In vivo osteoarthritis target validation utilizing genetically-modified mice.
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Cellular ageing mechanisms in osteoarthritisGenetically Engineered Mouse Models Reveal the Importance of Proteases as Osteoarthritis Drug TargetsOsteoimmunology and the influence of pro-inflammatory cytokines on osteoclastsAnimal Models of Osteoarthritis: Comparisons and Key ConsiderationsPost-traumatic arthritis: overview on pathogenic mechanisms and role of inflammationNonproliferative and Proliferative Lesions of the Rat and Mouse Skeletal Tissues (Bones, Joints, and Teeth)Revisiting the Role of Interleukin-1 Pathway in Osteoarthritis: Interleukin-1α and -1β, and NLRP3 Inflammasome Are Not Involved in the Pathological Features of the Murine Menisectomy Model of Osteoarthritis.Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis.Comprehensive profiling of cartilage extracellular matrix formation and maturation using sequential extraction and label-free quantitative proteomics.Establishment of a surgically-induced model in mice to investigate the protective role of progranulin in osteoarthritis.Biological aspects of early osteoarthritis.Identification of a central role for complement in osteoarthritis.Mangiferin reduces the inhibition of chondrogenic differentiation by IL-1β in mesenchymal stem cells from subchondral bone and targets multiple aspects of the Smad and SOX9 pathwaysADAMTS-7 forms a positive feedback loop with TNF-α in the pathogenesis of osteoarthritis.Biomechanical influence of cartilage homeostasis in health and diseaseGenetic evidence of the regulatory role of parathyroid hormone-related protein in articular chondrocyte maintenance in an experimental mouse model.Proteases involved in cartilage matrix degradation in osteoarthritis.Translational development of an ADAMTS-5 antibody for osteoarthritis disease modification.Cartilage and bone changes during development of post-traumatic osteoarthritis in selected LGXSM recombinant inbred miceChondrogenesis, chondrocyte differentiation, and articular cartilage metabolism in health and osteoarthritis.Preparation of Low Molecular Weight Chondroitin Sulfates, Screening of a High Anti-Complement Capacity of Low Molecular Weight Chondroitin Sulfate and Its Biological Activity Studies in Attenuating Osteoarthritis.Generation and characterization of ABT-981, a dual variable domain immunoglobulin (DVD-Ig(TM)) molecule that specifically and potently neutralizes both IL-1α and IL-1β.Inflammation in joint injury and post-traumatic osteoarthritisDo mouse models reflect the diversity of osteoarthritis in humans?CCL2 and CCR2 regulate pain-related behaviour and early gene expression in post-traumatic murine osteoarthritis but contribute little to chondropathy.Chondrocyte apoptosis: a cause or consequence of osteoarthritis?Etiology of osteoarthritis: genetics and synovial joint development.Using mouse models to investigate the pathophysiology, treatment, and prevention of post-traumatic osteoarthritis.Small animal models to understand pathogenesis of osteoarthritis and use of stem cell in cartilage regeneration.Initial application of EPIC-μCT to assess mouse articular cartilage morphology and composition: effects of aging and treadmill running.Synchrotron- and laboratory-based X-ray phase-contrast imaging for imaging mouse articular cartilage in the absence of radiopaque contrast agents.Novel synovial fluid recovery method allows for quantification of a marker of arthritis in mice.Activation of interleukin-1 signaling cascades in normal and osteoarthritic articular cartilage.A novel in vivo murine model of cartilage regeneration. Age and strain-dependent outcome after joint surface injury.DNA demethylation at specific CpG sites in the IL1B promoter in response to inflammatory cytokines in human articular chondrocytesFinite Element Analysis of Meniscal Anatomical 3D Scaffolds: Implications for Tissue Engineering.Rapid, automated imaging of mouse articular cartilage by microCT for early detection of osteoarthritis and finite element modelling of joint mechanics.Vanilloid receptor TRPV1-mediated phosphorylation of ERK in murine adjuvant arthritis.HMGB proteins and arthritis.In vivo effect of opticin deficiency in cartilage in a surgically induced mouse model of osteoarthritis.
P2860
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P2860
In vivo osteoarthritis target validation utilizing genetically-modified mice.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
In vivo osteoarthritis target validation utilizing genetically-modified mice.
@ast
In vivo osteoarthritis target validation utilizing genetically-modified mice.
@en
type
label
In vivo osteoarthritis target validation utilizing genetically-modified mice.
@ast
In vivo osteoarthritis target validation utilizing genetically-modified mice.
@en
prefLabel
In vivo osteoarthritis target validation utilizing genetically-modified mice.
@ast
In vivo osteoarthritis target validation utilizing genetically-modified mice.
@en
P1433
P1476
In vivo osteoarthritis target validation utilizing genetically-modified mice.
@en
P2093
Sonya S Glasson
P304
P356
10.2174/138945007779940061
P577
2007-02-01T00:00:00Z