Phenotype and function of B cells and dendritic cells from interferon regulatory factor 5-deficient mice with and without a mutation in DOCK2. - Wikidata - wikimedia - TriplyDB

Phenotype and function of B cells and dendritic cells from interferon regulatory factor 5-deficient mice with and without a mutation in DOCK2.

Phenotype and function of B cells and dendritic cells from interferon regulatory factor 5-deficient mice with and without a mutation in DOCK2.

http://www.wikidata.org/entity/Q36780004

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Dedicator of Cytokinesis 2 in Cell Signaling Regulation and Disease Development.Interferon regulatory factor-5 deficiency ameliorates disease severity in the MRL/lpr mouse model of lupus in the absence of a mutation in DOCK2.Interferon regulatory factor 5-dependent immune responses in the draining lymph node protect against West Nile virus infection.Protein kinase IKKβ-catalyzed phosphorylation of IRF5 at Ser462 induces its dimerization and nuclear translocation in myeloid cells.IRF5 deficiency ameliorates lupus but promotes atherosclerosis and metabolic dysfunction in a mouse model of lupus-associated atherosclerosis Mangiferin inhibits macrophage classical activation via downregulating interferon regulatory factor 5 expression.Promotion of Inflammatory Arthritis by Interferon Regulatory Factor 5 in a Mouse Model.Interferon-Regulatory Factor 5-Dependent Signaling Restricts Orthobunyavirus Dissemination to the Central Nervous System Specific detection of interferon regulatory factor 5 (IRF5): A case of antibody inequality.Bioinformatics analysis of the factors controlling type I IFN gene expression in autoimmune disease and virus-induced immunity.DOCK2 interacts with FLT3 and modulates the survival of FLT3-expressing leukemia cells.Interferon regulatory factor 5 and autoimmune lupus.IRF5 and IRF8 modulate the CAL-1 human plasmacytoid dendritic cell line response following TLR9 ligation.IRF5 distinguishes severe asthma in humans and drives Th1 phenotype and airway hyperreactivity in mice Striking Immune Phenotypes in Gene-Targeted Mice Are Driven by a Copy-Number Variant Originating from a Commercially Available C57BL/6 Strain TLR sensing of bacterial spore-associated RNA triggers host immune responses with detrimental effects.IRF5, IRF8, and IRF7 in human pDCs - the good, the bad, and the insignificant?Lineage-Specific Functionality of an Interferon Regulatory Factor 5 Lupus Risk Haplotype: Lack of B Cell Intrinsic Effects.Coactivation of TLR2 and TLR8 in Primary Human Monocytes Triggers a Distinct Inflammatory Signaling Response.

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Phenotype and function of B cells and dendritic cells from interferon regulatory factor 5-deficient mice with and without a mutation in DOCK2.

http://www.wikidata.org/entity/Q36780004

description

2013 nî lūn-bûn

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Phenotype and function of B ce ...... d without a mutation in DOCK2.

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Phenotype and function of B ce ...... d without a mutation in DOCK2.

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Phenotype and function of B ce ...... d without a mutation in DOCK2.

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Phenotype and function of B ce ...... d without a mutation in DOCK2.

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Phenotype and function of B ce ...... d without a mutation in DOCK2.

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Phenotype and function of B ce ...... d without a mutation in DOCK2.

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International Immunology

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Phenotype and function of B ce ...... d without a mutation in DOCK2.

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Amanda A Watkins

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Ann Marshak-Rothstein

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Ian R Rifkin

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Jessalyn M Ubellacker

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Kei Yasuda

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Kerstin Nündel

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Ramon G Bonegio

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Tania Dhawan

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P2860

Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus

Multiple regulatory domains of IRF-5 control activation, cellular localization, and induction of chemokines that mediate recruitment of T lymphocytes

Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus

The IRF family, revisited

Immunomodulatory functions of type I interferons

Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes

A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors

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295-306

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10.1093/INTIMM/DXS114

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5

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25

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3631000

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