Structural analysis of the mouse mdr1a (P-glycoprotein) promoter reveals the basis for differential transcript heterogeneity in multidrug-resistant J774.2 cells.
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Profile of Susan Band HorwitzAn analysis of vertebrate mRNA sequences: intimations of translational controlGenetic variation in the proximal promoter of ABC and SLC superfamilies: liver and kidney specific expression and promoter activity predict variationmRNA levels of related Abcb genes change opposite to each other upon histone deacetylase inhibition in drug-resistant rat hepatoma cellsFunctional analysis of chimeric genes obtained by exchanging homologous domains of the mouse mdr1 and mdr2 genesIdentification of trichlormethiazide as a Mdr1a/b gene expression enhancer via a dual secretion-based promoter assay.Regulation of P-glycoprotein gene expression in hepatocyte cultures and liver cell lines by a trans-acting transcriptional repressorModulation of p-glycoprotein transport function at the blood-brain barrier.Antimony-resistant but not antimony-sensitive Leishmania donovani up-regulates host IL-10 to overexpress multidrug-resistant protein 1.Regulation and expression of multidrug resistance (MDR) transcripts in the intestinal epithelium.Induction of liver alpha-1 acid glycoprotein gene expression involves both positive and negative transcription factorsCharacterization of the basal and carcinogen regulatory elements of the rat mdr1b promoter.Activation of the mouse mdr3 gene by insertion of retroviruses in multidrug-resistant P388 tumor cells.Bioimaging real-time PXR-dependent mdr1a gene regulation in mdr1a.fLUC reporter mice.A new model for studying tissue-specific mdr1a gene expression in vivo by live imagingClinico-pathologic function of cerebral ABC transporters - implications for the pathogenesis of Alzheimer's diseaseAlzheimer's disease and blood-brain barrier function-Why have anti-beta-amyloid therapies failed to prevent dementia progression?A single amino acid substitution strongly modulates the activity and substrate specificity of the mouse mdr1 and mdr3 drug efflux pumps.Transcriptional analysis of the EhPgp5 promoter of Entamoeba histolytica multidrug-resistant mutant.Transcriptional analysis of the EhPgp1 promoter of Entamoeba histolytica multidrug-resistant mutant.EhPgp5 mRNA stability is a regulatory event in the Entamoeba histolytica multidrug resistance phenotype.Cellular models for multiple drug resistance in cancer.Conditionally immortalized brain capillary endothelial cell lines established from a transgenic mouse harboring temperature-sensitive simian virus 40 large T-antigen gene.Xenobiotic transport differences in mouse mesangial cell clones expressing mdr1 and mdr3.Drug-induced changes in the expression of MDR-associated genes: investigations on cultured cell lines and chemotherapeutically treated leukemias.Two multidrug-resistant Friend leukemic cell lines selected with different drugs exhibit overproduction of different P-glycoproteins.P-glycoprotein and alterations in the glutathione/glutathione-peroxidase cycle underlie doxorubicin resistance in HL-60-R, a subclone of the HL-60 human leukemia cell line.Reduced mRNA levels for the multidrug-resistance genes in cAMP-dependent protein kinase mutant cell lines.Differential recognition of mdr1a and mdr1b gene products in multidrug resistant mouse tumour cell lines by different monoclonal antibodies.Co-amplification and over-expression of two mdr genes in a multidrug-resistant human colon carcinoma cell line.Induction of multidrug resistance gene expression during cholestasis in rats and nonhuman primates.Activation of distinct multidrug-resistance (P-glycoprotein) genes during rat liver regeneration and hepatocarcinogenesis.Regulation of 2-acetylaminofluorene-and 3-methylcholanthrene--mediated induction of multidrug resistance and cytochrome P450IA gene family expression in primary hepatocyte cultures and rat liver.Lack of modulation of MDR1 gene expression by dominant inhibition of cAMP-dependent protein kinase in doxorubicin-resistant MCF-7 breast cancer cells.Differential over-expression of mdr1 genes in multidrug-resistant rat glioblastoma cell lines selected with doxorubicin or vincristine.
P2860
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P2860
Structural analysis of the mouse mdr1a (P-glycoprotein) promoter reveals the basis for differential transcript heterogeneity in multidrug-resistant J774.2 cells.
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1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Structural analysis of the mou ...... tidrug-resistant J774.2 cells.
@ast
Structural analysis of the mou ...... tidrug-resistant J774.2 cells.
@en
type
label
Structural analysis of the mou ...... tidrug-resistant J774.2 cells.
@ast
Structural analysis of the mou ...... tidrug-resistant J774.2 cells.
@en
prefLabel
Structural analysis of the mou ...... tidrug-resistant J774.2 cells.
@ast
Structural analysis of the mou ...... tidrug-resistant J774.2 cells.
@en
P2093
P2860
P356
P1476
Structural analysis of the mou ...... tidrug-resistant J774.2 cells.
@en
P2093
L Lothstein
L S Kirschner
M Hartstein
S B Horwitz
P2860
P304
P356
10.1128/MCB.10.7.3596
P407
P577
1990-07-01T00:00:00Z