Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.
about
Genome-Wide Meta-Analysis of Sciatica in Finnish PopulationGene-Diet Interaction and Precision Nutrition in ObesityLD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis.The biomarker and causal roles of homoarginine in the development of cardiometabolic diseases: an observational and Mendelian randomization analysis.Selection in Europeans on Fatty Acid Desaturases Associated with Dietary ChangesGenetic variants including markers from the exome chip and metabolite traits of type 2 diabetes.Metabolic profiling of pregnancy: cross-sectional and longitudinal evidence.Metabolic profiling of alcohol consumption in 9778 young adultsMetabolomics based markers predict type 2 diabetes in a 14-year follow-up study.Lipoprotein(a) and the risk of cardiovascular disease in the European population: results from the BiomarCaRE consortium.Phenotypic Characterization of Genetically Lowered Human Lipoprotein(a) Levels.Non-targeted metabolomics combined with genetic analyses identifies bile acid synthesis and phospholipid metabolism as being associated with incident type 2 diabetes.Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation.Association of Genetic Variants Related to CETP Inhibitors and Statins With Lipoprotein Levels and Cardiovascular Risk.Metabolic profiling-multitude of technologies with great research potential, but (when) will translation emerge?NMR window of molecular complexity showing homeostasis in superorganisms.Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.Metabolic Profiling of Adiponectin Levels in Adults: Mendelian Randomization Analysis.Real-life helping behaviours in North America: A genome-wide association approach.DHA mediates the protective effect of fish consumption on new episodes of depression among women.Quantitative Serum Nuclear Magnetic Resonance Metabolomics in Large-Scale Epidemiology: A Primer on -Omic Technologies.Mendelian Randomization Analysis Identifies CpG Sites as Putative Mediators for Genetic Influences on Cardiovascular Disease Risk.Genetic Support for a Causal Role of Insulin Resistance on Circulating Branched-Chain Amino Acids and Inflammation.Whole-exome sequencing identifies common and rare variant metabolic QTLs in a Middle Eastern population.A Decade of Genetic and Metabolomic Contributions to Type 2 Diabetes Risk Prediction.The role of lipoprotein (a) in chronic kidney disease.Lipids, Lipoproteins, and Metabolites and Risk of Myocardial Infarction and Stroke.Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.Metabolic characterization of menopause: cross-sectional and longitudinal evidence.Genetic evidence of a causal effect of insulin resistance on branched-chain amino acid levels.NAFLD risk alleles in PNPLA3, TM6SF2, GCKR, and LYPLAL1 show divergent metabolic effects.Metabolomics insights into early type 2 diabetes pathogenesis and detection in individuals with normal fasting glucose.PheWAS and Beyond: The Landscape of Associations with Medical Diagnoses and Clinical Measures across 38,662 Individuals from Geisinger.Identification of seven novel loci associated with amino acid levels using single-variant and gene-based tests in 8545 Finnish men from the METSIM study.Organic cation transporter 1 (OCT1) modulates multiple cardiometabolic traits through effects on hepatic thiamine content.Causal Pathways from Blood Pressure to Larger Qrs Amplitudes a Mendelian Randomization Study.Prioritising Risk Factors for Type 2 Diabetes: Causal Inference through Genetic Approaches.Evaluation and application of summary statistic imputation to discover new height-associated loci.The MR-Base platform supports systematic causal inference across the human phenome.Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries.
P2860
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P2860
Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Genome-wide study for circulat ...... novel systemic effects of LPA.
@en
type
label
Genome-wide study for circulat ...... novel systemic effects of LPA.
@en
prefLabel
Genome-wide study for circulat ...... novel systemic effects of LPA.
@en
P2093
P2860
P50
P356
P1476
Genome-wide study for circulat ...... novel systemic effects of LPA.
@en
P2093
Anika Vaarhorst
Anton J M de Craen
Antti-Pekka Sarin
Aswin Verhoeven
Ayşe Demirkan
Elisabeth M van Leeuwen
Evelin Mihailov
Harmen H M Draisma
Joris Deelen
Ko Willems van Dijk
P2860
P2888
P356
10.1038/NCOMMS11122
P407
P50
P577
2016-03-23T00:00:00Z