Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain - Wikidata - wikimedia - TriplyDB

Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain

Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain

http://www.wikidata.org/entity/Q36777990

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BAK multimerization for apoptosis, but not bid binding, is inhibited by negatively charged residue in the BAK hydrophobic groove Principles and Overview of Sampling Methods for Modeling Macromolecular Structure and Dynamics Outcome of a workshop on applications of protein models in biomedical research Hypoxia inactivates the VHL tumor suppressor through PIASy-mediated SUMO modification.Tumor suppressor p53 and estrogen receptors in nuclear-mitochondrial communication.Comparative Analyses of Transcriptional Profiles in Mouse Organs Using a Pneumonic Plague Model after Infection with Wild-Type Yersinia pestis CO92 and Its Braun Lipoprotein Mutant.BAX/BAK-independent mitoptosis during cell death induced by proteasome inhibition?Delivery of a monomeric p53 subdomain with mitochondrial targeting signals from pro-apoptotic Bak or Bax.Bak compensated for Bax in p53-null cells to release cytochrome c for the initiation of mitochondrial signaling during Withanolide D-induced apoptosis.Cancer-associated p53 tetramerization domain mutants: quantitative analysis reveals a low threshold for tumor suppressor inactivation Blockade of the BAK hydrophobic groove by inhibitory phosphorylation regulates commitment to apoptosis.Wild-type and mutant p53 proteins interact with mitochondrial caspase-3 Tid1 is a new regulator of p53 mitochondrial translocation and apoptosis in cancer.Resveratrol induces p53-independent, X-linked inhibitor of apoptosis protein (XIAP)-mediated Bax protein oligomerization on mitochondria to initiate cytochrome c release and caspase activation.The cancer-associated K351N mutation affects the ubiquitination and the translocation to mitochondria of p53 protein.The BCL-2 family reunion.Dissecting Genomic Aberrations in Myeloproliferative Neoplasms by Multiplex-PCR and Next Generation Sequencing.Curcumin induces Apaf-1-dependent, p21-mediated caspase activation and apoptosis.Decrease of mitochondrial p53 during late apoptosis is linked to its dephosphorylation on serine 20 Human Pluripotent Stem Cells and Derived Neuroprogenitors Display Differential Degrees of Susceptibility to BH3 Mimetics ABT-263, WEHI-539 and ABT-199 P53 Regulates Rapid Apoptosis in Human Pluripotent Stem Cells.Neem oil limonoids induces p53-independent apoptosis and autophagy.Mitochondria in human pluripotent stem cell apoptosis.Identification of an activation site in Bak and mitochondrial Bax triggered by antibodies.The p53 family and programmed cell death The mitochondrial p53 pathway.Quercetin induces mitochondrial mediated apoptosis and protective autophagy in human glioblastoma U373MG cells Watching the watcher: regulation of p53 by mitochondria Cytoplasmic functions of the tumour suppressor p53.Mitochondria and energetic depression in cell pathophysiology PUMA cooperates with direct activator proteins to promote mitochondrial outer membrane permeabilization and apoptosis.TRIM22-Mediated Apoptosis is Associated with Bak Oligomerization in Monocytes.Investigation on tissue specific effects of pro-apoptotic micro RNAs revealed miR-147b as a potential biomarker in ovarian cancer prognosis.Many players in BCL-2 family affairs.The cytoplasmic side of p53's oncosuppressive activities.Allosteric modulation of protein oligomerization: an emerging approach to drug design."Licensed to kill": tyrosine dephosphorylation and Bak activation.The Cell-Cycle Arrest and Apoptotic Functions of p53 in Tumor Initiation and Progression.Constitutive p53 heightens mitochondrial apoptotic priming and favors cell death induction by BH3 mimetic inhibitors of BCL-xL Resistance to UV-induced apoptosis by β-HPV5 E6 involves targeting of activated BAK for proteolysis by recruitment of the HERC1 ubiquitin ligase.

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P2860

Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain

http://www.wikidata.org/entity/Q36777990

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain

@ast

Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain

@en

type

label

Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain

@ast

Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain

@en

prefLabel

Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain

@ast

Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain

@en

P1433

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P1433

Journal of Biological Chemistry

P1476

Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain

@en

P2093

Adrian A Canutescu

http://www.w3.org/2001/XMLSchema#string

E Christine Pietsch

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Erin Perchiniak

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Guoli Wang

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Maureen E Murphy

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P2860

tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c

PUMA, a novel proapoptotic gene, is induced by p53

p53 has a direct apoptogenic role at the mitochondria

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

BID: a novel BH3 domain-only death agonist

Electrostatics of nanosystems: application to microtubules and the ribosome

A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions

The X-ray structure of a BAK homodimer reveals an inhibitory zinc binding site

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

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21294-21304

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scholarly article

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10.1074/JBC.M710539200

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P433

30

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283

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Roland Dunbrack

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2008-06-04T00:00:00Z

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18524770

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