Maintenance of fork integrity at damaged DNA and natural pause sites.
about
RNAi-based screening identifies the Mms22L-Nfkbil2 complex as a novel regulator of DNA replication in human cells.Repriming of DNA synthesis at stalled replication forks by human PrimPolTranscription termination maintains chromosome integrityLinking replication stress with heterochromatin formationDNA polymerase delta in DNA replication and genome maintenanceTimeless links replication termination to mitotic kinase activationMolecular mimicry of SUMO promotes DNA repairNew functions of Ctf18-RFC in preserving genome stability outside its role in sister chromatid cohesion.An N-terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks.A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase alpha within the eukaryotic replisome.Mrc1, Tof1 and Csm3 inhibit CAG.CTG repeat instability by at least two mechanisms.Rtt101 and Mms1 in budding yeast form a CUL4(DDB1)-like ubiquitin ligase that promotes replication through damaged DNACheckpoint effects and telomere amplification during DNA re-replication in fission yeast.RecQ helicases: guardian angels of the DNA replication fork.Low levels of DNA polymerase alpha induce mitotic and meiotic instability in the ribosomal DNA gene cluster of Saccharomyces cerevisiae.Segmental duplications arise from Pol32-dependent repair of broken forks through two alternative replication-based mechanisms.HARPing on about the DNA damage response during replication.FANCM regulates DNA chain elongation and is stabilized by S-phase checkpoint signalling.Is homologous recombination really an error-free process?Continued primer synthesis at stalled replication forks contributes to checkpoint activation.Topoisomerase I suppresses genomic instability by preventing interference between replication and transcriptionGenome-wide mapping of nuclear mitochondrial DNA sequences links DNA replication origins to chromosomal double-strand break formation in Schizosaccharomyces pombe.Genome stability control by checkpoint regulation of tRNA gene transcription.Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site.Minichromosome maintenance proteins interact with checkpoint and recombination proteins to promote s-phase genome stability.Replication fork stalling by bulky DNA damage: localization at active origins and checkpoint modulationRoles of the Werner syndrome RecQ helicase in DNA replication.dNTP pool levels modulate mutator phenotypes of error-prone DNA polymerase ε variants.Cdk5 promotes DNA replication stress checkpoint activation through RPA-32 phosphorylation, and impacts on metastasis free survival in breast cancer patients.Colocalization of Mec1 and Mrc1 is sufficient for Rad53 phosphorylation in vivo.Instability of (CTG)n•(CAG)n trinucleotide repeats and DNA synthesisHuman telomeres replicate using chromosome-specific, rather than universal, replication programs.Mutations Affecting Potassium Import Restore the Viability of the Escherichia coli DNA Polymerase III holD MutantBudding Yeast Rif1 Controls Genome Integrity by Inhibiting rDNA ReplicationMutations in the Non-Catalytic Subunit Dpb2 of DNA Polymerase Epsilon Affect the Nrm1 Branch of the DNA Replication Checkpoint.Regulation of rtt107 recruitment to stalled DNA replication forks by the cullin rtt101 and the rtt109 acetyltransferase.The Role of Mms22p in DNA Damage Response in Candida albicans.Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response.Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stressRAD53 is limiting in double-strand break repair and in protection against toxicity associated with ribonucleotide reductase inhibition
P2860
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P2860
Maintenance of fork integrity at damaged DNA and natural pause sites.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Maintenance of fork integrity at damaged DNA and natural pause sites.
@ast
Maintenance of fork integrity at damaged DNA and natural pause sites.
@en
type
label
Maintenance of fork integrity at damaged DNA and natural pause sites.
@ast
Maintenance of fork integrity at damaged DNA and natural pause sites.
@en
prefLabel
Maintenance of fork integrity at damaged DNA and natural pause sites.
@ast
Maintenance of fork integrity at damaged DNA and natural pause sites.
@en
P1433
P1476
Maintenance of fork integrity at damaged DNA and natural pause sites.
@en
P2093
Hélène Tourrière
P304
P356
10.1016/J.DNAREP.2007.02.004
P577
2007-03-26T00:00:00Z