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On the replication of genetic associations: timing can be everything!

On the replication of genetic associations: timing can be everything!

http://www.wikidata.org/entity/Q36719042

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The influence of serotonin- and other genes on impulsive behavioral aggression and cognitive impulsivity in children with attention-deficit/hyperactivity disorder (ADHD): Findings from a family-based association test (FBAT) analysis Common genetic determinants of vitamin D insufficiency: a genome-wide association study Analyses of shared genetic factors between asthma and obesity in children No evidence of association of heterozygous NTF4 mutations in patients with primary open-angle glaucoma Genome-wide association analysis of metabolic traits in a birth cohort from a founder population Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia Confluence of genes, environment, development, and behavior in a post Genome-Wide Association Study world Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups HLA-DQ strikes again: genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults.Etiology of Obesity Over the Life Span: Ecological and Genetic Highlights from Asian Countries.Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes.Visualizing disease associations: graphic analysis of frequency distributions as a function of age using moving average plots (MAP) with application to Alzheimer's and Parkinson's disease Estimating peer effects in longitudinal dyadic data using instrumental variables.Emilin1 gene and essential hypertension: a two-stage association study in northern Han Chinese population.Screening and replication using the same data set: testing strategies for family-based studies in which all probands are affected Failure to replicate a genetic association may provide important clues about genetic architecture A data-driven weighting scheme for family-based genome-wide association studies.Application of three-level linear mixed-effects model incorporating gene-age interactions for association analysis of longitudinal family data Life course variations in the associations between FTO and MC4R gene variants and body size Statistical challenges for genome-wide association studies of suicidality using family data.Mutation screen and association studies for the fatty acid amide hydrolase (FAAH) gene and early onset and adult obesity.A large replication study and meta-analysis in European samples provides further support for association of AHI1 markers with schizophrenia.On genome-wide association studies for family-based designs: an integrative analysis approach combining ascertained family samples with unselected controls.Genetic and genomic analysis of hyperlipidemia, obesity and diabetes using (C57BL/6J × TALLYHO/JngJ) F2 mice.Association of ADIPOQ gene variants with body weight, type 2 diabetes and serum adiponectin concentrations: the Finnish Diabetes Prevention Study.Recent human evolution has shaped geographical differences in susceptibility to disease Flexible estimation of covariance function by penalized spline with application to longitudinal family data.An NFKB1 promoter insertion/deletion polymorphism influences risk and outcome in acute respiratory distress syndrome among Caucasians Aging-related atherosclerosis is exacerbated by arterial expression of tumor necrosis factor receptor-1: evidence from mouse models and human association studies.Study of eight GWAS-identified common variants for association with obesity-related indices in Chinese children at puberty.Bivariate association analysis of longitudinal phenotypes in families.Life-course analysis of a fat mass and obesity-associated (FTO) gene variant and body mass index in the Northern Finland Birth Cohort 1966 using structural equation modeling.Controversial association results for INSIG2 on body mass index may be explained by interactions with age and with MC4R Genomic convergence of genome-wide investigations for complex traits Genetic contributions to clinical pain and analgesia: avoiding pitfalls in genetic research Associations between variation in CHRNA5-CHRNA3-CHRNB4, body mass index and blood pressure in the Northern Finland Birth Cohort 1966 Individualized pain medicine ARG1 is a novel bronchodilator response gene: screening and replication in four asthma cohorts In search of the perfect phenotype: an analysis of linkage and association studies of reading and reading-related processes.Cohort of birth modifies the association between FTO genotype and BMI.

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On the replication of genetic associations: timing can be everything!

http://www.wikidata.org/entity/Q36719042

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2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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On the replication of genetic associations: timing can be everything!

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On the replication of genetic associations: timing can be everything!

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On the replication of genetic associations: timing can be everything!

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On the replication of genetic associations: timing can be everything!

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On the replication of genetic associations: timing can be everything!

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J.AJHG.2008.01.018

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American Journal of Human Genetics

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On the replication of genetic associations: timing can be everything!

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Barbara Klanderman

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Benjamin A Raby

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Caren Vollmert

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Caroline S Fox

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Christoph Lange

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Christopher J O'Donnell

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Cliona Molony

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Constantina Papoutsakis

http://www.w3.org/2001/XMLSchema#string

Daniel Levy

http://www.w3.org/2001/XMLSchema#string

Edwin K Silverman

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P2860

The axon guidance receptor gene ROBO1 is a candidate gene for developmental dyslexia

The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts

Lack of support for the association between GAD2 polymorphisms and severe human obesity.

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

A common inversion under selection in Europeans

Replication validity of genetic association studies

High-throughput development and characterization of a genomewide collection of gene-based single nucleotide polymorphism markers by chip-based matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

Pooling analysis of genetic data: the association of leptin receptor (LEPR) polymorphisms with variables related to human adiposity

The Framingham Offspring Study. Design and preliminary data.

Genomic screening and replication using the same data set in family-based association testing.

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849-858

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scholarly article

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10.1016/J.AJHG.2008.01.018

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4

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82

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Gudmar Thorleifsson

Unnur Þorsteinsdóttir

Kári Stefánsson

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2008-04-01T00:00:00Z

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5464142

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18387595

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2427263

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