about
Single-molecule dynamics and mechanisms of metalloregulators and metallochaperonesIron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseasesCopper-triggered aggregation of ubiquitin.A series of tripodal cysteine derivatives as water-soluble chelators that are highly selective for copper(I).Fluorescent sensors for measuring metal ions in living systemsCarbonic anhydrase I, II, and VI, blood plasma, erythrocyte and saliva zinc and copper increase after repetitive transcranial magnetic stimulation.Divalent cation tolerance protein binds to β-secretase and inhibits the processing of amyloid precursor protein.Mouse Models of Oxidative Stress Indicate a Role for Modulating Healthy Aging.Tackling metal regulation and transport at the single-molecule level.Relating dynamic protein interactions of metallochaperones with metal transfer at the single-molecule levelFluorescence lifetime imaging of physiological free Cu(II) levels in live cells with a Cu(II)-selective carbonic anhydrase-based biosensor.Cellular sensing and transport of metal ions: implications in micronutrient homeostasis.Copper-64 Radiopharmaceuticals for Oncologic ImagingCopper(II) binding to alpha-synuclein, the Parkinson's protein.The role of antioxidant supplement in immune system, neoplastic, and neurodegenerative disorders: a point of view for an assessment of the risk/benefit profileRole of copper and cholesterol association in the neurodegenerative process.Bioinorganic chemistry of copper and zinc ions coordinated to amyloid-beta peptide.Short peptides self-assemble to produce catalytic amyloids.Oxidative stress and cell membranes in the pathogenesis of Alzheimer's disease.Interactions of Zn(II) and Cu(II) ions with Alzheimer's amyloid-beta peptide. Metal ion binding, contribution to fibrillization and toxicity.Developing luminescent silver nanodots for biological applications.Metallostasis and amyloid β-degrading enzymes.Tools to study distinct metal pools in biology.Analytical methods for copper, zinc and iron quantification in mammalian cells.A review of metal-catalyzed molecular damage: protection by melatonin.Fluorescent silver nanoclusters stabilized by DNA scaffolds.Supplementation with zinc in rats enhances memory and reverses an age-dependent increase in plasma copper.The structural flexibility of the human copper chaperone Atox1: Insights from combined pulsed EPR studies and computations.Role of the cellular prion protein in the neuron adaptation strategy to copper deficiency.Pregabalin antagonizes copper-induced toxicity in the brain: in vitro and in vivo studies.Copper(II) complexes of hybrid hydroxyquinoline-thiosemicarbazone ligands: GSK3β inhibition due to intracellular delivery of copper.A set of robust fluorescent peptide probes for quantification of Cu(ii) binding affinities in the micromolar to femtomolar range.Trehalose Improves Cognition in the Transgenic Tg2576 Mouse Model of Alzheimer's Disease.Structural studies of copper(I) complexes of amyloid-beta peptide fragments: formation of two-coordinate bis(histidine) complexes.The Effects of Copper on Brain Microvascular Endothelial Cells and Claudin Via Apoptosis and Oxidative Stress.Evaluation of quantitative probes for weaker Cu(i) binding sites completes a set of four capable of detecting Cu(i) affinities from nanomolar to attomolar.Application of the comprehensive set of heterozygous yeast deletion mutants to elucidate the molecular basis of cellular chromium toxicity.Probing transient copper chaperone-Wilson disease protein interactions at the single-molecule level with nanovesicle trapping.Neuroprotective Role of a Novel Copper Chelator against Aβ 42 Induced Neurotoxicity.Mutual interference of Cu and Zn ions in Alzheimer's disease: perspectives at the molecular level.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Copper and Alzheimer's disease.
@ast
Copper and Alzheimer's disease.
@en
type
label
Copper and Alzheimer's disease.
@ast
Copper and Alzheimer's disease.
@en
prefLabel
Copper and Alzheimer's disease.
@ast
Copper and Alzheimer's disease.
@en
P1476
Copper and Alzheimer's disease
@en
P2093
Anthony G Wedd
Paul S Donnelly
P304
P356
10.1016/J.CBPA.2007.01.678
P577
2007-02-14T00:00:00Z