Association of human leukocyte antigen alleles and nevirapine hypersensitivity in a Malawian HIV-infected population. - Wikidata - wikimedia - TriplyDB

Association of human leukocyte antigen alleles and nevirapine hypersensitivity in a Malawian HIV-infected population.

Association of human leukocyte antigen alleles and nevirapine hypersensitivity in a Malawian HIV-infected population.

http://www.wikidata.org/entity/Q36740238

about

Genetic testing for prevention of severe drug-induced skin rash Human Leukocyte Antigen Diversity: A Southern African Perspective Evolving models of the immunopathogenesis of T cell-mediated drug allergy: The role of host, pathogens, and drug response.Perspectives on pharmacogenomics of antiretroviral medications and HIV-associated comorbidities Fever, rash, and systemic symptoms: understanding the role of virus and HLA in severe cutaneous drug allergy.The Importance of Patient-Specific Factors for Hepatic Drug Response and Toxicity Human leucocyte antigen-adverse drug reaction associations: from a perspective of ethnicity.Pharmacogenomics of off-target adverse drug reactions.Genotyping for severe drug hypersensitivity.Genome-wide association study of nevirapine hypersensitivity in a sub-Saharan African HIV-infected population.Antiviral drug allergy.CYP2B6 c.983T>C polymorphism is associated with nevirapine hypersensitivity in Malawian and Ugandan HIV populations.T cell-mediated hypersensitivity reactions to drugs Pharmacogenomics of antimicrobial agents.Genome-Wide Scan and Test of Candidate Genes in the Snail Biomphalaria glabrata Reveal New Locus Influencing Resistance to Schistosoma mansoni.Antimicrobial stewardship's new weapon? A review of antibiotic allergy and pathways to 'de-labeling'.Population pharmacokinetic and pharmacogenetic analysis of nevirapine in hypersensitive and tolerant HIV-infected patients from Malawi.The HLA-A*31:01 allele: influence on carbamazepine treatment Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: An Update.Stevens-Johnson syndrome and toxic epidermal necrolysis: an update on pharmacogenetics studies in drug-induced severe skin reaction.Advances in the Pharmacogenomics of Adverse Drug Reactions.A web resource for mining HLA associations with adverse drug reactions: HLA-ADR Association of the HLA-B*53:01 Allele With Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) Syndrome During Treatment of HIV Infection With Raltegravir.A pharmacogenetics study in Mozambican patients treated with nevirapine: full resequencing of TRAF3IP2 gene shows a novel association with SJS/TEN susceptibility Shared peptide binding of HLA Class I and II alleles associate with cutaneous nevirapine hypersensitivity and identify novel risk alleles.Impact of glutathione transferases genes polymorphisms in nevirapine adverse reactions: a possible role for GSTM1 in SJS/TEN susceptibility.Transcriptional profiling suggests that Nevirapine and Ritonavir cause drug induced liver injury through distinct mechanisms in primary human hepatocytes.Frequencies of immune hypersensitivity reaction-associated HLA class I alleles in healthy South African Indian and mixed ancestry populations determined by a novel real-time PCR assay.HLAs: Key regulators of T-cell-mediated drug hypersensitivity.SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation.Institutional profile: the Wolfson Centre for Personalised Medicine, University of Liverpool, Liverpool, UK.An Updated Review of the Molecular Mechanisms in Drug Hypersensitivity.HCP5 genetic variant (RS3099844) contributes to Nevirapine-induced Stevens Johnsons Syndrome/Toxic Epidermal Necrolysis susceptibility in a population from Mozambique.Interaction of Nevirapine with the Peptide Binding Groove of HLA-DRB1*01:01 and Its Effect on the Conformation of HLA-Peptide Complex.Critical assessment of approaches for molecular docking to elucidate associations of HLA alleles with adverse drug reactions Pharmacogenetic Markers of Drug Hypersensitivity in a Thai Population

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P2860

Association of human leukocyte antigen alleles and nevirapine hypersensitivity in a Malawian HIV-infected population.

http://www.wikidata.org/entity/Q36740238

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Clinical Infectious Diseases

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Association of human leukocyte ...... awian HIV-infected population.

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Ana Alfirevic

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Andrea L Jorgensen

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Elena Cornejo Castro

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Joep J van Oosterhout

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Mas Chaponda

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Saye H Khoo

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P2860

Stavudine, lamivudine and nevirapine combination therapy for treatment of HIV infection and AIDS in adults

HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol

Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire

HLA and HIV-1: heterozygote advantage and B*35-Cw*04 disadvantage

Medical genetics: a marker for Stevens-Johnson syndrome

PyPop: a software framework for population genomics: analyzing large-scale multi-locus genotype data.

Quantifying the metabolic activation of nevirapine in patients by integrated applications of NMR and mass spectrometries

Nevirapine and the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis.

Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir.

HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans

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Munir Pirmohamed

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Robert Heyderman

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235383568

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