PUMA cooperates with direct activator proteins to promote mitochondrial outer membrane permeabilization and apoptosis.
about
A Comprehensive and System Review for the Pharmacological Mechanism of Action of Rhein, an Active Anthraquinone IngredientAntagonistic regulation of apoptosis and differentiation by the Cut transcription factor represents a tumor-suppressing mechanism in DrosophilaSilencing microRNA-143 protects the integrity of the blood-brain barrier: implications for methamphetamine abuseEfficient elimination of cancer cells by deoxyglucose-ABT-263/737 combination therapyQuercetin potentiates doxorubicin mediated antitumor effects against liver cancer through p53/Bcl-xlAutophagy controls the kinetics and extent of mitochondrial apoptosis by regulating PUMA levels.Implication of TAp73 in the p53-independent pathway of Puma induction and Puma-dependent apoptosis in primary cortical neuronsTethering function of the caspase cleavage fragment of Golgi protein p115 promotes apoptosis via a p53-dependent pathway.Harnessing the p53-PUMA axis to overcome DNA damage resistance in renal cell carcinomaAdipocyte morphology and implications for metabolic derangements in acquired obesity.The Role of BH3-Only Proteins in Tumor Cell Development, Signaling, and Treatment.Regulation of memory B-cell survival by the BH3-only protein Puma.Cooperative effects of Akt-1 and Raf-1 on the induction of cellular senescence in doxorubicin or tamoxifen treated breast cancer cells.Defining the molecular signature of chemotherapy-mediated lung tumor phenotype modulation and increased susceptibility to T-cell killing.ROS/p38/p53/Puma signaling pathway is involved in emodin-induced apoptosis of human colorectal cancer cells.Activation of p21-Dependent G1/G2 Arrest in the Absence of DNA Damage as an Antiapoptotic Response to Metabolic Stress.Identifying Novel Candidate Genes Related to Apoptosis from a Protein-Protein Interaction Network.Uncoupling of PUMA Expression and Apoptosis Contributes to Functional Heterogeneity in Renal Cell Carcinoma - Prognostic and Translational ImplicationsFolate stress induces apoptosis via p53-dependent de novo ceramide synthesis and up-regulation of ceramide synthase 6Genetic disruption of Abl nuclear import reduces renal apoptosis in a mouse model of cisplatin-induced nephrotoxicityTonic activation of Bax primes neural progenitors for rapid apoptosis through a mechanism preserved in medulloblastomaLipopolysaccharide Induces Human Pulmonary Micro-Vascular Endothelial Apoptosis via the YAP Signaling Pathway.Mir143-BBC3 cascade reduces microglial survival via interplay between apoptosis and autophagy: Implications for methamphetamine-mediated neurotoxicity.Evaluation of the BH3-only protein Puma as a direct Bak activatorPUMA mediates ER stress-induced apoptosis in portal hypertensive gastropathy.TRAIL-mediated signaling in prostate, bladder and renal cancer.Subcellular localization of PUMA regulates its pro-apoptotic activity in Burkitt's lymphoma B cells.JS-K, a GST-activated nitric oxide donor prodrug, enhances chemo-sensitivity in renal carcinoma cells and prevents cardiac myocytes toxicity induced by Doxorubicin.Conserved molecular mechanisms underlying the effects of small molecule xenobiotic chemotherapeutics on cells.The Evaluation and Comparison of Transcriptionally Targeted Noxa and Puma Killer Genes to Initiate Apoptosis Under Cancer-Specific Promoter CXCR1 in Hepatocarcinoma Gene TherapyThe adaptor protein CRK is a pro-apoptotic transducer of endoplasmic reticulum stress.Synergistic Effect of Expressed miR-128 and Puma Protein on Targeted Induction of Tumor Cell ApoptosisA DR4:tBID axis drives the p53 apoptotic response by promoting oligomerization of poised BAX.Arrestins in apoptosis.Genetically defining the mechanism of Puma- and Bim-induced apoptosisMode of cell death induced by the HSP90 inhibitor 17-AAG (tanespimycin) is dependent on the expression of pro-apoptotic BAX.NVP-BKM120 inhibits colon cancer growth via FoxO3a-dependent PUMA induction.Propofol-induced neurotoxicity in hESCs involved in activation of miR-206/PUMA signal pathway.Glucose oscillations, more than constant high glucose, induce p53 activation and a metabolic memory in human endothelial cells.Actinomycin D synergistically enhances the cytotoxicity of CDDP on KB cells by activating P53 via decreasing P53-MDM2 complex.
P2860
Q27023870-473836EB-61E6-4633-AADC-56843CEDACC3Q27334525-CC8552A8-2617-4139-A8CA-3C246BDE79EEQ28392130-7C4382AB-CC55-4CF8-BED1-EB100CB7FE57Q28477131-713CBE3A-F6F6-4A3E-9380-1BDED173E801Q28484294-CCFF373F-480E-4AE3-B8AD-AF7D1603D104Q30576494-D8D2BE6D-8E76-4027-A7AB-F790EC1BE195Q34205786-0047B3DD-B4B3-4959-A126-174A928C27F5Q34624486-0AE8F5FD-7158-4FFA-B2D3-E0353C96859AQ35022460-C4D295FE-A0A9-49B5-91EB-026D4D9F16D6Q35096886-1860D626-99C6-4F9F-B7F9-8D4077D2B510Q35180339-2E579BBE-DC67-440C-B453-480B29F4C0B0Q35483598-B3410142-34FD-4056-B108-39249E38712CQ35640301-C7FB4A93-2BEC-4D8E-9D96-D67780B5EB8CQ35752182-4FEC0E87-D696-4080-B7F5-E05B974AE6F2Q35858351-E795169E-6870-4489-82C9-FAF4A575B517Q35959739-5A5F3ED8-280D-40AD-A1D5-498E7BA1768BQ36207483-DD178211-5211-4663-A789-48C3C0C2A45FQ36427522-50F53E2C-F0C5-41C7-96EA-2C7C70029AA5Q36812440-1716A4D3-57E2-426A-86EA-72EAFF668D6EQ36920825-9D0C55A0-0370-479A-8A20-CDC507F0401CQ37309527-0F45B7E4-4423-4FFD-BB54-7A7AD0C76465Q37348630-BCB3C874-6307-4386-B79A-A2B64882626CQ37371613-5626092B-BD5D-4EF9-9108-8F05B3392274Q37428715-989AF765-73F3-4DDB-AD8E-B89FBE063131Q37680278-6D56F178-D91F-4EDC-BE3D-72DD2EAC2E3EQ37889112-65AFD0AE-7E4D-4BFC-B237-324E03B3A4E7Q38262165-D5BAB7F3-53DE-4398-961E-707E6300C84DQ38700491-976B99EB-446F-488C-82AC-6239B226DC79Q38719813-9C920638-27FC-4334-A69C-CD2B8ACADB47Q38729185-84217910-FEAA-4639-9A48-2114B2FEEABAQ39426318-D3AFB5AC-5E0E-4D55-ADBE-FE87C5DC1591Q41674108-BA327262-618E-4D0E-85F4-24134F06B5B4Q41908813-131A455C-8E12-43EF-837D-9E92D3C22E33Q42089456-34E87020-DF38-455B-BE56-71E8BEA63498Q42576111-8D4578A4-15E7-4E70-9128-1FB19E636534Q42770281-019365AB-9FBD-4EAD-B29E-35938E4402BAQ47141630-5600F50C-FC99-46E5-A35A-98241CCDCCD1Q47256731-35565E21-36F3-4B82-BEE8-5B2AA7B8FAFCQ51021306-D79CAAC9-ECF7-477F-9F8A-CF594AAC6B1EQ51036881-B02B5BBD-1EED-43F3-85BF-1522FBFFD788
P2860
PUMA cooperates with direct activator proteins to promote mitochondrial outer membrane permeabilization and apoptosis.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 02 September 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
PUMA cooperates with direct ac ...... ermeabilization and apoptosis.
@en
PUMA cooperates with direct ac ...... ermeabilization and apoptosis.
@nl
type
label
PUMA cooperates with direct ac ...... ermeabilization and apoptosis.
@en
PUMA cooperates with direct ac ...... ermeabilization and apoptosis.
@nl
prefLabel
PUMA cooperates with direct ac ...... ermeabilization and apoptosis.
@en
PUMA cooperates with direct ac ...... ermeabilization and apoptosis.
@nl
P2860
P356
P1433
P1476
PUMA cooperates with direct ac ...... ermeabilization and apoptosis.
@en
P2093
Jerry E Chipuk
P2860
P304
P356
10.4161/CC.8.17.9412
P577
2009-09-02T00:00:00Z