XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells - Wikidata - wikimedia - TriplyDB

XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells

XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells

http://www.wikidata.org/entity/Q36739979

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Signal peptide peptidase functions in ERAD to cleave the unfolded protein response regulator XBP1u HLA-B27 misfolding and ankylosing spondylitis Involvement of the IRE1α-XBP1 pathway and XBP1s-dependent transcriptional reprogramming in metabolic diseases The regulation of the autophagic network and its implications for human disease Epigenetic regulation of autophagy by the methyltransferase EZH2 through an MTOR-dependent pathway Lack of XBP-1 impedes murine cytomegalovirus gene expression.UPR, autophagy, and mitochondria crosstalk underlies the ER stress response Histone deacetylase inhibitors induce autophagy through FOXO1-dependent pathways.Interplay of endoplasmic reticulum stress and autophagy in neurodegenerative disorders.MIST1 Links Secretion and Stress as Both Target and Regulator of the UPR.The XBP1 Arm of the Unfolded Protein Response Induces Fibrogenic Activity in Hepatic Stellate Cells Through Autophagy Survival or death: disequilibrating the oncogenic and tumor suppressive autophagy in cancer.Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases.The transcription factor X-box binding protein-1 in neurodegenerative diseases.How to control self-digestion: transcriptional, post-transcriptional, and post-translational regulation of autophagy.Targeting Glutamine Induces Apoptosis: A Cancer Therapy Approach.Stress management by autophagy: Implications for chemoresistance.Overexpression of microRNA-96-5p inhibits autophagy and apoptosis and enhances the proliferation, migration and invasiveness of human breast cancer cells.The unfolded protein response in skeletal development and homeostasis.FBXW7-Induced MTOR Degradation Forces Autophagy to Counteract Persistent Prion Infection.The Endoplasmic Reticulum Unfolded Protein Response in Neurodegenerative Disorders and Its Potential Therapeutic Significance Unspliced XBP1 controls autophagy through FoxO1.XBP1-FoxO1 interaction regulates ER stress-induced autophagy in auditory cells.Unfolded protein response transducer IRE1-mediated signaling independent of XBP1 mRNA splicing is not required for growth and development of medaka fish.Aβ42 oligomers modulate β-secretase through an XBP-1s-dependent pathway involving HRD1.Identification of XBP1-u as a novel regulator of the MDM2/p53 axis using an shRNA library.PTK2-mediated degradation of ATG3 impedes cancer cells susceptible to DNA damage treatment.bZIP17 and bZIP60 Regulate the Expression of BiP3 and Other Salt Stress Responsive Genes in an UPR-Independent Manner inArabidopsis thaliana

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XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells

http://www.wikidata.org/entity/Q36739979

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

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2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

@zh

2013年论文

@zh-cn

name

XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells

@ast

XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells

@en

type

label

XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells

@ast

XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells

@en

prefLabel

XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells

@ast

XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells

@en

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XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells

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Dan Xie

http://www.w3.org/2001/XMLSchema#string

Fu-Zheng Wei

http://www.w3.org/2001/XMLSchema#string

Jing Yang

http://www.w3.org/2001/XMLSchema#string

Jingyi Zhou

http://www.w3.org/2001/XMLSchema#string

Ke Ma

http://www.w3.org/2001/XMLSchema#string

Lina Wang

http://www.w3.org/2001/XMLSchema#string

Mu-Yan Cai

http://www.w3.org/2001/XMLSchema#string

Wan Fu

http://www.w3.org/2001/XMLSchema#string

Xue Li

http://www.w3.org/2001/XMLSchema#string

Ying Zhao

http://www.w3.org/2001/XMLSchema#string

P2860

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response

Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy

Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation

A C. elegans mutant that lives twice as long as wild type

Induction of autophagy and inhibition of tumorigenesis by beclin 1

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

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10.1038/CR.2013.2

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4

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23

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23277279

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