Improved antitumor activity and tumor targeting of NH(2)-terminal-specific PEGylated tumor necrosis factor-related apoptosis-inducing ligand. - Wikidata - wikimedia - TriplyDB

Improved antitumor activity and tumor targeting of NH(2)-terminal-specific PEGylated tumor necrosis factor-related apoptosis-inducing ligand.

Improved antitumor activity and tumor targeting of NH(2)-terminal-specific PEGylated tumor necrosis factor-related apoptosis-inducing ligand.

http://www.wikidata.org/entity/Q36777316

about

Onto better TRAILs for cancer treatment A novel capsid-modified oncolytic recombinant adenovirus type 5 for tumor-targeting gene therapy by intravenous route PEGylated apoptotic protein-loaded PLGA microspheres for cancer therapy.Piperlongumine and immune cytokine TRAIL synergize to promote tumor death Delivery of tumor-homing TRAIL sensitizer with long-acting TRAIL as a therapy for TRAIL-resistant tumors.Smad7 protein induces interferon regulatory factor 1-dependent transcriptional activation of caspase 8 to restore tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis Multiplex imaging of an intracellular proteolytic cascade by using a broad-spectrum nanoquencher.PEG-transferrin conjugated TRAIL (TNF-related apoptosis-inducing ligand) for therapeutic tumor targeting.Systemic PEGylated TRAIL treatment ameliorates liver cirrhosis in rats by eliminating activated hepatic stellate cells.Mix to validate: a facile, reversible PEGylation for fast screening of potential therapeutic proteins in vivo.Improved antitumor activity of TRAIL fusion protein via formation of self-assembling nanoparticle.Preclinical study of rAAV2-sTRAIL: pharmaceutical efficacy, biodistribution and safety in animals.Claudin-7 suppresses the cytotoxicity of TRAIL-expressing mesenchymal stem cells in H460 human non-small cell lung cancer cells.Targeted Delivery to Tumor-associated Pericytes via an Affibody with High Affinity for PDGFRβ Enhances the in vivo Antitumor Effects of Human TRAIL.TRAIL-coated leukocytes that prevent the bloodborne metastasis of prostate cancer.Paving the TRAIL to anti-fibrotic therapy Pegylated TRAIL retains anti-leukemic cytotoxicity and exhibits improved signal transduction activity with respect to TRAIL.Nanoparticles for Immune Cytokine TRAIL-Based Cancer Therapy.Cancer preventive effect of recombinant TRAIL by ablation of oncogenic inflammation in colitis-associated cancer rather than anticancer effect.Nanocarriers for TRAIL delivery: driving TRAIL back on track for cancer therapy.Evaluation of interstitial protein delivery in multicellular layers model.Endogenous IgG-based affinity-controlled release of TRAIL exerts superior antitumor effects.

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P2860

Improved antitumor activity and tumor targeting of NH(2)-terminal-specific PEGylated tumor necrosis factor-related apoptosis-inducing ligand.

http://www.wikidata.org/entity/Q36777316

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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2010年论文

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2010年论文

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name

Improved antitumor activity an ...... ted apoptosis-inducing ligand.

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Improved antitumor activity an ...... ted apoptosis-inducing ligand.

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Improved antitumor activity an ...... ted apoptosis-inducing ligand.

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1535-7163.MCT-09-1076

P1433

Molecular Cancer Therapeutics

P1476

Improved antitumor activity an ...... ted apoptosis-inducing ligand.

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P2093

Cheng-Hao Jin

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Dong-Gyu Jo

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Kang Choon Lee

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Kyeongsoon Park

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Sohee Son

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Su Young Chae

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Tae Hyung Kim

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Yu Seok Youn

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P2860

Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5

Identification and characterization of a new member of the TNF family that induces apoptosis

Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family

PEGylation, successful approach to drug delivery

Death receptors: signaling and modulation

Site-specific PEGylation of a lysine-deficient TNF-alpha with full bioactivity.

Functionalization of tumor necrosis factor-alpha using phage display technique and PEGylation improves its antitumor therapeutic window.

Safety and antitumor activity of recombinant soluble Apo2 ligand.

Mono-N-terminal poly(ethylene glycol)-protein conjugates.

Designed tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the DR5 receptor.

P304

1719-1729

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scholarly article

P356

10.1158/1535-7163.MCT-09-1076

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6

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9

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Kwangmeyung Kim

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2010-06-01T00:00:00Z

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44642989

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20515949

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3629964

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