A comprehensive approach to zinc-finger recombinase customization enables genomic targeting in human cells
about
Cas9 as a versatile tool for engineering biologySelection platforms for directed evolution in synthetic biologyExpanding the scope of site-specific recombinases for genetic and metabolic engineeringZFN, TALEN, and CRISPR/Cas-based methods for genome engineeringThe CRISPR/Cas9 system efficiently reverts the tumorigenic ability of BCR/ABL in vitro and in a xenograft model of chronic myeloid leukemia.Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies.Redesigning Recombinase Specificity for Safe Harbor Sites in the Human GenomeTargeted genome regulation via synthetic programmable transcriptional regulators.Transcription activator like effector (TALE)-directed piggyBac transposition in human cellsA programmable Cas9-serine recombinase fusion protein that operates on DNA sequences in mammalian cellsThe Development of TALE Nucleases for Biotechnology.Expanding the zinc-finger recombinase repertoire: directed evolution and mutational analysis of serine recombinase specificity determinants.Enhancing the specificity of recombinase-mediated genome engineering through dimer interface redesign.Nuclease-mediated genome editing: At the front-line of functional genomics technology.Recent advances in developing molecular tools for targeted genome engineering of mammalian cells.Human Induced Pluripotent Stem Cells as a Platform for Personalized and Precision Cardiovascular Medicine.Engineering and Application of Zinc Finger Proteins and TALEs for Biomedical Research.MegaTevs: single-chain dual nucleases for efficient gene disruption.Beyond editing to writing large genomes.Engineering altered protein-DNA recognition specificity.
P2860
Q24564294-50D4870D-909E-4692-B07B-9BF45B0C2AAEQ26741325-A29D04D3-F4B9-4E78-914F-15B0FE170D0AQ26995224-C933CC55-6918-401A-8BA0-0402190B96B1Q29615505-A29529B0-7A93-4AED-A7AD-4533367AFDC9Q33688509-29E95AA0-642B-41BF-B10B-0C0F069DFE83Q34070213-9ACDDC2F-9A2A-42C7-B686-E290A21AACEDQ35790419-C6E5BAB5-6059-4C8B-8B90-F38D44FEA8C5Q35993731-8CF223BA-CC54-4295-97B7-072DB28FAB36Q37236764-F8FF88DF-F22E-4121-B584-EAB8B37F7A20Q37522969-D59F5622-A43F-47DF-BAB5-10CA62B8BDB3Q37652116-97F9AEB5-7649-446A-B2E5-E3AFD84D61F5Q37701251-D3E390C7-9A99-4F8C-8696-048CC5618E93Q37701711-859CCD9C-BF8C-44CD-85DB-54BF936387ECQ38175498-EA57A028-731B-4321-9D14-40B136957BBDQ38238012-CF5308D6-BE68-4D80-90EC-FBE80105EE7DQ38874111-A849AA35-98C7-4C18-93AC-2A631A48BFF2Q41600298-69420F04-EFD8-4961-851E-D3F8E15F3E64Q42726265-2311BD6F-9224-4A3D-A414-7F9C60C80C13Q47324234-467152A2-E323-4E17-BA8C-2AAA351EF533Q55359800-01B0F3CE-AC38-47E9-960F-F90B9277F6E2
P2860
A comprehensive approach to zinc-finger recombinase customization enables genomic targeting in human cells
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
A comprehensive approach to zi ...... nomic targeting in human cells
@ast
A comprehensive approach to zi ...... nomic targeting in human cells
@en
type
label
A comprehensive approach to zi ...... nomic targeting in human cells
@ast
A comprehensive approach to zi ...... nomic targeting in human cells
@en
prefLabel
A comprehensive approach to zi ...... nomic targeting in human cells
@ast
A comprehensive approach to zi ...... nomic targeting in human cells
@en
P2093
P2860
P356
P1476
A comprehensive approach to zi ...... nomic targeting in human cells
@en
P2093
Carlos F Barbas
Heather L Smith
Shannon J Sirk
Thomas Gaj
P2860
P304
P356
10.1093/NAR/GKT071
P407
P577
2013-02-07T00:00:00Z