Heparan sulfate, including that in Bruch's membrane, inhibits the complement alternative pathway: implications for age-related macular degeneration.
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Alternative Pathway Dysregulation and the Conundrum of Complement Activation by IgG4 Immune Complexes in Membranous NephropathyFactor h and properdin recognize different epitopes on renal tubular epithelial heparan sulfate.The membrane attack complex in aging human choriocapillaris: relationship to macular degeneration and choroidal thinning.Advanced glycation endproduct changes to Bruch's membrane promotes lipoprotein retention by lipoprotein lipaseA chimeric Cfh transgene leads to increased retinal oxidative stress, inflammation, and accumulation of activated subretinal microglia in miceRegulation of age-related macular degeneration-like pathology by complement factor H.Age-Related Macular Degeneration: A Disease of Systemic or Local Complement Dysregulation?Preparation of Low Molecular Weight Chondroitin Sulfates, Screening of a High Anti-Complement Capacity of Low Molecular Weight Chondroitin Sulfate and Its Biological Activity Studies in Attenuating Osteoarthritis.Role of heparan sulfate in ocular diseases.Decreased membrane complement regulators in the retinal pigmented epithelium contributes to age-related macular degeneration.Matrix metalloproteinase activity creates pro-angiogenic environment in primary human retinal pigment epithelial cells exposed to complement.Glomerular basement membrane heparan sulfate in health and disease: A regulator of local complement activation.From compliment to insult: genetics of the complement system in physiology and disease in the human retina.A novel, multiplexed targeted mass spectrometry assay for quantification of complement factor H (CFH) variants and CFH-related proteins 1-5 in human plasma.Expression of human complement factor H prevents age-related macular degeneration-like retina damage and kidney abnormalities in aged Cfh knockout mice.Complement factor H in AMD: Bridging genetic associations and pathobiology.Pentraxin 3 recruits complement factor H to protect against oxidative stress-induced complement and inflammasome overactivation.Genetics and genetic testing for age-related macular degeneration.C-Reactive Protein As a Mediator of Complement Activation and Inflammatory Signaling in Age-Related Macular Degeneration.Two distinct conformations of factor H regulate discrete complement-binding functions in the fluid phase and at cell surfaces
P2860
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P2860
Heparan sulfate, including that in Bruch's membrane, inhibits the complement alternative pathway: implications for age-related macular degeneration.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Heparan sulfate, including tha ...... -related macular degeneration.
@ast
Heparan sulfate, including tha ...... -related macular degeneration.
@en
type
label
Heparan sulfate, including tha ...... -related macular degeneration.
@ast
Heparan sulfate, including tha ...... -related macular degeneration.
@en
prefLabel
Heparan sulfate, including tha ...... -related macular degeneration.
@ast
Heparan sulfate, including tha ...... -related macular degeneration.
@en
P2093
P2860
P356
P1476
Heparan sulfate, including tha ...... e-related macular degeneration
@en
P2093
Catherine Bowes Rickman
Gregory S Hageman
Haixiang Jiang
Michael A Hauser
Michael M Frank
Pallavi Kumar
Vadim Y Arshavsky
P2860
P304
P356
10.4049/JIMMUNOL.0903596
P407
P577
2010-09-27T00:00:00Z