about
Reconstitution of the mitochondrial Hsp70 (mortalin)-p53 interaction using purified proteins--identification of additional interacting regionsModulation of the vitamin D3 response by cancer-associated mutant p53The roles of viruses in brain tumor initiation and oncomodulationMutant p53 attenuates the SMAD-dependent transforming growth factor beta1 (TGF-beta1) signaling pathway by repressing the expression of TGF-beta receptor type IIOncogenic Intra-p53 Family Member Interactions in Human CancersTargeting Oncogenic Mutant p53 for Cancer TherapyThe p53-microRNA-34a axis regulates cellular entry receptors for tumor-associated human herpes viruses.PTEN has tumor-promoting properties in the setting of gain-of-function p53 mutations.The properties of high-dimensional data spaces: implications for exploring gene and protein expression data.Modulation of gene expression in U251 glioblastoma cells by binding of mutant p53 R273H to intronic and intergenic sequencesMutant p53 gain-of-function in cancer.Clinical outcomes and correlates of TP53 mutations and cancer.Mutant p53-induced up-regulation of mitogen-activated protein kinase kinase 3 contributes to gain of functionp53-mediated hematopoietic stem and progenitor cell competition.Altered-function p53 missense mutations identified in breast cancers can have subtle effects on transactivation.Definition of ubiquitination modulator COP1 as a novel therapeutic target in human hepatocellular carcinoma.Cell free expression of hif1α and p21 in maternal peripheral blood as a marker for preeclampsia and fetal growth restrictionPreferential binding of hot spot mutant p53 proteins to supercoiled DNA in vitro and in cells.microRNAs: short non-coding bullets of gain of function mutant p53 proteins.Specific TP53 mutations predict aggressive phenotype in head and neck squamous cell carcinoma: a retrospective archival study.Identification of potential synthetic lethal genes to p53 using a computational biology approachTP53-Associated Pediatric Malignancies.Comparison of effects of p53 null and gain-of-function mutations on salivary tumors in MMTV-Hras transgenic mice.Functional repair of p53 mutation in colorectal cancer cells using trans-splicing.TopBP1 mediates mutant p53 gain of function through NF-Y and p63/p73.The cancer-associated K351N mutation affects the ubiquitination and the translocation to mitochondria of p53 protein.Clinical implications of miRNAs in the pathogenesis, diagnosis and therapy of pancreatic cancer.Defining a role for sphingosine kinase 1 in p53-dependent tumors.Mutant p53 cooperates with ETS2 to promote etoposide resistance.MicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of functionMutant p53: one name, many proteins.N-methylpurine DNA glycosylase inhibits p53-mediated cell cycle arrest and coordinates with p53 to determine sensitivity to alkylating agents.Silencing of mutant p53 by siRNA induces cell cycle arrest and apoptosis in human bladder cancer cellsThe inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss.Mutant p53-R273H gains new function in sustained activation of EGFR signaling via suppressing miR-27a expressionAllele-specific silencing of mutant p53 attenuates dominant-negative and gain-of-function activities.Induction of genetic instability by gain-of-function p53 cancer mutants.Versatile functions of p53 protein in multicellular organismsThe dark side of a tumor suppressor: anti-apoptotic p53.Differential regulation of the REGγ-proteasome pathway by p53/TGF-β signalling and mutant p53 in cancer cells.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Transcription regulation by mutant p53.
@ast
Transcription regulation by mutant p53.
@en
type
label
Transcription regulation by mutant p53.
@ast
Transcription regulation by mutant p53.
@en
prefLabel
Transcription regulation by mutant p53.
@ast
Transcription regulation by mutant p53.
@en
P2093
P2860
P356
P1433
P1476
Transcription regulation by mutant p53.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1210294
P407
P577
2007-04-01T00:00:00Z