Overexpression of the gag-pol precursor from human immunodeficiency virus type 1 proviral genomes results in efficient proteolytic processing in the absence of virion production
about
The three transfer RNAs occupying the A, P and E sites on the ribosome are involved in viral programmed -1 ribosomal frameshiftA novel self-replicating chimeric lentivirus-like particleHIV-1 frameshift efficiency is primarily determined by the stability of base pairs positioned at the mRNA entrance channel of the ribosomeIdentification of a cellular factor that modulates HIV-1 programmed ribosomal frameshiftingProcessing sites in the human immunodeficiency virus type 1 (HIV-1) Gag-Pro-Pol precursor are cleaved by the viral protease at different rates.Mechanisms and implications of programmed translational frameshiftingRibosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious useSingle amino acid changes in the human immunodeficiency virus type 1 matrix protein block virus particle productionSolution structure of the HIV-1 frameshift inducing stem-loop RNAProgrammed Ribosomal Frameshifting in SIV Is Induced by a Highly Structured RNA Stem–LoopGuanidinoneomycin B Recognition of an HIV-1 RNA HelixStructure of the HIV-1 Frameshift Site RNA Bound to a Small Molecule Inhibitor of Viral ReplicationSpecific effects of ribosome-tethered molecular chaperones on programmed -1 ribosomal frameshifting.Importance of ribosomal frameshifting for human immunodeficiency virus type 1 particle assembly and replication.Potent nonnucleoside reverse transcriptase inhibitors target HIV-1 Gag-PolPolymorphism in Gag gene cleavage sites of HIV-1 non-B subtype and virological outcome of a first-line lopinavir/ritonavir single drug regimenHIV-1 and Human PEG10 Frameshift Elements Are Functionally Distinct and Distinguished by Novel Small Molecule ModulatorsExpression and immunogenicity of sequence-modified human immunodeficiency virus type 1 subtype B pol and gagpol DNA vaccinesRequirements for incorporation of Pr160gag-pol from human immunodeficiency virus type 1 into virus-like particles.Characterization of deletion mutations in the capsid region of human immunodeficiency virus type 1 that affect particle formation and Gag-Pol precursor incorporation.Selection of peptides interfering with a ribosomal frameshift in the human immunodeficiency virus type 1Selection and characterization of small molecules that bind the HIV-1 frameshift site RNA.A single amino acid substitution in HIV-1 reverse transcriptase significantly reduces virion release.Class II transactivator (CIITA) enhances cytoplasmic processing of HIV-1 Pr55Gag.Identification of a key target sequence to block human immunodeficiency virus type 1 replication within the gag-pol transframe domain.Achieving a golden mean: mechanisms by which coronaviruses ensure synthesis of the correct stoichiometric ratios of viral proteins.Maintenance of the Gag/Gag-Pol ratio is important for human immunodeficiency virus type 1 RNA dimerization and viral infectivity.Novel gene expression mechanism in a fission yeast retroelement: Tf1 proteins are derived from a single primary translation productHIV Pol inhibits HIV budding and mediates the severe budding defect of Gag-Pol.Placement of leucine zipper motifs at the carboxyl terminus of HIV-1 protease significantly reduces virion production.Selective killing of human immunodeficiency virus infected cells by non-nucleoside reverse transcriptase inhibitor-induced activation of HIV protease.Coding sequences upstream of the human immunodeficiency virus type 1 reverse transcriptase domain in Gag-Pol are not essential for incorporation of the Pr160(gag-pol) into virus particles.Analysis of natural variants of the human immunodeficiency virus type 1 gag-pol frameshift stem-loop structureCharacterization of the frameshift stimulatory signal controlling a programmed -1 ribosomal frameshift in the human immunodeficiency virus type 1.The level of reverse transcriptase (RT) in human immunodeficiency virus type 1 particles affects susceptibility to nonnucleoside RT inhibitors but not to lamivudineA large extension to HIV-1 Gag, like Pol, has negative impacts on virion assemblyReplacement of murine leukemia virus readthrough mechanism by human immunodeficiency virus frameshift allows synthesis of viral proteins and virus replication.Elimination of protease activity restores efficient virion production to a human immunodeficiency virus type 1 nucleocapsid deletion mutant.The conformation of the mature dimeric human immunodeficiency virus type 1 RNA genome requires packaging of pol protein.Identification of putative programmed -1 ribosomal frameshift signals in large DNA databases
P2860
Q24565015-664018D1-ED34-4877-B268-2A91CE928F0CQ24611993-1BD5F13D-F67F-4241-A2F4-17F13A92315AQ24628718-FE31B628-27F1-4CB1-A6D1-054A4B3E8818Q24632938-4E9133C6-D969-4D0D-943B-52481E30F835Q24812175-9C27C6C2-4767-492F-8696-0D0D090D837DQ26852197-35675489-437D-48D6-B1E1-BB66EFB35FF3Q26970809-B6566EFC-F7EA-42AB-80E9-042F5C01D636Q27485930-5F341586-6633-44CC-9E9B-68621823EBD5Q27641759-87626B9D-9510-456B-B417-BCA474D7001BQ27648154-6D9EEF64-4513-4BF5-822B-FD77F21E851DQ27649212-0E89A48F-76A7-40FB-A273-FBBBFBCA12A5Q27666265-F313D57A-F9B2-4BA1-8F0C-7CD97F110E93Q27940051-8054DD7E-ABD9-4226-A626-3BE2831D377AQ28379495-83B40C0B-CDE9-491F-B51A-F427A4AF1286Q28469069-7059A964-708A-406E-8C15-71BD76D3CBFBQ28477151-1C4B70BF-7AA7-412B-9526-27BA1177F944Q28550143-EF4930F0-9297-4368-9FAB-1C144A5822D7Q30332833-0365785C-5A2F-49B1-AE2C-549A98298816Q30452154-89CC27C2-6ED0-46C8-BAA7-3869F3764A05Q30452616-CA3D450C-2FE1-4CBF-B3F7-CD8CB7906C51Q33325834-87F880EB-C42C-46FE-BC37-C79F4E58D4AAQ33492916-52407E71-B02D-448B-B99F-4E5AD189159AQ33558367-926333FF-1665-4E5C-985A-1886DBE2182EQ33619173-E315954E-C485-4FED-869F-123183A02F69Q33804495-7142F138-A660-4AA3-B0DA-CA9724966FF9Q33826694-508C32F4-3DA2-425E-A787-821C9FE2F38BQ33837707-FE09E912-D030-4995-9271-156E68ED3B05Q34071086-CB22DBE3-0854-447F-9C6A-478338CD8845Q34123688-33F8A0C2-8877-4D49-9848-584F94BCF51BQ34187294-1C55FD04-5D0A-436F-BF7E-851647095689Q34282609-DCEA6E57-223B-4786-805C-8F20AEF8288BQ34334594-A5817304-3822-4DB1-BE31-AE3C57191A88Q34343740-35516260-3FAD-4D85-BEDD-D13C7F687A58Q34396936-3F146735-DAB6-4C9C-960A-7661140EBD01Q34434653-B3CE56BE-8E29-4E2E-B036-604BC0749597Q34460625-7EE391DE-EE09-424C-AC29-90F024EF7469Q34757472-8DEEB4F7-55CA-48A3-947A-8A723CE04469Q34976852-947B460A-C045-4C09-8B26-7E8C3AF4702CQ34999802-AC407120-1031-4475-85BE-48BB5B6354A2Q35023495-885353FD-CD70-4051-84FA-E4203AA0C6DF
P2860
Overexpression of the gag-pol precursor from human immunodeficiency virus type 1 proviral genomes results in efficient proteolytic processing in the absence of virion production
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Overexpression of the gag-pol ...... e absence of virion production
@en
type
label
Overexpression of the gag-pol ...... e absence of virion production
@en
prefLabel
Overexpression of the gag-pol ...... e absence of virion production
@en
P2860
P1433
P1476
Overexpression of the gag-pol ...... e absence of virion production
@en
P2093
P2860
P304
P407
P577
1991-09-01T00:00:00Z