Structure and expression of the mouse beta-hexosaminidase genes, Hexa and Hexb.
about
Firing up the nature/nurture controversy: bioethics and genetic determinismImpaired neural differentiation of induced pluripotent stem cells generated from a mouse model of Sandhoff diseaseIdentification of domains in human beta-hexosaminidase that determine substrate specificityTargeted disruption of the Hexa gene results in mice with biochemical and pathologic features of Tay-Sachs diseaseMouse models of Tay-Sachs and Sandhoff diseases differ in neurologic phenotype and ganglioside metabolismSpecificity of mouse GM2 activator protein and beta-N-acetylhexosaminidases A and B. Similarities and differences with their human counterparts in the catabolism of GM2FcRγ-dependent immune activation initiates astrogliosis during the asymptomatic phase of Sandhoff disease model miceHexosaminidase-altered aberrant crypts, carrying decreased hexosaminidase alpha and beta subunit mRNAs, in colon of 1,2-dimethylhydrazine-treated rats.Early changes in the apparent diffusion coefficient (ADC) in a mouse model of Sandhoff's disease occur prior to disease symptoms and behavioral deficitsThymic alterations in GM2 gangliosidoses model mice.Possible role of autoantibodies in the pathophysiology of GM2 gangliosidoses.Novel Mutations in Sandhoff Disease: A Molecular Analysis among Iranian Cohort of Infantile PatientsTSPO in a murine model of Sandhoff disease: presymptomatic marker of neurodegeneration and disease pathophysiology.Glycosphingolipid storage leads to the enhanced degradation of the B cell receptor in Sandhoff disease mice.Metabolic correction in microglia derived from Sandhoff disease model mice.Molecular cloning and functional characterization of beta-N-acetylglucosaminidase genes from Sf9 cells.Neuroinflammation as modifier of genetically caused neurological disorders of the central nervous system: Understanding pathogenesis and chances for treatment.Expression of human beta-hexosaminidase alpha-subunit gene (the gene defect of Tay-Sachs disease) in mouse brains upon engraftment of transduced progenitor cells.Clinical, enzymatic, and molecular characterisation of a Portuguese family with a chronic form of GM2-gangliosidosis B1 variant.Structural organization and expression of the gene for the mouse GM2 activator protein.Molecular and functional analysis of the HEXB gene in Italian patients affected with Sandhoff disease: identification of six novel alleles.Expression and regulation of the human and mouse aspartylglucosaminidase gene.Lysosomal storage results in impaired survival but normal neurite outgrowth in dorsal root ganglion neurones from a mouse model of Sandhoff disease.
P2860
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P2860
Structure and expression of the mouse beta-hexosaminidase genes, Hexa and Hexb.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Structure and expression of the mouse beta-hexosaminidase genes, Hexa and Hexb.
@ast
Structure and expression of the mouse beta-hexosaminidase genes, Hexa and Hexb.
@en
type
label
Structure and expression of the mouse beta-hexosaminidase genes, Hexa and Hexb.
@ast
Structure and expression of the mouse beta-hexosaminidase genes, Hexa and Hexb.
@en
prefLabel
Structure and expression of the mouse beta-hexosaminidase genes, Hexa and Hexb.
@ast
Structure and expression of the mouse beta-hexosaminidase genes, Hexa and Hexb.
@en
P2093
P356
P1433
P1476
Structure and expression of the mouse beta-hexosaminidase genes, Hexa and Hexb
@en
P2093
P304
P356
10.1006/GENO.1994.1318
P577
1994-06-01T00:00:00Z