Mifepristone alters amyloid precursor protein processing to preclude amyloid beta and also reduces tau pathology.
about
Corticotropin-releasing factor receptor-1 antagonism mitigates beta amyloid pathology and cognitive and synaptic deficits in a mouse model of Alzheimer's disease.Targeting psychologic stress signaling pathways in Alzheimer's disease.Elimination of Microglia Improves Functional Outcomes Following Extensive Neuronal Loss in the Hippocampus.Is Dysregulation of the HPA-Axis a Core Pathophysiology Mediating Co-Morbid Depression in Neurodegenerative Diseases?Impact of CRFR1 Ablation on Amyloid-β Production and Accumulation in a Mouse Model of Alzheimer's Disease.Short-term modern life-like stress exacerbates Aβ-pathology and synapse loss in 3xTg-AD miceKnockout of 5-lipoxygenase prevents dexamethasone-induced tau pathology in 3xTg miceSubchronic glucocorticoid receptor inhibition rescues early episodic memory and synaptic plasticity deficits in a mouse model of Alzheimer's disease.Associations between Sleep, Cortisol Regulation, and Diet: Possible Implications for the Risk of Alzheimer Disease.The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function.Neuropathology of stress.Genetic ablation of tau mitigates cognitive impairment induced by type 1 diabetes.Microglial repopulation resolves inflammation and promotes brain recovery after injury.Cognitive Decline in Preclinical Alzheimer's Disease: Amyloid-Beta versus Tauopathy.Maternal dexamethasone exposure ameliorates cognition and tau pathology in the offspring of triple transgenic AD mice.Glucocorticoid-mediated activation of GSK3β promotes tau phosphorylation and impairs memory in type 2 diabetes.Targeting glucocorticoid receptors prevents the effects of early life stress on amyloid pathology and cognitive performance in APP/PS1 mice.A preclinical perspective on the enhanced vulnerability to Alzheimer's disease after early-life stress.Vulnerability and resilience to Alzheimer's disease: early life conditions modulate neuropathology and determine cognitive reserveCentral Role of Glucocorticoid Receptors in Alzheimer's Disease and Depression
P2860
Q30754529-C148283C-9DF7-455A-8DB2-2B6446EF6022Q33820375-822DF72F-169A-4E02-8366-CF02264E2164Q34671403-66907BD7-5A19-432D-B202-8AA9C474D0D9Q35158376-E565EA85-FAA0-4AF9-BEF8-950C8F8BE23DQ35694088-F0688937-1D5D-4499-838C-60AC81617162Q36687751-037A55F0-DE1A-45FE-A1DA-30559BFEFE87Q37022025-1B3ADE2A-E365-4955-892A-68546CE3BAEAQ37024857-68A6A2AA-BF08-4160-923F-D151484C646FQ37089820-187D11D4-8FF5-4875-AA90-D0D91575C83FQ37166542-3409D7D0-0668-4C64-83E4-52AFC1D2DF3FQ37470099-7ABD9924-4A03-4BA7-B573-239D4D308180Q37606025-F575538C-A1EC-4FF8-8B42-35C14792CDD3Q46046188-197F8AFF-3818-44FF-BB10-433DBBB82881Q47110701-578092FA-CF63-4435-BA33-6060514E6292Q48127496-71741565-EB44-4889-BB8D-D0A5426C9E7EQ50435098-BD76F880-63BE-48F5-942D-6611B4C397F5Q53081269-DFB0AFD3-4F93-4652-B53B-F74B4A4EC9F5Q55283322-494BA7C5-B144-4B19-B6F8-AD6964070706Q58720843-C3644BC8-EDFC-4D76-AFA3-55D28F15B66BQ59127908-9E5162B4-67EB-4CB9-9A7C-78D68E9745C3
P2860
Mifepristone alters amyloid precursor protein processing to preclude amyloid beta and also reduces tau pathology.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Mifepristone alters amyloid pr ...... nd also reduces tau pathology.
@en
type
label
Mifepristone alters amyloid pr ...... nd also reduces tau pathology.
@en
prefLabel
Mifepristone alters amyloid pr ...... nd also reduces tau pathology.
@en
P2860
P50
P1476
Mifepristone alters amyloid pr ...... and also reduces tau pathology
@en
P2093
Frank M LaFerla
Kim N Green
P2860
P304
P356
10.1016/J.BIOPSYCH.2012.12.003
P407
P577
2013-01-08T00:00:00Z