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Cooperativity in monomeric enzymes with single ligand-binding sitesMetabolism of BYZX in human liver microsomes and cytosol: identification of the metabolites and metabolic pathways of BYZXEvaluation of 7-benzyloxy-4-trifluoromethylcoumarin, some other 7-hydroxy-4-trifluoromethylcoumarin derivatives and 7-benzyloxyquinoline as fluorescent substrates for rat hepatic cytochrome P450 enzymesUse of in vitro drug metabolism data to evaluate metabolic drug-drug interactions in man: the need for quantitative databases.Summary of information on human CYP enzymes: human P450 metabolism data.New cathinone-derived designer drugs 3-bromomethcathinone and 3-fluoromethcathinone: studies on their metabolism in rat urine and human liver microsomes using GC-MS and LC-high-resolution MS and their detectability in urine.Allosteric phenomena in cytochrome P450-catalyzed monooxygenations.The in vivo and in vitro metabolism and the detectability in urine of 3',4'-methylenedioxy-alpha-pyrrolidinobutyrophenone (MDPBP), a new pyrrolidinophenone-type designer drug, studied by GC-MS and LC-MS(n.).Assessment of drug-drug interactions: concepts and approaches.Human drug metabolism and the cytochromes P450: application and relevance of in vitro models.Identification of cytochrome P450 enzymes involved in the metabolism of 3',4'-methylenedioxy-alpha-pyrrolidinopropiophenone (MDPPP), a designer drug, in human liver microsomes.Interactions of herbs with cytochrome P450.Discovery of a highly selective CYP3A4 inhibitor suitable for reaction phenotyping studies and differentiation of CYP3A4 and CYP3A5.Tyrosine kinase inhibitors and drug interactions: a review with practical recommendations.A High-Throughput (HTS) Assay for Enzyme Reaction Phenotyping in Human Recombinant P450 Enzymes Using LC-MS/MS.Relative contributions of the major human CYP450 to the metabolism of icotinib and its implication in prediction of drug-drug interaction between icotinib and CYP3A4 inhibitors/inducers using physiologically based pharmacokinetic modeling.Cytochrome P450 mono-oxygenase gene expression and protein activity in cultures of adult cardiomyocytes of the rat.Metabolism of styrene in the human liver in vitro: interindividual variation and enantioselectivity.Kinetics of metabolism and degradation of mometasone furoate in rat biological fluids and tissues.In vivo metabolism of the new designer drug 1-(4-methoxyphenyl)piperazine (MeOPP) in rat and identification of the human cytochrome P450 enzymes responsible for the major metabolic step.
P2860
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P2860
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
In vitro assessment of human cytochrome P450.
@en
type
label
In vitro assessment of human cytochrome P450.
@en
prefLabel
In vitro assessment of human cytochrome P450.
@en
P2860
P356
P1433
P1476
In vitro assessment of human cytochrome P450.
@en
P2093
P2860
P304
P356
10.1080/004982598238877
P407
P577
1998-12-01T00:00:00Z