Early endosomal abnormalities and cholinergic neuron degeneration in amyloid-β protein precursor transgenic mice.
about
Dissecting Alzheimer disease in Down syndrome using mouse modelsLysosomal dysfunction in the brain of a mouse model with intraneuronal accumulation of carboxyl terminal fragments of the amyloid precursor protein.PERK mediates eIF2α phosphorylation responsible for BACE1 elevation, CREB dysfunction and neurodegeneration in a mouse model of Alzheimer's disease.A combination Alzheimer's therapy targeting BACE1 and neprilysin in 5XFAD transgenic mice.Partial BACE1 reduction in a Down syndrome mouse model blocks Alzheimer-related endosomal anomalies and cholinergic neurodegeneration: role of APP-CTF.The effect of the top 20 Alzheimer disease risk genes on gray-matter density and FDG PET brain metabolism.Neuronal signaling through endocytosis.Amyloid precursor protein and endosomal-lysosomal dysfunction in Alzheimer's disease: inseparable partners in a multifactorial disease.Dysregulation of neurotrophin signaling in the pathogenesis of Alzheimer disease and of Alzheimer disease in Down syndrome.The Endosomal-Lysosomal Pathway Is Dysregulated by APOE4 Expression in Vivo.Dysfunction of autophagy and endosomal-lysosomal pathways: Roles in pathogenesis of Down syndrome and Alzheimer's Disease.
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P2860
Early endosomal abnormalities and cholinergic neuron degeneration in amyloid-β protein precursor transgenic mice.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
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2013年论文
@zh-cn
name
Early endosomal abnormalities ...... ein precursor transgenic mice.
@ast
Early endosomal abnormalities ...... ein precursor transgenic mice.
@en
type
label
Early endosomal abnormalities ...... ein precursor transgenic mice.
@ast
Early endosomal abnormalities ...... ein precursor transgenic mice.
@en
prefLabel
Early endosomal abnormalities ...... ein precursor transgenic mice.
@ast
Early endosomal abnormalities ...... ein precursor transgenic mice.
@en
P2093
P2860
P356
P1476
Early endosomal abnormalities ...... ein precursor transgenic mice.
@en
P2093
Efrat Levy
Gurjinder Kaur
Jennifer H K Choi
Jose Morales-Corraliza
Matthew J Mazzella
P2860
P304
P356
10.3233/JAD-122143
P50
P577
2013-01-01T00:00:00Z