Genomic and functional characterizations of phosphodiesterase subtype 4D in human cancers
about
The cAMP phosphodiesterase-4D7 (PDE4D7) is downregulated in androgen-independent prostate cancer cells and mediates proliferation by compartmentalising cAMP at the plasma membrane of VCaP prostate cancer cellsGenomic and molecular characterization of esophageal squamous cell carcinomaHarnessing protein kinase A activation to induce mesenchymal-epithelial programs to eliminate chemoresistant, tumor-initiating breast cancer cellsAdvances in targeting cyclic nucleotide phosphodiesterasesKnockdown of phosphodiesterase 4D inhibits nasopharyngeal carcinoma proliferation via the epidermal growth factor receptor signaling pathway.Cyclic nucleotide phosphodiesterases: important signaling modulators and therapeutic targets.MITF in melanoma: mechanisms behind its expression and activity.Establishment of a New Ovarian Cancer Cell Line CA5171Inactivation of oncogenic cAMP-specific phosphodiesterase 4D by miR-139-5p in response to p53 activation.Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instabilityLoss of phosphodiesterase 4D mediates acquired triapine resistance via Epac-Rap1-Integrin signaling.Human PDE4D isoform composition is deregulated in primary prostate cancer and indicative for disease progression and development of distant metastases.An exome-wide analysis of low frequency and rare variants in relation to risk of breast cancer in African American Women: the AMBER Consortium.Epac1, PDE4, and PKC protein expression and their association with AKAP95, Cx43, and cyclinD2/E1 in breast cancer tissuesPhosphodiesterase 4D inhibitors limit prostate cancer growth potential.Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors.PDE4D promotes FAK-mediated cell invasion in BRAF-mutated melanoma.Transcription Factor Trps1 Promotes Tubular Cell Proliferation after Ischemia-Reperfusion Injury through cAMP-Specific 3',5'-Cyclic Phosphodiesterase 4D and AKT.
P2860
Q28307581-45119C7A-1BDF-4E79-90FE-3CAD3E5B44B3Q28657686-5C8EDFD1-4320-4CE0-8CFE-24FF45C8283BQ33865464-B74BBC20-9FC1-4C4D-B849-F52D20C1140BQ34139490-E523C5BF-597B-42F9-B7CA-8ACC40683021Q34292964-FD32271C-0C5C-433F-B306-D4436CAA45C8Q34765802-C3103A73-6B64-4BCB-9623-88E4AC8F6E87Q35187734-EEF53866-F373-484A-AE00-43440767DBCDQ35853156-999C083F-F84A-4291-A3D9-73870EA9D06DQ37123841-8FF8C058-7940-4EC9-A4BC-E7717FA01ABDQ37550193-7DF06E36-E0DF-45A9-B733-D5A9D3FE49BBQ37708984-D384CA98-2D53-451D-940B-1F159BDC1CB0Q39341456-DC61CB2D-62DD-479B-9102-A45D270CD40CQ39706039-9EE7EDE8-B084-4E62-894A-132B67921F6BQ41601408-7B4FA334-2A15-4587-AFC9-483F4E1C02DCQ41980556-0E4AD4C3-D9F7-4E86-BE94-16C94A1A3402Q45988269-F4168293-B38F-45F0-9E4C-FDDAA8602EBDQ51188245-5C92BCD2-4EC8-4852-B218-1D74E7E0E0A8Q51611606-5F3A6342-7E04-4373-91C7-635CEC61C223
P2860
Genomic and functional characterizations of phosphodiesterase subtype 4D in human cancers
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Genomic and functional characterizations of phosphodiesterase subtype 4D in human cancers
@ast
Genomic and functional characterizations of phosphodiesterase subtype 4D in human cancers
@en
type
label
Genomic and functional characterizations of phosphodiesterase subtype 4D in human cancers
@ast
Genomic and functional characterizations of phosphodiesterase subtype 4D in human cancers
@en
prefLabel
Genomic and functional characterizations of phosphodiesterase subtype 4D in human cancers
@ast
Genomic and functional characterizations of phosphodiesterase subtype 4D in human cancers
@en
P2093
P2860
P356
P1476
Genomic and functional characterizations of phosphodiesterase subtype 4D in human cancers
@en
P2093
Arjun Sharma
Beth Y Karlan
Craig J Thomas
Daniel Chan
De-Chen Lin
H Phillip Koeffler
Henry Yang
Hongmao Sun
Jay Vadgama
P2860
P304
P356
10.1073/PNAS.1218206110
P407
P577
2013-03-27T00:00:00Z