Competition between splicing and polyadenylation reactions determines which adenovirus region E3 mRNAs are synthesized
about
Formation of mRNA 3' ends in eukaryotes: mechanism, regulation, and interrelationships with other steps in mRNA synthesisTwo distant upstream regions containing cis-acting signals regulating splicing facilitate 3'-end processing of avian sarcoma virus RNA.Inhibition of TRAIL-induced apoptosis and forced internalization of TRAIL receptor 1 by adenovirus proteins.Polyadenylation site selection cannot occur in vivo after excision of the 3'-terminal intron.The adenovirus E3 10.4K and 14.5K proteins, which function to prevent cytolysis by tumor necrosis factor and to down-regulate the epidermal growth factor receptor, are localized in the plasma membraneStructurally related class I and class II receptor protein tyrosine kinases are down-regulated by the same E3 protein coded for by human group C adenovirusesThe adenovirus E3/10.4K-14.5K proteins down-modulate the apoptosis receptor Fas/Apo-1 by inducing its internalization.Distinct domains in the adenovirus E3 RIDalpha protein are required for degradation of Fas and the epidermal growth factor receptor.Evidence for intracellular down-regulation of the epidermal growth factor (EGF) receptor during adenovirus infection by an EGF-independent mechanism.Point mutations upstream of the yeast ADH2 poly(A) site significantly reduce the efficiency of 3'-end formation.The adenovirus E3 14.5-kilodalton protein, which is required for down-regulation of the epidermal growth factor receptor and prevention of tumor necrosis factor cytolysis, is an integral membrane protein oriented with its C terminus in the cytoplasmThe 10,400- and 14,500-dalton proteins encoded by region E3 of adenovirus form a complex and function together to down-regulate the epidermal growth factor receptor.The 11,600-MW protein encoded by region E3 of adenovirus is expressed early but is greatly amplified at late stages of infectionMap of cis-acting sequences that determine alternative pre-mRNA processing in the E3 complex transcription unit of adenovirus.Retrovirus-mediated transfer of an adenovirus gene encoding an integral membrane protein is sufficient to down regulate the receptor for epidermal growth factor.The 10,400- and 14,500-dalton proteins encoded by region E3 of adenovirus function together to protect many but not all mouse cell lines against lysis by tumor necrosis factorA 10,400-molecular-weight membrane protein is coded by region E3 of adenovirusSplice site skipping in polyomavirus late pre-mRNA processing.Convergence of RNA cis elements and cellular polyadenylation factors in the regulation of human cytomegalovirus UL37 exon 1 unspliced RNA production.Adenovirus RIDα uncovers a novel pathway requiring ORP1L for lipid droplet formation independent of NPC1.Termination and pausing of RNA polymerase II downstream of yeast polyadenylation sitesUtilization of an intron located polyadenlyation site resulted in four novel glutamate decarboxylase transcripts.Polyadenylation precedes splicing in vitro.
P2860
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P2860
Competition between splicing and polyadenylation reactions determines which adenovirus region E3 mRNAs are synthesized
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Competition between splicing a ...... egion E3 mRNAs are synthesized
@ast
Competition between splicing a ...... egion E3 mRNAs are synthesized
@en
type
label
Competition between splicing a ...... egion E3 mRNAs are synthesized
@ast
Competition between splicing a ...... egion E3 mRNAs are synthesized
@en
prefLabel
Competition between splicing a ...... egion E3 mRNAs are synthesized
@ast
Competition between splicing a ...... egion E3 mRNAs are synthesized
@en
P2860
P356
P1476
Competition between splicing a ...... egion E3 mRNAs are synthesized
@en
P2093
P2860
P304
P356
10.1128/MCB.8.8.3291
P407
P577
1988-08-01T00:00:00Z