Prevention of diabetes-induced arginase activation and vascular dysfunction by Rho kinase (ROCK) knockout. - Wikidata - wikimedia - TriplyDB

Prevention of diabetes-induced arginase activation and vascular dysfunction by Rho kinase (ROCK) knockout.

Prevention of diabetes-induced arginase activation and vascular dysfunction by Rho kinase (ROCK) knockout.

http://www.wikidata.org/entity/Q36787307

about

The Function of Rho-Associated Kinases ROCK1 and ROCK2 in the Pathogenesis of Cardiovascular Disease New approaches to the design and discovery of therapies to prevent erectile dysfunction.Elevated Glucose Levels Promote Contractile and Cytoskeletal Gene Expression in Vascular Smooth Muscle via Rho/Protein Kinase C and Actin Polymerization Tissue-specific up-regulation of arginase I and II induced by p38 MAPK mediates endothelial dysfunction in type 1 diabetes mellitus.Role of arginase in vessel wall remodeling.Arginase: the emerging therapeutic target for vascular oxidative stress and inflammation.Vasomotor regulation of coronary microcirculation by oxidative stress: role of arginase.Activated Rho kinase mediates diabetes-induced elevation of vascular arginase activation and contributes to impaired corpora cavernosa relaxation: possible involvement of p38 MAPK activation Targeting of Rho kinase ameliorates impairment of diabetic endothelial function in intrarenal artery.Rho kinases in cardiovascular physiology and pathophysiology: the effect of fasudil.Arginase as a potential target in the treatment of cardiovascular disease: reversal of arginine steal?Endothelial dysfunction and vascular disease - a 30th anniversary update.Macro- and microvascular endothelial dysfunction in diabetes.Rho-associated protein kinases as therapeutic targets for both vascular and parenchymal pathologies in Alzheimer's disease.Heterogeneous Impact of ROCK2 on Carotid and Cerebrovascular Function Role of ROCK upregulation in endothelial and smooth muscle vascular functions in diabetic rat aorta.Vessel Dilation Attenuates Endothelial Dysfunction Following Middle Cerebral Artery Occlusion in Hyperglycemic Rats.Effects of the Hydroalcoholic Extract of Zingiber officinale on Arginase I Activity and Expression in the Retina of Streptozotocin-Induced Diabetic Rats.ROCK-1 mediates diabetes-induced retinal pigment epithelial and endothelial cell blebbing: Contribution to diabetic retinopathy.Assessment of serum arginase I as a type 2 diabetes mellitus diagnosis biomarker in patients Indoxyl sulfate potentiates endothelial dysfunction via reciprocal role for reactive oxygen species and RhoA/ROCK signaling in 5/6 nephrectomized rats.Obesity-induced vascular dysfunction and arterial stiffening requires endothelial cell arginase 1.Inhibition of Rho kinase protects from ischaemia-reperfusion injury via regulation of arginase activity and nitric oxide synthase in type 1 diabetes.Amino acid metabolism reflecting arginase activity is increased in patients with type 2 diabetes and associated with endothelial dysfunction.Rho-kinase and the nitric oxide pathway modulate basilar arterial reactivity to acetylcholine and angiotensin II in streptozotocin-induced diabetic mice.Fasudil ameliorates endothelial dysfunction in streptozotocin-induced diabetic rats: a possible role of Rho kinase.Mechanisms of Diabetes-Induced Endothelial Cell Senescence: Role of Arginase 1.The level of ROCK1 and ROCK2 in patients with pulmonary hypertension in plateau area.

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Prevention of diabetes-induced arginase activation and vascular dysfunction by Rho kinase (ROCK) knockout.

http://www.wikidata.org/entity/Q36787307

description

2012 nî lūn-bûn

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name

Prevention of diabetes-induced ...... by Rho kinase (ROCK) knockout.

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Prevention of diabetes-induced ...... by Rho kinase (ROCK) knockout.

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Cardiovascular Research

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Prevention of diabetes-induced ...... by Rho kinase (ROCK) knockout

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Anil Bhatta

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Haroldo A Toque

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Lin Yao

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R William Caldwell

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Ruth B Caldwell

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Surabhi Chandra

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P2860

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

Endothelial activation by angiotensin II through NFkappaB and p38 pathways: Involvement of NFkappaB-inducible kinase (NIK), free oxygen radicals, and selective inhibition by aspirin

ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

The role of rho kinase in sex-dependent vascular dysfunction in type 1 diabetes.

Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways

Impaired endothelial function in arterial hypertension and hypercholesterolemia: potential mechanisms and differences.

p38 Mitogen-activated protein kinase (MAPK) increases arginase activity and contributes to endothelial dysfunction in corpora cavernosa from angiotensin-II-treated mice

Rho GTPase/Rho kinase negatively regulates endothelial nitric oxide synthase phosphorylation through the inhibition of protein kinase B/Akt in human endothelial cells

RhoA/Rho-kinase suppresses endothelial nitric oxide synthase in the penis: a mechanism for diabetes-associated erectile dysfunction

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10.1093/CVR/CVS371

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97

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23250919

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3633399

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