Aminoglycoside antibiotics: old drugs and new therapeutic approaches.
about
Small molecules targeting viral RNATherapeutic suppression of premature termination codons: mechanisms and clinical considerations (review)Antibiotics that target protein synthesisSelective condensation of DNA by aminoglycoside antibioticsA model for the study of ligand binding to the ribosomal RNA helix h44A structural basis for the antibiotic resistance conferred by an A1408G mutation in 16S rRNA and for the antiprotozoal activity of aminoglycosidesCrystal structures of a bioactive 6'-hydroxy variant of sisomicin bound to the bacterial and protozoal ribosomal decoding sitesActivity and interactions of liposomal antibiotics in presence of polyanions and sputum of patients with cystic fibrosisSynergistic Effect of Oleanolic Acid on Aminoglycoside Antibiotics against Acinetobacter baumanniiEx vivo treatment with a novel synthetic aminoglycoside NB54 in primary fibroblasts from Rett syndrome patients suppresses MECP2 nonsense mutationsDocking to RNA via root-mean-square-deviation-driven energy minimization with flexible ligands and flexible targets.The effect of gentamicin-induced readthrough on a novel premature termination codon of CD18 leukocyte adhesion deficiency patients.Aminoglycoside resistance rates, phenotypes, and mechanisms of Gram-negative bacteria from infected patients in upper Egypt.Binding of aminoglycoside antibiotics to helix 69 of 23S rRNACystic fibrosis transmembrane conductance regulator protein repair as a therapeutic strategy in cystic fibrosisProbing translation with small-molecule inhibitorsSynthesis and spectrum of the neoglycoside ACHN-490Toward a rationale for the PTC124 (Ataluren) promoted readthrough of premature stop codons: a computational approach and GFP-reporter cell-based assayMapping targetable sites on human telomerase RNA pseudoknot/template domain using 2'-OMe RNA-interacting polynucleotide (RIPtide) microarrays.Class 1 CF MutationsAminoglycoside modifying enzymes.Novel insights of structure-based modeling for RNA-targeted drug discovery.Aminoglycoside-induced mutation suppression (stop codon readthrough) as a therapeutic strategy for Duchenne muscular dystrophyNovel insights regarding the sigmoidal pattern of resistance to neomycin conferred by the aphII gene, in Streptomyces lividans.Mice homozygous for c.451C>T mutation in Cln1 gene recapitulate INCL phenotype.An MRPS12 mutation modifies aminoglycoside sensitivity caused by 12S rRNA mutations.Singly modified amikacin and tobramycin derivatives show increased rRNA A-site binding and higher potency against resistant bacteria.Evaluation of Synergistic Interactions Between Cell-Free Supernatant of Lactobacillus Strains and Amikacin and Genetamicin Against Pseudomonas aeruginosa.Sarcoglycanopathies: molecular pathogenesis and therapeutic prospectsBiophysical separation of Staphylococcus epidermidis strains based on antibiotic resistance.Structure-activity relationships among the kanamycin aminoglycosides: role of ring I hydroxyl and amino groupsAqueous Glycosylation of Unprotected Sucrose Employing Glycosyl Fluorides in the Presence of Calcium Ion and Trimethylamine.Rise and dissemination of aminoglycoside resistance: the aac(6')-Ib paradigm.High error rates in selenocysteine insertion in mammalian cells treated with the antibiotic doxycycline, chloramphenicol, or geneticin.Design and Synthesis of Molecular Scaffolds with Anti-infective Activity.Resistance mechanisms in Campylobacter jejuniInfluence of dimethylsulfoxide on RNA structure and ligand binding.Pharmacological rationale for antibiotic treatment of intra-abdominal infections.CFTR: A New Horizon in the Pathomechanism and Treatment of Pancreatitis.Polymyxins and analogues bind to ribosomal RNA and interfere with eukaryotic translation in vitro.
P2860
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P2860
Aminoglycoside antibiotics: old drugs and new therapeutic approaches.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Aminoglycoside antibiotics: old drugs and new therapeutic approaches.
@en
type
label
Aminoglycoside antibiotics: old drugs and new therapeutic approaches.
@en
prefLabel
Aminoglycoside antibiotics: old drugs and new therapeutic approaches.
@en
P1476
Aminoglycoside antibiotics: old drugs and new therapeutic approaches.
@en
P2093
P2888
P304
P356
10.1007/S00018-007-7034-X
P577
2007-07-01T00:00:00Z