Cell type-specific protein-DNA interactions in the human zeta-globin upstream promoter region: displacement of Sp1 by the erythroid cell-specific factor NF-E1.
about
Developmental silencing of human zeta-globin gene expression is mediated by the transcriptional repressor RREB1A palindromic regulatory site within vertebrate GATA-1 promoters requires both zinc fingers of the GATA-1 DNA-binding domain for high-affinity interactionRescue of erythroid development in gene targeted GATA-1- mouse embryonic stem cellsRegulation of myelin basic protein gene transcription by Sp1 and Puralpha: evidence for association of Sp1 and Puralpha in brain.Annotation of cis-regulatory elements by identification, subclassification, and functional assessment of multispecies conserved sequencesTranscriptional activation of human adult alpha-globin genes by hypersensitive site-40 enhancer: function of nuclear factor-binding motifs occupied in erythroid cells.Proximal promoter elements of the human zeta-globin gene confer embryonic-specific expression on a linked reporter gene in transgenic miceStructure and function of the enhancer 3' to the human A gamma globin geneTranscriptional activation of human zeta 2 globin promoter by the alpha globin regulatory element (HS-40): functional role of specific nuclear factor-DNA complexes.Transcriptional role of a conserved GATA-1 site in the human epsilon-globin gene promoterRegulated expression of globin chains and the erythroid transcription factor GATA-1 during erythropoiesis in the developing mouse.Sp1 is a critical regulator of the Wilms' tumor-1 gene.Protein-DNA interactions in vivo of an erythroid-specific, human beta-globin locus enhancer.Mutually exclusive interactions between factors binding to adjacent Sp1 and AT-rich elements regulate gastrin gene transcription in insulinoma cells.CCACC-binding or simian-virus-40-protein-1-binding proteins cooperate with human GATA-1 to direct erythroid-specific transcription and to mediate 5' hypersensitive site 2 sensitivity of a TATA-less promoter.Distinct negative regulation of the human embryonic globin genes zeta and epsilon.Transcription factors Sp1 and Sp3 alter vascular endothelial growth factor receptor expression through a novel recognition sequence.Sp1 binds two sites in the CD11c promoter in vivo specifically in myeloid cells and cooperates with AP1 to activate transcriptionIn vitro and in vivo protein--DNA interactions on the rat erythroid-specific L' pyruvate kinase gene promoter.Characterization of the major regulatory element upstream of the human alpha-globin gene cluster.Nuclear factor 1 interferes with Sp1 binding through a composite element on the rat poly(ADP-ribose) polymerase promoter to modulate its activity in vitro.Sp3 mediates transcriptional activation of the leukocyte integrin genes CD11C and CD11B and cooperates with c-Jun to activate CD11C.In vitro analysis of the tissue plasminogen activator promoter reveals a GC box-binding activity present in murine brain but undetectable in kidney and liver.Developmental effect of the XmnI site on Ggamma-globin gene expression among newborn Hb F-Malta-I [Ggamma117(G19)His-->Arg, CAT-->CGT] heterozygotes and adult beta+ -Thalassemia homozygotes.
P2860
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P2860
Cell type-specific protein-DNA interactions in the human zeta-globin upstream promoter region: displacement of Sp1 by the erythroid cell-specific factor NF-E1.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Cell type-specific protein-DNA ...... id cell-specific factor NF-E1.
@ast
Cell type-specific protein-DNA ...... id cell-specific factor NF-E1.
@en
type
label
Cell type-specific protein-DNA ...... id cell-specific factor NF-E1.
@ast
Cell type-specific protein-DNA ...... id cell-specific factor NF-E1.
@en
prefLabel
Cell type-specific protein-DNA ...... id cell-specific factor NF-E1.
@ast
Cell type-specific protein-DNA ...... id cell-specific factor NF-E1.
@en
P2093
P2860
P356
P1476
Cell type-specific protein-DNA ...... id cell-specific factor NF-E1.
@en
P2093
P2860
P304
P356
10.1128/MCB.10.1.282
P407
P577
1990-01-01T00:00:00Z