Termination of signaling by protease-activated receptor-1 is linked to lysosomal sorting.
about
Morphine induces endocytosis of neuronal mu-opioid receptors through the sustained transfer of Galpha subunits to RGSZ2 proteinsc-Cbl mediates ubiquitination, degradation, and down-regulation of human protease-activated receptor 2A novel protease-activated receptor-1 interactor, Bicaudal D1, regulates G protein signaling and internalizationALIX binds a YPX(3)L motif of the GPCR PAR1 and mediates ubiquitin-independent ESCRT-III/MVB sortingDown-regulation of protease-activated receptor-1 is regulated by sorting nexin 1An essential role for SNX1 in lysosomal sorting of protease-activated receptor-1: evidence for retromer-, Hrs-, and Tsg101-independent functions of sorting nexinsClathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization.Ligand-induced trafficking of the sphingosine-1-phosphate receptor EDG-1High-resolution crystal structure of human protease-activated receptor 1Regulation of GPCR activity, trafficking and localization by GPCR-interacting proteins.Enhanced effector function of CD8(+) T cells from healthy controls and HIV-infected patients occurs through thrombin activation of protease-activated receptor 1.How the protease thrombin talks to cells.Endosomal signaling by protease-activated receptors.Signal transduction by protease-activated receptorsN-linked glycosylation of protease-activated receptor-1 second extracellular loop: a critical determinant for ligand-induced receptor activation and internalizationRab5a and rab11a mediate agonist-induced trafficking of protease-activated receptor 2.Protease activated receptors: theme and variations.Modulation of protease activated receptor 1 influences human metapneumovirus disease severity in a mouse modelSustained receptor stimulation leads to sequestration of recycling endosomes in a classical protein kinase C- and phospholipase D-dependent mannerA constitutively active mutant of the human lutropin receptor (hLHR-L457R) escapes lysosomal targeting and degradation.Proteases display biased agonism at protease-activated receptors: location matters!Protease-activated receptors in the cardiovascular system.Adaptor protein complex-2 (AP-2) and epsin-1 mediate protease-activated receptor-1 internalization via phosphorylation- and ubiquitination-dependent sorting signals.Recycling and Endosomal Sorting of Protease-activated Receptor-1 Is Distinctly Regulated by Rab11A and Rab11B Proteins.Ubiquitination differentially regulates clathrin-dependent internalization of protease-activated receptor-1Ubiquitination of G protein-coupled receptors: functional implications and drug discovery.Persistent signaling by dysregulated thrombin receptor trafficking promotes breast carcinoma cell invasionUbiquitin-dependent regulation of G protein-coupled receptor trafficking and signalingPalmitoylation of protease-activated receptor-1 regulates adaptor protein complex-2 and -3 interaction with tyrosine-based motifs and endocytic sorting.Caveolae are required for protease-selective signaling by protease-activated receptor-1.Endosomes: a legitimate platform for the signaling train.Regulation of protease-activated receptor 1 signaling by the adaptor protein complex 2 and R4 subfamily of regulator of G protein signaling proteins.Proteinases, Their Extracellular Targets, and Inflammatory Signaling.Control of Adhesion GPCR Function Through Proteolytic Processing.Differential endosomal sorting of a novel P2Y12 purinoreceptor mutant.Discovery of Octahydroindenes as PAR1 Antagonists.Hepatocyte growth factor-regulated tyrosine kinase substrate (HRS) mediates post-endocytic trafficking of protease-activated receptor 2 and calcitonin receptor-like receptor.Differential sorting of human delta-opioid receptors after internalization by peptide and alkaloid agonists.A transplantable sorting signal that is sufficient to mediate rapid recycling of G protein-coupled receptors.Protease-activated receptor-1 down-regulation: a mutant HeLa cell line suggests novel requirements for PAR1 phosphorylation and recruitment to clathrin-coated pits.
P2860
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P2860
Termination of signaling by protease-activated receptor-1 is linked to lysosomal sorting.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Termination of signaling by protease-activated receptor-1 is linked to lysosomal sorting.
@en
type
label
Termination of signaling by protease-activated receptor-1 is linked to lysosomal sorting.
@en
prefLabel
Termination of signaling by protease-activated receptor-1 is linked to lysosomal sorting.
@en
P2093
P2860
P356
P1476
Termination of signaling by protease-activated receptor-1 is linked to lysosomal sorting.
@en
P2093
P2860
P304
13698-13702
P356
10.1073/PNAS.95.23.13698
P407
P577
1998-11-01T00:00:00Z