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Recent studies provide an updated clinical perspective on blue light-filtering IOLsRelationship between Oxidative Stress, Circadian Rhythms, and AMDPolyphenol Stilbenes: Molecular Mechanisms of Defence against Oxidative Stress and Aging-Related DiseasesThe proteomics of drusenChemistry of the retinoid (visual) cycleSimultaneous decomposition of multiple hyperspectral data sets: signal recovery of unknown fluorophores in the retinal pigment epithelium.Preliminary quantitative proteomic characterization of glaucomatous rat retinal ganglion cells.Abundant lipid and protein components of drusenPhospholipid meets all-trans-retinal: the making of RPE bisretinoidsThe utilization of fluorescence to identify the components of lipofuscin by imaging mass spectrometry.Influence of ranibizumab treatment on the extracellular matrix in patients with neovascular age-related macular degeneration.Formation of lipofuscin-like material in the RPE Cell by different components of rod outer segments.Spatial localization of A2E in the retinal pigment epitheliumQuantitative proteomics: comparison of the macular Bruch membrane/choroid complex from age-related macular degeneration and normal eyesThe retinal pigment epithelium in health and diseaseQuantitative autofluorescence and cell density maps of the human retinal pigment epithelium.Iron, the retina and the lens: a focused review.Interpretations of fundus autofluorescence from studies of the bisretinoids of the retinaMass spectrometry provides accurate and sensitive quantitation of A2E.Lack of correlation between the spatial distribution of A2E and lipofuscin fluorescence in the human retinal pigment epithelium.Similar molecules spatially correlate with lipofuscin and N-retinylidene-N-retinylethanolamine in the mouse but not in the human retinal pigment epithelium.Phototoxic action spectrum on a retinal pigment epithelium model of age-related macular degeneration exposed to sunlight normalized conditionsExperimental approaches to the study of A2E, a bisretinoid lipofuscin chromophore of retinal pigment epithelium.Distinct types of lipofuscin pigment in the hippocampus and cerebellum of aged cheirogaleid primates.Fundus Autofluorescence and RPE Lipofuscin in Age-Related Macular DegenerationThe susceptibility of the retina to photochemical damage from visible light.A chimeric Cfh transgene leads to increased retinal oxidative stress, inflammation, and accumulation of activated subretinal microglia in miceThe bisretinoids of retinal pigment epitheliumProteomic Profiling in the Brain of CLN1 Disease Model Reveals Affected Functional Modules.Lipofuscin and N-retinylidene-N-retinylethanolamine (A2E) accumulate in retinal pigment epithelium in absence of light exposure: their origin is 11-cis-retinal.Retinal photodamage mediated by all-trans-retinal.Cytotoxicity of all-trans-retinal increases upon photodegradation.Lipofuscin and A2E accumulate with age in the retinal pigment epithelium of Nrl-/- miceSpatial and Spectral Characterization of Human Retinal Pigment Epithelium Fluorophore Families by Ex Vivo Hyperspectral Autofluorescence ImagingCarboxyethylpyrrole plasma biomarkers in age-related macular degeneration.Retinal pigment epithelium (RPE) exosomes contain signaling phosphoproteins affected by oxidative stress.New insights into retinoid metabolism and cycling within the retinaBMP4 mediates oxidative stress-induced retinal pigment epithelial cell senescence and is overexpressed in age-related macular degeneration.Structures and biogenetic analysis of lipofuscin bis-retinoids.Assessing susceptibility to age-related macular degeneration with proteomic and genomic biomarkers.
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Retinal pigment epithelium lipofuscin proteomics.
@ast
Retinal pigment epithelium lipofuscin proteomics.
@en
type
label
Retinal pigment epithelium lipofuscin proteomics.
@ast
Retinal pigment epithelium lipofuscin proteomics.
@en
prefLabel
Retinal pigment epithelium lipofuscin proteomics.
@ast
Retinal pigment epithelium lipofuscin proteomics.
@en
P2093
P2860
P50
P1476
Retinal pigment epithelium lipofuscin proteomics
@en
P2093
Bogdan Gugiu
Janet R Sparrow
Joe G Hollyfield
John S Crabb
John W Crabb
Kwok-Peng Ng
Mary E Rayborn
Matthew W Davies
Michael E Boulton
P2860
P304
P356
10.1074/MCP.M700525-MCP200
P577
2008-04-24T00:00:00Z