Regulation and biological activities of the autotaxin-LPA axis.
about
Structural basis of substrate discrimination and integrin binding by autotaxinIdentification and characterization of a novel lysophosphatidic acid receptor, p2y5/LPA6Recent advances in targeting the autotaxin-lysophosphatidate-lipid phosphate phosphatase axis in vivoTargeting p110gamma in gastrointestinal cancers: attack on multiple frontsRole of the autotaxin-lysophosphatidate axis in cancer resistance to chemotherapy and radiotherapyLPA is a chemorepellent for B16 melanoma cells: action through the cAMP-elevating LPA5 receptorLipid phosphate phosphatases and their roles in mammalian physiology and pathologySteroid binding to Autotaxin links bile salts and lysophosphatidic acid signallingPhospholipases of mineralization competent cells and matrix vesicles: roles in physiological and pathological mineralizationsAutotaxin: structure-function and signalingNew members of the mammalian glycerophosphodiester phosphodiesterase family: GDE4 and GDE7 produce lysophosphatidic acid by lysophospholipase D activityA metabolically-stabilized phosphonate analog of lysophosphatidic acid attenuates collagen-induced arthritisExpression and regulation of Enpp2 in rat uterus during the estrous cycleThe Autotaxin-Lysophosphatidic Acid Axis Modulates Histone Acetylation and Gene Expression during Oligodendrocyte DifferentiationAnticancer activity of FTY720: phosphorylated FTY720 inhibits autotaxin, a metastasis-enhancing and angiogenic lysophospholipase D.Lipid phosphate phosphohydrolase type 1 (LPP1) degrades extracellular lysophosphatidic acid in vivoNovel point mutations attenuate autotaxin activityRole of LPA4/p2y9/GPR23 in negative regulation of cell motilityGene by sex interaction for measures of obesity in the framingham heart study.Integrin-mediated cell surface recruitment of autotaxin promotes persistent directional cell migration.Rapid Remodeling of Invadosomes by Gi-coupled Receptors: DISSECTING THE ROLE OF Rho GTPases.Role of cAMP in the promotion of colorectal cancer cell growth by prostaglandin E2.Multiple actions of lysophosphatidic acid on fibroblasts revealed by transcriptional profilingBoronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation.Lysophosphatidylcholine activates adipocyte glucose uptake and lowers blood glucose levels in murine models of diabetes.Mammalian cell expression, purification, crystallization and microcrystal data collection of autotaxin/ENPP2, a secreted mammalian glycoprotein.Targeting the hydrophobic pocket of autotaxin with virtual screening of inhibitors identifies a common aromatic sulfonamide structural motif.LPA induces IL-6 secretion from aortic smooth muscle cells via an LPA1-regulated, PKC-dependent, and p38alpha-mediated pathwayAutotaxin signaling via lysophosphatidic acid receptors contributes to vascular endothelial growth factor-induced endothelial cell migration.Inhibition of tumor growth and angiogenesis by a lysophosphatidic acid antagonist in an engineered three-dimensional lung cancer xenograft model.Lysophosphatidic acid induces MDA-MB-231 breast cancer cells migration through activation of PI3K/PAK1/ERK signaling.Phospholipase Cgamma activation drives increased production of autotaxin in endothelial cells and lysophosphatidic acid-dependent regression.A novel self-lipid antigen targets human T cells against CD1c(+) leukemiasAutotaxin expression and its connection with the TNF-alpha-NF-kappaB axis in human hepatocellular carcinoma.Requirement of Osteopontin in the migration and protection against Taxol-induced apoptosis via the ATX-LPA axis in SGC7901 cells.Role of TAZ in Lysophosphatidic Acid-Induced Migration and Proliferation of Human Adipose-Derived Mesenchymal Stem Cells.Oxidized LDL: diversity, patterns of recognition, and pathophysiology.An integrated phosphoproteomics work flow reveals extensive network regulation in early lysophosphatidic acid signaling.Group VIA Ca2+-independent phospholipase A2 (iPLA2beta) and its role in beta-cell programmed cell death.Autotaxin and LPA receptors represent potential molecular targets for the radiosensitization of murine glioma through effects on tumor vasculature.
P2860
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P2860
Regulation and biological activities of the autotaxin-LPA axis.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Regulation and biological activities of the autotaxin-LPA axis.
@ast
Regulation and biological activities of the autotaxin-LPA axis.
@en
type
label
Regulation and biological activities of the autotaxin-LPA axis.
@ast
Regulation and biological activities of the autotaxin-LPA axis.
@en
prefLabel
Regulation and biological activities of the autotaxin-LPA axis.
@ast
Regulation and biological activities of the autotaxin-LPA axis.
@en
P1476
Regulation and biological activities of the autotaxin-LPA axis
@en
P2093
Wouter H Moolenaar
P304
P356
10.1016/J.PLIPRES.2007.02.001
P577
2007-03-16T00:00:00Z