Myeloid-derived suppressor cells regulate growth of multiple myeloma by inhibiting T cells in bone marrow. - Wikidata - wikimedia - TriplyDB

Myeloid-derived suppressor cells regulate growth of multiple myeloma by inhibiting T cells in bone marrow.

Myeloid-derived suppressor cells regulate growth of multiple myeloma by inhibiting T cells in bone marrow.

http://www.wikidata.org/entity/Q36718300

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Bone Marrow Immunity and Myelodysplasia The Tumor Macroenvironment: Cancer-Promoting Networks Beyond Tumor Beds HDAC inhibitors and immunotherapy; a double edged sword?Myeloid-derived suppressor cells as therapeutic target in hematological malignancies The tumor microenvironment shapes hallmarks of mature B-cell malignancies.Novel therapeutic strategies for multiple myeloma Myeloid-derived suppressor cells in the development of lung cancer.Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patients.Targeting innate immunity to downmodulate adaptive immunity and reverse type 1 diabetes.Superior GVHD-free, relapse-free survival for G-BM to G-PBSC grafts is associated with higher MDSCs content in allografting for patients with acute leukemia.Chronic intake of high fish oil diet induces myeloid-derived suppressor cells to promote tumor growth.Complexity and challenges in defining myeloid-derived suppressor cells Bone-immune cell crosstalk: bone diseases.Myeloid derived suppressor cells in chronic myeloid leukemia.Survivin-specific CD4+ T cells are decreased in patients with survivin-positive myeloma.Ex Vivo Maintenance of Primary Human Multiple Myeloma Cells through the Optimization of the Osteoblastic Niche.Multiple myeloma induces Mcl-1 expression and survival of myeloid-derived suppressor cells.Dynamic interplay between bone and multiple myeloma: emerging roles of the osteoblast Inflammatory and oncogenic roles of a tumor stem cell marker doublecortin-like kinase (DCLK1) in virus-induced chronic liver diseases Neutrophil to lymphocyte ratio (NLR) improves the risk assessment of ISS staging in newly diagnosed MM patients treated upfront with novel agents.Dissecting the multiple myeloma-bone microenvironment reveals new therapeutic opportunities The bone marrow microenvironment enhances multiple myeloma progression by exosome-mediated activation of myeloid-derived suppressor cells.Deregulation of apoptotic factors Bcl-xL and Bax confers apoptotic resistance to myeloid-derived suppressor cells and contributes to their persistence in cancer.Bone marrow PMN-MDSCs and neutrophils are functionally similar in protection of multiple myeloma from chemotherapy Identification of granulocytic myeloid-derived suppressor cells (G-MDSCs) in the peripheral blood of Hodgkin and non-Hodgkin lymphoma patients.Granulocytic myeloid-derived suppressor cells promote angiogenesis in the context of multiple myeloma.Myeloid-derived suppressor cells are associated with viral persistence and downregulation of TCR ζ chain expression on CD8(+) T cells in chronic hepatitis C patients.Immunotherapeutic approaches to treat multiple myeloma Future agents and treatment directions in multiple myeloma.Myeloid-derived suppressor cell heterogeneity in human cancers.Immunological dysregulation in multiple myeloma microenvironment.Myeloid-derived suppressor cells: their role in the pathophysiology of hematologic malignancies and potential as therapeutic targets.Targeting the bone marrow microenvironment in multiple myeloma.Myeloid-derived suppressor cells in multiple myeloma: pre-clinical research and translational opportunities.Beyond consolidation: auto-SCT and immunotherapy for plasma cell myeloma.Myeloid-derived suppressor cells in B cell malignancies.Adoptive Cell Therapy in Multiple Myeloma.Immune responses in multiple myeloma: role of the natural immune surveillance and potential of immunotherapies.Multiple myeloma exosomes establish a favourable bone marrow microenvironment with enhanced angiogenesis and immunosuppression.Role of the Immune Response in Disease Progression and Therapy in Multiple Myeloma.

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Myeloid-derived suppressor cells regulate growth of multiple myeloma by inhibiting T cells in bone marrow.

http://www.wikidata.org/entity/Q36718300

description

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Myeloid-derived suppressor cel ...... biting T cells in bone marrow.

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Myeloid-derived suppressor cel ...... biting T cells in bone marrow.

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Myeloid-derived suppressor cel ...... biting T cells in bone marrow.

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Journal of Immunology

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Myeloid-derived suppressor cel ...... ibiting T cells in bone marrow

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Alexandra Pisklakova

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Dmitry Gabrilovich

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Indu R Ramachandran

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Johannes Roth

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Tess Chase

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Thomas Condamine

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Thomas Vogl

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Yulia Nefedova

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P2860

Loss of S100A9 (MRP14) results in reduced interleukin-8-induced CD11b surface expression, a polarized microfilament system, and diminished responsiveness to chemoattractants in vitro

Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells

Myeloid-derived suppressor cells as regulators of the immune system

Coordinated regulation of myeloid cells by tumours

Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function

Subsets of myeloid-derived suppressor cells in tumor-bearing mice

Anti-inflammatory triterpenoid blocks immune suppressive function of MDSCs and improves immune response in cancer.

Antigen-specific CD4(+) T cells regulate function of myeloid-derived suppressor cells in cancer via retrograde MHC class II signaling.

Advances in the understanding of myeloma bone disease and tumour growth.

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