Progestins both stimulate and inhibit breast cancer cell cycle progression while increasing expression of transforming growth factor alpha, epidermal growth factor receptor, c-fos, and c-myc genes
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Epidermal growth factor suppresses induction by progestin of the adhesion protein desmoplakin in T47D breast cancer cellsDownregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer developmentCUE domain containing 2 regulates degradation of progesterone receptor by ubiquitin-proteasomeHDLG5/KIAA0583, encoding a MAGUK-family protein, is a primary progesterone target gene in breast cancer cellsHormonal Modulation of Breast Cancer Gene Expression: Implications for Intrinsic Subtyping in Premenopausal WomenDeciphering the divergent roles of progestogens in breast cancer.Integrity of the LXXLL motif in Stat6 is required for the inhibition of breast cancer cell growth and enhancement of differentiation in the context of progesterone.Linkage of progestin and epidermal growth factor signaling: phosphorylation of progesterone receptors mediates transcriptional hypersensitivity and increased ligand-independent breast cancer cell growth.Progesterone receptor rapid signaling mediates serine 345 phosphorylation and tethering to specificity protein 1 transcription factors.The antiproliferative effects of progestins in T47D breast cancer cells are tempered by progestin induction of the ETS transcription factor Elf5.Progesterone and breast cancer.The progesterone receptor hinge region regulates the kinetics of transcriptional responses through acetylation, phosphorylation, and nuclear retention.Human progesterone receptor displays cell cycle-dependent changes in transcriptional activity.Cooperation of p27(Kip1) and p18(INK4c) in progestin-mediated cell cycle arrest in T-47D breast cancer cells.Growth factor and sex steroid interactions in breast cancer.Transcriptional hyperactivity of human progesterone receptors is coupled to their ligand-dependent down-regulation by mitogen-activated protein kinase-dependent phosphorylation of serine 294.Mechanisms of cyclin-dependent kinase inactivation by progestinsProgestin upregulates G-protein-coupled receptor 30 in breast cancer cells.Progesterone receptors, their isoforms and progesterone regulated transcriptionProgestins and progesterone in hormone replacement therapy and the risk of breast cancer.Novel progesterone target genes identified by an improved differential display technique suggest that progestin-induced growth inhibition of breast cancer cells coincides with enhancement of differentiation.Differential regulation of breast cancer-associated genes by progesterone receptor isoforms PRA and PRB in a new bi-inducible breast cancer cell line.New progestagens for contraceptive use.Regulation of progesterone receptor signaling by BRCA1 in mammary cancer.WISP-2 gene in human breast cancer: estrogen and progesterone inducible expression and regulation of tumor cell proliferation.Divergent behavior of cyclin E and its low molecular weight isoforms to progesterone-induced growth inhibition in MCF-7 cells.ck2-dependent phosphorylation of progesterone receptors (PR) on Ser81 regulates PR-B isoform-specific target gene expression in breast cancer cells.Progesterone action in breast, uterine, and ovarian cancers.Progestin and antiprogestin responsiveness in breast cancer is driven by the PRA/PRB ratio via AIB1 or SMRT recruitment to the CCND1 and MYC promoters.Progesterone receptors upregulate Wnt-1 to induce epidermal growth factor receptor transactivation and c-Src-dependent sustained activation of Erk1/2 mitogen-activated protein kinase in breast cancer cells.Cyclin D1 induction in breast cancer cells shortens G1 and is sufficient for cells arrested in G1 to complete the cell cycle.Identification of therapeutic targets for breast cancer using biological informatics methods.Progesterone regulation of stem and progenitor cells in normal and malignant breastHuman breast cell proliferation and its relationship to steroid receptor expression.Progesterone receptor blockade in human breast cancer cells decreases cell cycle progression through G2/M by repressing G2/M genes.Progestin modulates the lipid profile and sensitivity of breast cancer cells to docetaxelIncreased levels of the cell cycle inhibitor protein, dacapo, accompany 20-hydroxyecdysone-induced G1 arrest in a mosquito cell line.Progesterone-inducible cytokeratin 5-positive cells in luminal breast cancer exhibit progenitor properties.Growth factor, steroid, and steroid antagonist regulation of cyclin gene expression associated with changes in T-47D human breast cancer cell cycle progression.Challenges to defining a role for progesterone in breast cancer.
P2860
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P2860
Progestins both stimulate and inhibit breast cancer cell cycle progression while increasing expression of transforming growth factor alpha, epidermal growth factor receptor, c-fos, and c-myc genes
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Progestins both stimulate and ...... ceptor, c-fos, and c-myc genes
@ast
Progestins both stimulate and ...... ceptor, c-fos, and c-myc genes
@en
type
label
Progestins both stimulate and ...... ceptor, c-fos, and c-myc genes
@ast
Progestins both stimulate and ...... ceptor, c-fos, and c-myc genes
@en
prefLabel
Progestins both stimulate and ...... ceptor, c-fos, and c-myc genes
@ast
Progestins both stimulate and ...... ceptor, c-fos, and c-myc genes
@en
P2093
P2860
P356
P1476
Progestins both stimulate and ...... ceptor, c-fos, and c-myc genes
@en
P2093
Musgrove EA
Sutherland RL
P2860
P304
P356
10.1128/MCB.11.10.5032
P407
P577
1991-10-01T00:00:00Z