Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies
about
Erythropoietin and diabetes mellitusErythropoietin: new directions for the nervous systemShedding new light on neurodegenerative diseases through the mammalian target of rapamycinErythropoietin and mTOR: A "One-Two Punch" for Aging-Related Disorders Accompanied by Enhanced Life ExpectancyNovel applications of trophic factors, Wnt and WISP for neuronal repair and regeneration in metabolic diseaseOptimal neuroprotection by erythropoietin requires elevated expression of its receptor in neuronsA new agonist of the erythropoietin receptor, Epobis, induces neurite outgrowth and promotes neuronal survivalAge-associated expression of erythropoietin and its receptor in rat spiral ganglion neurons and its association with neuronal apoptosis and hearing alterations.Otoprotective effects of erythropoietin on Cdh23erl/erl miceFoxO3a governs early microglial proliferation and employs mitochondrial depolarization with caspase 3, 8, and 9 cleavage during oxidant induced apoptosis.Oxidative stress: Biomarkers and novel therapeutic pathways.New strategies for Alzheimer's disease and cognitive impairment.Diabetes mellitus: channeling care through cellular discoverySystemic and Cerebral Vascular Endothelial Growth Factor Levels Increase in Murine Cerebral Malaria along with Increased Calpain and Caspase Activity and Can be Reduced by Erythropoietin Treatment.FOXO3a governs early and late apoptotic endothelial programs during elevated glucose through mitochondrial and caspase signaling.The "O" class: crafting clinical care with FoxO transcription factors.Early apoptotic vascular signaling is determined by Sirt1 through nuclear shuttling, forkhead trafficking, bad, and mitochondrial caspase activation.Wnt1, FoxO3a, and NF-kappaB oversee microglial integrity and activation during oxidant stress.Wnt1 neuroprotection translates into improved neurological function during oxidant stress and cerebral ischemia through AKT1 and mitochondrial apoptotic pathways.PRAS40 is an integral regulatory component of erythropoietin mTOR signaling and cytoprotectionPerinatal hypoxic-ischemic encephalopathy.Novel avenues of drug discovery and biomarkers for diabetes mellitus.Standardized environmental enrichment supports enhanced brain plasticity in healthy rats and prevents cognitive impairment in epileptic rats.Generation of biologically active multi-sialylated recombinant human EPOFc in plants.EPO relies upon novel signaling of Wnt1 that requires Akt1, FoxO3a, GSK-3β, and β-catenin to foster vascular integrity during experimental diabetes.High-dose erythropoietin in acute ST-segment elevation myocardial infarction: a meta-analysis of randomized controlled trials.Erythropoietin-derived nonerythropoietic peptide ameliorates experimental autoimmune neuritis by inflammation suppression and tissue protection.Erythropoietin employs cell longevity pathways of SIRT1 to foster endothelial vascular integrity during oxidant stress.Mammalian target of rapamycin: hitting the bull's-eye for neurological disorders.Isotretinoin and FoxO1: A scientific hypothesis.Translating cell survival and cell longevity into treatment strategies with SIRT1Targeting cardiovascular disease with novel SIRT1 pathways.Erythropoietin and Wnt1 govern pathways of mTOR, Apaf-1, and XIAP in inflammatory microglia.SIRT1: new avenues of discovery for disorders of oxidative stressPrevention of β-amyloid degeneration of microglia by erythropoietin depends on Wnt1, the PI 3-K/mTOR pathway, Bad, and Bcl-xL.Regeneration in the nervous system with erythropoietinOxidant stress and signal transduction in the nervous system with the PI 3-K, Akt, and mTOR cascadeNovel directions for diabetes mellitus drug discoveryCharting a course for erythropoietin in traumatic brain injury.Erythropoietin and oxidative stress.
P2860
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P2860
Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies
@ast
Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies
@en
type
label
Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies
@ast
Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies
@en
prefLabel
Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies
@ast
Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies
@en
P2093
P2860
P1476
Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies
@en
P2093
Kenneth Maiese
Yan Chen Shang
Zhao Zhong Chong
P2860
P304
P356
10.1016/J.PNEUROBIO.2008.02.002
P577
2008-03-04T00:00:00Z