PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation
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A2B adenosine receptor gene deletion attenuates murine colitis.Butyrate transcriptionally enhances peptide transporter PepT1 expression and activity.Molecular cloning and functional expression of atlantic salmon peptide transporter 1 in Xenopus oocytes reveals efficient intestinal uptake of lysine-containing and other bioactive di- and tripeptides in teleost fish.Gene ablation for PEPT1 in mice abolishes the effects of dipeptides on small intestinal fluid absorption, short-circuit current, and intracellular pH.PepT1 mediates transport of the proinflammatory bacterial tripeptide L-Ala-{gamma}-D-Glu-meso-DAP in intestinal epithelial cells.Cytokine regulation of OCTN2 expression and activity in small and large intestineMicroRNA-92b regulates expression of the oligopeptide transporter PepT1 in intestinal epithelial cells.Single administration of tripeptide α-MSH(11-13) attenuates brain damage by reduced inflammation and apoptosis after experimental traumatic brain injury in mice.Colonic miRNA expression/secretion, regulated by intestinal epithelial PepT1, plays an important role in cell-to-cell communication during colitis.The tripeptide KdPT protects from intestinal inflammation and maintains intestinal barrier function.The PepT1-NOD2 signaling pathway aggravates induced colitis in miceNotch1 regulates the effects of matrix metalloproteinase-9 on colitis-associated cancer in mice.MicroRNA-193a-3p Reduces Intestinal Inflammation in Response to Microbiota via Down-regulation of Colonic PepT1The role and pathophysiological relevance of membrane transporter PepT1 in intestinal inflammation and inflammatory bowel disease.Inhibition of cellular and systemic inflammation cues in human bronchial epithelial cells by melanocortin-related peptides: mechanism of KPV action and a role for MC3R agonistsA(₂B)AR expression in non-immune cells plays an important role in the development of murine colitisAlpha-Melanocyte Stimulating Hormone Protects against Cytokine-Induced Barrier Damage in Caco-2 Intestinal Epithelial MonolayersPepT1 Expression Helps Maintain Intestinal Homeostasis by Mediating the Differential Expression of miRNAs along the Crypt-Villus AxisCritical role of PepT1 in promoting colitis-associated cancer and therapeutic benefits of the anti-inflammatory PepT1-mediated tripeptide KPV in a murine model.Pathogenic bacteria induce colonic PepT1 expression: an implication in host defense response.Targeted disruption of peptide transporter Pept1 gene in mice significantly reduces dipeptide absorption in intestineBeneficial effect of probiotics in IBD: are peptidogycan and NOD2 the molecular key effectors?New targeting strategies in drug therapy of inflammatory bowel disease: mechanistic approaches and opportunities.Teleost fish models in membrane transport research: the PEPT1(SLC15A1) H+-oligopeptide transporter as a case study.Hair curvature: a natural dialectic and review.Intestinal barrier dysfunction: implications for chronic inflammatory conditions of the bowel.Di- and tripeptide transport in vertebrates: the contribution of teleost fish models.Evidence for two different broad-specificity oligopeptide transporters in intestinal cell line Caco-2 and colonic cell line CCD841.The tripeptide KdPT ameliorates ongoing psoriasis-like skin inflammation in murine and human skin.A quantitative structure-activity relationship for translocation of tripeptides via the human proton-coupled peptide transporter, hPEPT1 (SLC15A1)Clinical relevance of intestinal peptide uptake.Constitutive expression of MMP9 in intestinal epithelium worsens murine acute colitis and is associated with increased levels of proinflammatory cytokine Kc.Lactobacillus plantarum ameliorates colonic epithelial barrier dysfunction by modulating the apical junctional complex and PepT1 in IL-10 knockout mice.Expression and regulation of proton-coupled oligopeptide transporters in colonic tissue and immune cells of mice.PepT1 oligopeptide transporter (SLC15A1) gene polymorphism in inflammatory bowel disease.Morphological adaptation with preserved proliferation/transporter content in the colon of patients with short bowel syndrome.Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis.An engineered cyclic peptide alleviates symptoms of inflammation in a murine model of inflammatory bowel disease.
P2860
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P2860
PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation
@ast
PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation
@en
type
label
PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation
@ast
PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation
@en
prefLabel
PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation
@ast
PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation
@en
P2093
P2860
P1433
P1476
PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation
@en
P2093
Didier Merlin
Hang Thi Thu Nguyen
Laetitia Charrier-Hisamuddin
Shanthi Sitaraman
P2860
P304
P356
10.1053/J.GASTRO.2007.10.026
P407
P577
2007-10-17T00:00:00Z