Human cytochrome P450 3A4: enzymatic properties of a purified recombinant fusion protein containing NADPH-P450 reductase.
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Diversification of catalytic function in a synthetic family of chimeric cytochrome p450sCharacterization of Saccharomyces cerevisiae CYP51 and a CYP51 fusion protein with NADPH cytochrome P-450 oxidoreductase expressed in Escherichia coli.Variations on a (t)heme--novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamilyCo-administration of GF120918 significantly increases the systemic exposure to oral paclitaxel in cancer patientsMetabolism of N,N-dialkylated amphetamines, including deprenyl, by CYP2D6 expressed in a human cell lineA novel sterol 14alpha-demethylase/ferredoxin fusion protein (MCCYP51FX) from Methylococcus capsulatus represents a new class of the cytochrome P450 superfamily.Cytochrome P450-based cancer gene therapy: recent advances and future prospects.Electrocatalytically driven omega-hydroxylation of fatty acids using cytochrome P450 4A1Enhanced oral bioavailability of paclitaxel in mice treated with the P-glycoprotein blocker SDZ PSC 833.Nanoscale electron transport measurements of immobilized cytochrome P450 proteins.Catalytic, mild, and selective oxyfunctionalization of linear alkanes: current challenges.Chimeric P450 enzymes: activity of artificial redox fusions driven by different reductases for biotechnological applications.A virus-directed enzyme prodrug therapy (VDEPT) strategy for lung cancer using a CYP2B6/NADPH-cytochrome P450 reductase fusion protein.In vitro assessment of human cytochrome P450.New applications of bacterial systems to problems in toxicology.CO binding kinetics of human cytochrome P450 3A4. Specific interaction of substrates with kinetically distinguishable conformers.Fused p47phox and p67phox truncations efficiently reconstitute NADPH oxidase with higher activity and stability than the individual components.Stimulation of cytochrome P450 reactions by apo-cytochrome b5: evidence against transfer of heme from cytochrome P450 3A4 to apo-cytochrome b5 or heme oxygenase.Cooperativity of alpha-naphthoflavone in cytochrome P450 3A-dependent drug oxidation activities in hepatic and intestinal microsomes from mouse and human.Optimizing bacterial expression of catalytically active human cytochromes P450: comparison of CYP2C8 and CYP2C9.Putidaredoxin reductase-putidaredoxin-cytochrome p450cam triple fusion protein. Construction of a self-sufficient Escherichia coli catalytic system.Analysis of the interactions of cytochrome b5 with flavocytochrome P450 BM3 and its domains.Use of genetically engineered Salmonella typhimurium OY1002/1A2 strain coexpressing human cytochrome P450 1A2 and NADPH-cytochrome P450 reductase and bacterial O-acetyltransferase in SOS/umu assay.The use of electrochemistry for the synthesis of 17 alpha-hydroxyprogesterone by a fusion protein containing P450c17.Lack of electron transfer from cytochrome b5 in stimulation of catalytic activities of cytochrome P450 3A4. Characterization of a reconstituted cytochrome P450 3A4/NADPH-cytochrome P450 reductase system and studies with apo-cytochrome b5.
P2860
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P2860
Human cytochrome P450 3A4: enzymatic properties of a purified recombinant fusion protein containing NADPH-P450 reductase.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Human cytochrome P450 3A4: enz ...... ntaining NADPH-P450 reductase.
@ast
Human cytochrome P450 3A4: enz ...... ntaining NADPH-P450 reductase.
@en
type
label
Human cytochrome P450 3A4: enz ...... ntaining NADPH-P450 reductase.
@ast
Human cytochrome P450 3A4: enz ...... ntaining NADPH-P450 reductase.
@en
prefLabel
Human cytochrome P450 3A4: enz ...... ntaining NADPH-P450 reductase.
@ast
Human cytochrome P450 3A4: enz ...... ntaining NADPH-P450 reductase.
@en
P2093
P2860
P356
P1476
Human cytochrome P450 3A4: enz ...... ntaining NADPH-P450 reductase.
@en
P2093
C W Fisher
P L Holmans
R W Estabrook
P2860
P304
11748-11752
P356
10.1073/PNAS.90.24.11748
P407
P577
1993-12-01T00:00:00Z