiation from ribo-seq data that takes into account leaky scanning.Ecto-protein kinases and phosphatases: an emerging field for translational medicine.New frontiers in translational control of the cancer genome Pathological unfoldomics of uncontrolled chaos: intrinsically disordered proteins and human diseases PTEN redundancy: overexpressing lpten, a homolog of Dictyostelium discoideum ptenA, the ortholog of human PTEN, rescues all behavioral defects of the mutant ptenA-PTEN: Multiple Functions in Human Malignant Tumors Relevance and therapeutic possibility of PTEN-long in renal cell carcinoma.Lung neuroendocrine tumors: correlation of ubiquitinylation and sumoylation with nucleo-cytosolic partitioning of PTEN.A unified nomenclature and amino acid numbering for human PTEN.Conformational stability and catalytic activity of PTEN variants linked to cancers and autism spectrum disorders.Ectokinases as novel cancer markers and drug targets in cancer therapy.Catalysis by the tumor-suppressor enzymes PTEN and PTEN-L.Proteomic database mining opens up avenues utilizing extracellular protein phosphorylation for novel therapeutic applications.Oxygen and glucose deprivation induces widespread alterations in mRNA translation within 20 minutes MicroRNA Expression Profile of Neural Progenitor-Like Cells Derived from Rat Bone Marrow Mesenchymal Stem Cells under the Influence of IGF-1, bFGF and EGF.Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo The Optimization of Soluble PTEN Expression in Escherichia coli Intracellular delivery of the PTEN protein using cationic lipidoids for cancer therapy.A PTEN translational isoform has PTEN-like activity.Histone demethylase RBP2 promotes malignant progression of gastric cancer through TGF-β1-(p-Smad3)-RBP2-E-cadherin-Smad3 feedback circuit.AIF inhibits tumor metastasis by protecting PTEN from oxidation.Semi-permeable Diffusion Barriers Enhance Patterning Robustness in the C. elegans Germline.Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth.Systematic analysis of the PTEN 5' leader identifies a major AUU initiated proteoform.Defining the interorgan communication network: systemic coordination of organismal cellular processes under homeostasis and localized stress.TISdb: a database for alternative translation initiation in mammalian cells.

P2860

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P2860

A secreted PTEN phosphatase that enters cells to alter signaling and survival

http://www.wikidata.org/entity/Q28292188

description

2013 nî lūn-bûn

@nan

2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年学术文章

@wuu

2013年学术文章

@zh-cn

2013年学术文章

@zh-hans

2013年学术文章

@zh-my

2013年学术文章

@zh-sg

2013年學術文章

@yue

name

A secreted PTEN phosphatase that enters cells to alter signaling and survival

@ast

A secreted PTEN phosphatase that enters cells to alter signaling and survival

@en

A secreted PTEN phosphatase that enters cells to alter signaling and survival

@nl

type

label

A secreted PTEN phosphatase that enters cells to alter signaling and survival

@ast

A secreted PTEN phosphatase that enters cells to alter signaling and survival

@en

A secreted PTEN phosphatase that enters cells to alter signaling and survival

@nl

prefLabel

A secreted PTEN phosphatase that enters cells to alter signaling and survival

@ast

A secreted PTEN phosphatase that enters cells to alter signaling and survival

@en

A secreted PTEN phosphatase that enters cells to alter signaling and survival

@nl

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P2860

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P356

SCIENCE.1234907

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P1476

A secreted PTEN phosphatase that enters cells to alter signaling and survival

@en

P2093

Barry Fine

http://www.w3.org/2001/XMLSchema#string

Benjamin Amendolara

http://www.w3.org/2001/XMLSchema#string

Benjamin D Hopkins

http://www.w3.org/2001/XMLSchema#string

Cindy Hodakoski

http://www.w3.org/2001/XMLSchema#string

Hanina Hibshoosh

http://www.w3.org/2001/XMLSchema#string

Hannah Goldstein

http://www.w3.org/2001/XMLSchema#string

Jacquelyn Shaw

http://www.w3.org/2001/XMLSchema#string

Jeffrey Bruce

http://www.w3.org/2001/XMLSchema#string

Jennifer S Yu

http://www.w3.org/2001/XMLSchema#string

Joshua Klein

http://www.w3.org/2001/XMLSchema#string

P2860

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

PTEN function: how normal cells control it and tumour cells lose it

Activation of the PI3K pathway in cancer through inhibition of PTEN by exchange factor P-REX2a

Brefeldin A: insights into the control of membrane traffic and organelle structure

The phosphoinositide 3-kinase pathway

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

Interfacial kinetic analysis of the tumour suppressor phosphatase, PTEN: evidence for activation by anionic phospholipids

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

Pten is essential for embryonic development and tumour suppression

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399-402

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scholarly article

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1368650

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10.1126/SCIENCE.1234907

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P407

P433

6144

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P478

341

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P577

2013-07-26T00:00:00Z

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23744781

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3935617

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